{"orpha":46484,"name":"Oligodendroglial tumor","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":"Oligodendrogliomas are cerebral tumors that are differentiated from other gliomas on the basis of their unique genetic characteristics and better response to chemotherapy. These tumors are classified according to their grade (low grade oligodendrogliomas: grade II of the WHO classification and anaplastic oligodendrogliomas: grade III of the WHO classification) and according to their pure or mixed histology (oligoastrocytomas).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-46484/","orphanet_url":"https://www.orpha.net/en/disease/detail/46484","names":{"fr":{"name":"Tumeur oligodendrogliale","definition":"Les oligodendrogliomes sont des tumeurs cérébrales individualisées parmi les autres tumeurs gliales en raison d'anomalies génétiques particulières et d'une plus grande sensibilité à la chimiothérapie. On distingue ces tumeurs selon leur grade (oligodendrogliomes de bas grade ou de grade II selon la classification de l'OMS, et oligodendrogliomes anaplasiques ou de grade III selon la classification de l'OMS) et selon leur caractère pur ou mixte (oligoastrocytome)."},"de":{"name":"Oligodendroglialer Tumor","definition":"Oligodendrogliome sind Hirntumore, die sich von anderen Gliomen durch ihre einzigartigen genetischen Merkmale und ihr besseres Ansprechen auf eine Chemotherapie unterscheiden. Diese Tumore werden nach ihrem Grad (niedriggradige Oligodendrogliome: Grad II der WHO-Klassifikation und anaplastische Oligodendrogliome: Grad III der WHO-Klassifikation) und nach ihrer reinen oder gemischten Histologie (Oligoastrozytome) klassifiziert."},"es":{"name":"Tumor oligodendroglial","definition":"Los oligodendrogliomas son tumores cerebrales que se diferencian de otros gliomas por sus características genéticas únicas y por una mejor respuesta a la quimioterapia. Estos tumores se clasifican de acuerdo con su grado (oligodendrogliomas de grado bajo: grado II en la clasificación de la OMS y oligodendrogliomas anaplásicos: grado III en la clasificación de la OMS) y de acuerdo con su histología pura o mixta (oligoastrocitomas)."},"it":{"name":"Tumore oligodendrogliale"},"nl":{"name":"Oligodendrogliale tumor","definition":"Oligodendroglioom is een cerebrale tumor die onderscheiden wordt van andere vormen van glioom op basis van unieke genetische kenmerken en betere respons op chemotherapie. Deze tumoren worden geclassificeerd naargelang hun graad (laaggradig oligodendroglioom: graad II van de WHO-classificatie en anaplastisch oligodendroglioom: graad III van de WHO-classificatie) en naargelang hun zuivere of gemengde histologie (oligoastrocytoom)."},"pt":{"name":"Tumor oligodendroglial","definition":"Os oligodendrogliomas são tumores cerebrais distintos de outros gliomas com base nas suas características genéticas e melhor resposta à quimioterapia."},"pl":{"name":"Nowotwory gleju skąpowypustkowego"},"cs":{"name":"Oligodendrogliální tumor"},"uk":{"name":"Олігодендрогліальна пухлина","definition":"Oligodendrogliomas are cerebral tumors that are differentiated from other gliomas on the basis of their unique genetic characteristics and better response to chemotherapy. These tumors are classified according to their grade (low grade oligodendrogliomas: grade II of the WHO classification and anaplastic oligodendrogliomas: grade III of the WHO classification) and according to their pure or mixed histology (oligoastrocytomas)."},"zh":{"name":"少突胶质细胞肿瘤"},"tr":{"name":"Oligodendroglial tümör"}},"xrefs":[{"source":"MONDO","code":"0018744","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"18744","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1335110","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"13156","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":182067,"name":"Glial tumor","classifications":[181,202]}],"children":[{"orpha":251627,"name":"Oligodendroglioma grade 2","type":"Disease"},{"orpha":251630,"name":"Oligodendroglioma grade 3","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":["Multigenic/multifactorial","Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.35,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.24,"area":"United States","status":"Validated","source":"Central Brain Tumor OTHERistry of the United States 2010-2014[OTHER]_29117289[PMID]"}],"phenotypes":null}