{"orpha":459345,"name":"Immunodeficiency due to a complement cascade component deficiency","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-459345/","orphanet_url":"https://www.orpha.net/en/disease/detail/459345","names":{"fr":{"name":"Déficit immunitaire par déficit d'un composant de la cascade du complément","synonyms":["Immunodéficience due à un déficit d'un composant de la cascade du complément"]},"de":{"name":"Immundefekt durch Komponenten-Mangel der Komplement-Kaskase"},"es":{"name":"Inmunodeficiencia por deficiencia de un componente de la cascada del complemento"},"it":{"name":"Immunodeficienza da deficit di un componente della cascata del complemento"},"nl":{"name":"Immuundeficiëntie door deficiëntie van een component van complementcascade"},"pt":{"name":"Imunodeficiência por deficiência de um componente da cascata do complemento"},"pl":{"name":"Niedobór odporności spowodowany deficytem kaskady układu dopełniacza"},"cs":{"name":"Imunodeficit způsobený deficitem složky komplementové kaskády"},"uk":{"name":"Імунодефіцит, зумовлений дефіцитом компонентів каскаду комплементу"},"zh":{"name":"补体级联成份缺乏引起的免疫缺陷病"},"tr":{"name":"Kompleman kaskadı bileşen eksikliğine bağlı immün yetmezlik"}},"xrefs":[{"source":"MONDO","code":"0003832","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"3832","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5681110","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":101992,"name":"Immunodeficiency due to a complement cascade protein anomaly","classifications":[156,195]}],"children":[{"orpha":280133,"name":"Complement component 3 deficiency","type":"Disease"},{"orpha":331187,"name":"Immunodeficiency due to MASP-2 deficiency","type":"Disease"},{"orpha":169147,"name":"Immunodeficiency due to a classical component pathway complement deficiency","type":"Disease"},{"orpha":169150,"name":"Immunodeficiency due to a late component of complement deficiency","type":"Disease"},{"orpha":331190,"name":"Immunodeficiency due to ficolin3 deficiency","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}