{"orpha":443291,"name":"HIV-associated cancer","type":"Particular clinical situation in a disease or syndrome","group":"Disorder","status":"active","flags":[],"synonyms":["HIV-related cancer"],"definition":"A rare neoplastic disease characterized by occurrence in association with human immunodeficiency virus (HIV) infection. Kaposi sarcoma, aggressive B-cell lymphomas, and invasive cervical cancer are considered AIDS-defining cancers, while a variety of other cancers are known to be related to HIV, including Hodgkin lymphoma, hepatocellular carcinoma, and lung, anal, oral cavity and oropharyngeal, vulvar, and penile cancer. The majority of cancers in AIDS patients are associated with co-infection with oncogenic viruses, such as Epstein-Barr virus, human herpesvirus 8, and human papillomavirus.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-443291/","orphanet_url":"https://www.orpha.net/en/disease/detail/443291","names":{"fr":{"name":"Cancer lié à l'infection VIH","synonyms":["Cancer associé à l'infection par le VIH","Cancer lié au VIH","Cancer lié au sida"],"definition":"Maladie néoplasique rare caractérisée par l'association avec l'infection par le virus de l'immunodéficience humaine (VIH). Le sarcome de Kaposi, les lymphomes agressifs à lymphocytes B et le cancer invasif du col de l'utérus sont considérés comme des cancers définissant le SIDA, tandis que différents autres cancers sont connus pour être liés à l'infection à VIH, y compris le lymphome de Hodgkin, le carcinome hépatocellulaire et les cancers du poumon, de l'anus, de la cavité buccale et de l'oropharynx, de la vulve et du pénis. La majorité des cancers chez les patients atteints du SIDA sont associés à une co-infection à virus oncogènes, tels que le virus d'Epstein-Barr, l'herpèsvirus humain 8 et le papillomavirus humain."},"de":{"name":"HIV-assoziierte Krebsformen","definition":"Eine seltene Neoplasie, die in Verbindung mit einer Infektion mit dem Humanen Immundefizienz-Virus (HIV) auftritt. Kaposi-Sarkom, aggressive B-Zell-Lymphome und invasiver Gebärmutterhalskrebs gelten als AIDS-definierende Krebsarten, während eine Reihe anderer Krebsarten bekanntermaßen mit HIV in Verbindung stehen, darunter Hodgkin-Lymphome, Leberzellkarzinome sowie Lungen-, Anal-, Mundhöhlen- und Oropharynx-, Vulva- und Peniskrebs. Die meisten Krebserkrankungen bei AIDS-Patienten stehen im Zusammenhang mit einer Koinfektion mit onkogenen Viren wie dem Epstein-Barr-Virus, dem humanen Herpesvirus 8 und dem humanen Papillomavirus."},"es":{"name":"Cáncer asociado a VIH","definition":"Es una enfermedad neoplásica poco frecuente caracterizada por su aparición en asociación con la infección por el virus de la inmunodeficiencia humana (VIH). El sarcoma de Kaposi, los linfomas agresivos de células B y el cáncer de cuello uterino invasivo se consideran cánceres que definen el SIDA, mientras que se sabe que una variedad de otros cánceres están relacionados con el VIH, incluyendo el linfoma de Hodgkin, el carcinoma hepatocelular y el de pulmón, ano, cavidad oral y orofaringe, así como el cáncer vulvar y de pene. La mayoría de las neoplasias en pacientes con SIDA están asociadas a la coinfección con virus oncogénicos, como el virus de Epstein-Barr, el herpesvirus humano 8 y el virus del papiloma humano."},"it":{"name":"Tumori associati all'HIV"},"nl":{"name":"HIV-geassocieerde kankers","definition":"Een zeldzame neoplastische aandoening, gekenmerkt door optreden in associatie met infectie door humaan immunodeficiëntievirus (HIV). Kaposi-sarcoom, agressieve B-cellymfomen, en invasieve baarmoederhalskanker worden beschouwd als AIDS-definiërende kankers, terwijl van verschillende andere kankers geweten is dat ze gerelateerd zijn aan HIV, waaronder Hodgkin-lymfoom, hepatocellulair carcinoom, en kanker van long, anus, mondholte, orofarynx, vulva, en penis. De meerderheid van kankers bij AIDS-patiënten is geassocieerd met co-infectie door oncogene virussen, zoals Epstein-Barrvirus, humaan herpesvirus 8, en humaan papillomavirus."},"pt":{"name":"Cancro VIH-associado","definition":"Doença neoplásica rara caracterizada pela ocorrência em associação com a infeção pelo vírus da imunodeficiência humana (HIV). Sarcoma de Kaposi, linfomas agressivos de células B e cancro cervical invasivo são consideradas neoplasias definidoras de SIDA, enquanto uma variedade de outros cancros são conhecidos por estarem relacionados com HIV, incluindo linfoma de Hodgkin, carcinoma hepatocelular e cancro do pulmão, anal, cavidade oral e orofaríngeo, vulvar e peniano. A maioria dos cancros em doentes com SIDA está associada à coinfeção com vírus oncogénicos, como o vírus Epstein-Barr, o herpesvírus humano 8 e o papilomavírus humano."},"pl":{"name":"Nowotwór towarzyszący HIV","synonyms":["Nowotwór związany z HIV"],"definition":"Rzadka choroba nowotworowa, która rozwija się w związku z zakażeniem ludzkim wirusem niedoboru odporności (HIV). Za nowotwory definiujące AIDS uważa się mięsaka Kaposiego, agresywne chłoniaki komórek B i inwazyjny rak szyjki, podczas gdy z zakażeniem HIV powiązanych jest wiele innych nowotworów, w tym chłoniak Hodgkina, rak wątrobowokomórkowy oraz rak płuc, odbytu, jamy ustnej i gardła, sromu i prącia. Większość nowotworów u pacjentów z AIDS jest powiązana z jednoczesnym zakażeniem wirusami onkogennymi, takimi jak wirus Epsteina-Barr, wirus opryszczki ludzkiej typu 8 i wirus brodawczaka ludzkiego."},"cs":{"name":"HIV-asociovaný nádor","synonyms":["Nádor v souvislosti s HIV"]},"uk":{"name":"ВІЛ-асоційований рак","synonyms":["Рак, повязаний з ВІЛ"],"definition":"A rare neoplastic disease characterized by occurrence in association with human immunodeficiency virus (HIV) infection. Kaposi sarcoma, aggressive B-cell lymphomas, and invasive cervical cancer are considered AIDS-defining cancers, while a variety of other cancers are known to be related to HIV, including Hodgkin lymphoma, hepatocellular carcinoma, and lung, anal, oral cavity and oropharyngeal, vulvar, and penile cancer. The majority of cancers in AIDS patients are associated with co-infection with oncogenic viruses, such as Epstein-Barr virus, human herpesvirus 8, and human papillomavirus."},"zh":{"name":"HIV相关癌症","synonyms":["HIV相关肿瘤"]},"tr":{"name":"HIV -ilişkili kanser","synonyms":["HIV-ilişkili kanser"]}},"xrefs":[{"source":"ICD-10","code":"B21.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1C62.3Y","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1858812010%2fother"},{"source":"MONDO","code":"0018628","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680059","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":443301,"name":"OBSOLETE: HIV-related lung cancer","status":"inactive"},{"type":"Referred to","orpha":443304,"name":"OBSOLETE: HIV-related oropharyngeal cancer","status":"inactive"},{"type":"Referred to","orpha":443307,"name":"OBSOLETE: HIV-related anal cancer","status":"inactive"},{"type":"Referred to","orpha":443310,"name":"OBSOLETE: HIV-related hepatocellular carcinoma","status":"inactive"},{"type":"Referred to","orpha":443313,"name":"OBSOLETE: HIV-related penile cancer","status":"inactive"},{"type":"Referred to","orpha":443316,"name":"OBSOLETE: HIV-related Hodgkin lymphoma","status":"inactive"},{"type":"Referred to","orpha":443319,"name":"OBSOLETE: HIV-related vulvovaginal cancer","status":"inactive"},{"type":"Referred to","orpha":443322,"name":"OBSOLETE: HIV-related cervical cancer","status":"inactive"},{"type":"Referred to","orpha":443325,"name":"OBSOLETE: HIV-related Non-Hodgkin lymphoma","status":"inactive"},{"type":"Referred to","orpha":443328,"name":"OBSOLETE: HIV-related Kaposi sarcoma","status":"inactive"}],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":289635,"name":"Rare virus associated tumor","classifications":[202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":[],"prevalence":[],"phenotypes":null}