{"orpha":443227,"name":"Paratyphoid fever","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare form of salmonellosis caused by Salmonella enterica serovar Paratyphi A, B and C, characterized by typical symptoms of enteric fever including high fever, headache, abdominal pain and intestinal symptoms, dry cough, chills, and rashes, followed by a long period of recovery. The infection can be complicated by intestinal hemorrhage and perforation, as well as cardiac involvement, and may even be fatal. Transmission of the pathogen is via the fecal-oral route, with humans as the sole reservoir of infection.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-443227/","orphanet_url":"https://www.orpha.net/en/disease/detail/443227","names":{"fr":{"name":"Fièvre paratyphoïde","definition":"Forme rare de salmonellose causée par <i>Salmonella enterica serovar Paratyphi A</i>, caractérisée par des symptômes typiques de la fièvre entérique, notamment une forte fièvre, des maux de tête, des douleurs abdominales et des troubles intestinaux, une toux sèche, des frissons et des éruptions cutanées, suivie d'une longue période de récupération. Les complications sont une hémorragie et une perforation intestinale, ainsi qu'une atteinte cardiaque. L'infection peut être létale. La transmission de l'agent pathogène se fait par la voie féco-orale, l'Homme étant le seul réservoir d'infection."},"de":{"name":"Paratyphus","synonyms":["Paratyphoides Fieber"],"definition":"Eine seltene Form der Salmonellose, die durch <i>Salmonella enterica serovar</i> Serotyp Paratyphi A, B und C verursacht wird und sich durch typische Symptome des enterischen Fiebers wie hohes Fieber, Kopfschmerzen, Bauchschmerzen und Darmbeschwerden, trockenen Husten, Schüttelfrost und Hautausschläge auszeichnet, gefolgt von einer langen Erholungsphase. Die Infektion kann durch Darmblutungen und -perforationen sowie durch eine Beteiligung des Herzens kompliziert werden und sogar tödlich verlaufen. Die Übertragung des Erregers erfolgt über den fäkal-oralen Weg, wobei der Mensch das einzige Reservoir für die Infektion darstellt."},"es":{"name":"Fiebre paratifoidea","synonyms":["Fiebre entérica"],"definition":"Es una forma poco frecuente de salmonelosis causada por <i>Salmonella enterica</i> serovar Paratyphi A, B y C, caracterizada por síntomas típicos de la fiebre entérica, incluyendo fiebre alta, cefalea, dolor abdominal y síntomas intestinales, tos seca, escalofríos y erupciones, seguido de un largo período de recuperación. La infección puede complicarse por hemorragia y perforación intestinal, así como por una afectación cardíaca, pudiendo incluso ser letal. La transmisión del patógeno se realiza por la vía fecal-oral, siendo los seres humanos el único reservorio de la infección."},"it":{"name":"Febbre paratifoide","definition":"Si tratta di una forma rara di salmonellosi causata dalla Salmonella enterica di sierotipo paratifo A, B e C, caratterizzata dai sintomi tipici della febbre enterica, che comprendono la febbre elevata, la cefalea, il dolore addominale e i sintomi intestinali, la tosse secca, i brividi e le eruzioni, seguiti da un lungo periodo di convalescenza. L'infezione può associarsi ad alcune complicanze, come le emorragie e la perforazione dell'intestino, e ad un interessamento cardiaco, che possono essere letali. Il patogeno si trasmette per via oro-fecale. L'uomo è l'unico serbatoio di infezione."},"nl":{"name":"Paratyfus","definition":"Een zeldzame vorm van salmonellose, veroorzaakt door <i>Salmonella enterica</i> serotype Paratyphi A, B en C, en gekenmerkt door typische symptomen van buiktyfus, waaronder hoge koorts, hoofdpijn, abdominale pijn en intestinale symptomen, droge hoest, rillingen, en huiduitslag, gevold door een lange periode van herstel. De infectie kan gecompliceerd worden door intestinale hemorragie en perforatie, alsook betrokkenheid van hart, en kan zelfs fataal zijn. Transmissie van de pathogeen gebeurt via de fecale-orale route, en mensen zijn het enige reservoir van de infectie."},"pt":{"name":"Febre paratifoide","definition":"Forma rara de salmonelose causada por Salmonella enterica sorovar Paratyphi A, B e C, caracterizada por sintomas típicos de febre entérica, incluindo febre alta, dor de cabeça, dor abdominal e sintomas intestinais, tosse seca, calafrios e erupções cutâneas, seguido por um longo período de recuperação. A infeção pode ser complicada por hemorragia e perfuração intestinal, envolvimento cardíaco, e pode vir a ser fatal. A transmissão do patógeno é por via fecal-oral, sendo que os humanos são o único reservatório de infeção."},"pl":{"name":"Dur rzekomy"},"cs":{"name":"Paratyfoidní horečka"},"uk":{"name":"Паратиф","definition":"A rare form of salmonellosis caused by Salmonella enterica serovar Paratyphi A, B and C, characterized by typical symptoms of enteric fever including high fever, headache, abdominal pain and intestinal symptoms, dry cough, chills, and rashes, followed by a long period of recovery. The infection can be complicated by intestinal hemorrhage and perforation, as well as cardiac involvement, and may even be fatal. Transmission of the pathogen is via the fecal-oral route, with humans as the sole reservoir of infection."},"zh":{"name":"副伤寒","definition":"一种由沙门氏菌副伤寒A型引起的沙门氏菌病感染的罕见形式，其特征是肠型热，典型症状包括高烧，头痛，腹痛和肠道症状，干咳，发冷和皮疹，然后出现一个长时间的恢复期。肠道出血、穿孔以及心脏受累可导致感染复杂化，甚至可能致命。病原体的传播是通过粪口途径，人类是唯一的感染源。"},"tr":{"name":"Paratifoid ateş"}},"xrefs":[{"source":"ICD-10","code":"A01.1","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"A01.2","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"A01.3","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"A01.4","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1A08","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1780040028"},{"source":"MONDO","code":"0018626","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D010284","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0030528","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10033971","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":795,"name":"Rare form of salmonellosis","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[],"phenotypes":null}