{"orpha":443070,"name":"Hemicrania continua","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare trigeminal autonomic cephalalgia characterized by indomethacin-sensitive, persistent, strictly unilateral headache lasting for more than three months, associated with ipsilateral conjunctival injection, lacrimation, nasal congestion, rhinorrhea, forehead and facial sweating, miosis, ptosis, eyelid edema, and/or restlessness or agitation, and not better accounted for by another type of headache. Migrainous symptoms such as photophobia are often observed. The headache may be continuous (unremitting subtype) or interrupted by remission periods of more than 24 hours (remitting subtype).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-443070/","orphanet_url":"https://www.orpha.net/en/disease/detail/443070","names":{"fr":{"name":"Hémicrânie continue","definition":"Céphalée trigémino-autonomique rare caractérisée par une céphalée sensible à l'indométhacine, persistante, strictement unilatérale, durant plus de trois mois, associée à une injection conjonctivale ipsilatérale, un larmoiement, une congestion nasale, une rhinorrhée, une transpiration frontale et faciale, un myosis, un ptosis, un oedème des paupières et/ou une agitation, et ne pouvant s'apparenter à un autre type de céphalée. Des symptômes de migraine tels que la photophobie sont souvent observés. La céphalée peut être continue (sous-type non rémittent) ou interrompue par des périodes de rémission de plus de 24 heures (sous-type rémittent)."},"de":{"name":"Hemicrania continua","definition":"Bei der Hemicrania continua handelt es sich um eine seltene, auf Indometacin ansprechende, trigemino-autonome Kopfschmerzform, die durch einen typischerweise seitengebundenen, kontinuierlichen, einseitigen Kopfschmerz von mäßiger Intensität mit wiederkehrenden Episoden von Exazerbationen schwerer Intensität gekennzeichnet ist, die mehr als 3 Monate andauern und bei denen keine strukturellen Hirn- oder Gefäßläsionen vorliegen. Ipsilaterale kraniale autonome Symptome (Tränenfluss, konjunktivale Injektion, nasale Kongestion oder Rhinorrhoe, Ptosis/Miosis), Unruhe und/oder migräneartige Züge werden während der Exazerbationen beobachtet. Häufig werden migräneartige Symptome wie Photophobie beobachtet. Die Kopfschmerzen können kontinuierlich auftreten (unremittierender Subtyp) oder von Remissionsphasen von mehr als 24 Stunden unterbrochen sein (remittierender Subtyp)."},"es":{"name":"Hemicránea continua","definition":"Es una cefalea trigémino-autonómica poco frecuente caracterizada por cefalea típicamente unilateral, persistente, sensible a la indometacina, de duración superior a 3 meses y asociada a inyección conjuntival ipsilateral, lagrimeo, congestión nasal, rinorrea, sudoración de la frente y la cara, miosis, ptosis, edema palpebral y/o inquietud o agitación, que no puede explicarse mejor en base a otro tipo de cefalea. A menudo se observa síntomas migrañosos como la fotofobia. La cefalea puede ser continua (subtipo constante) o interrumpida por períodos de remisión de más de 24 horas (subtipo recurrente)."},"it":{"name":"Emicrania continua","definition":"Si tratta di una cefalea autonomica trigeminale rara, caratterizzata da cefalea persistente, monolaterale, sensibile all'indometacina, di durata superiore ai tre mesi, associata all' iniezione della congiuntiva omolaterale, lacrimazione, congestione nasale, rinorrea, iperidrosi della fronte e del viso, miosi, ptosi, edema palpebrale, e/o irrequietezza o agitazione, che non possono essere ricondotti ad un altro tipo di cefalea. Spesso si osservano sintomi emicranici come la fotofobia. La cefalea può essere continua (sottotipo non remittente) o interrotta da periodi di remissione di durata superiore alle 24 ore (sottotipo remittente)."},"nl":{"name":"Hemicrania continua","definition":"Een zeldzame trigeminale autonome cefalalgie, gekenmerkt door voor indometacine gevoelige, persisterende, louter unilaterale hoofdpijn die langer dan drie maanden duurt, geassocieerd met ipsilaterale hyperemie van conjunctiva, lacrimatie, neuscongestie, rinorroe, zweten aan voorhoofd en aangezicht, miose, ptosis, oedeem van ooglid, en/of rusteloosheid of agitatie, en die niet beter kan verklaard worden door een ander type van hoofdpijn. Migraineuze symptomen zoals fotofobie worden vaak waargenomen. De hoofdpijn kan continu optreden (niet-remitterend subtype) of onderbroken worden door periodes van remissie die langer dan 24 uur duren (remitterend subtype)."},"pt":{"name":"Hemicrania continua"},"pl":{"name":"Hemikrania ciągła"},"cs":{"name":"Hemicrania continua"},"uk":{"name":"Постійна геморагія","definition":"A rare trigeminal autonomic cephalalgia characterized by indomethacin-sensitive, persistent, strictly unilateral headache lasting for more than three months, associated with ipsilateral conjunctival injection, lacrimation, nasal congestion, rhinorrhea, forehead and facial sweating, miosis, ptosis, eyelid edema, and/or restlessness or agitation, and not better accounted for by another type of headache. Migrainous symptoms such as photophobia are often observed. The headache may be continuous (unremitting subtype) or interrupted by remission periods of more than 24 hours (remitting subtype)."},"zh":{"name":"连续性半侧颅痛","definition":"连续性偏头痛是一种罕见的吲哚美辛反应性三叉神经自主性头痛，其特征是典型的侧锁性，持续性，单侧性中等强度头痛，合并反复发作强度对着次数加剧的疼痛，持续3个月以上，没有结构性脑病或血管病变。在病情加重期间观察到同侧颅脑自主神经症状（流泪，结膜刺痛，鼻充血或鼻漏，上睑下垂/瞳孔缩小，发作加重期间有躁动不安和/或偏头痛。"},"tr":{"name":"Hemikrani kontinua"}},"xrefs":[{"source":"ICD-10","code":"G44.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"8A82","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1093161847"},{"source":"MONDO","code":"0018615","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C2349425","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"10795","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10090227","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":157843,"name":"Trigeminal autonomic cephalalgia","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":[],"prevalence":[],"phenotypes":null}