{"orpha":440233,"name":"Congenital abducens nerve palsy","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Benign congenital sixth cranial nerve palsy","Congenital CNVI palsy"],"definition":"A rare neuro-ophthalmological disease characterized by dysfunction of the ipsilateral lateral rectus muscle with esotropia in primary position, limited or no abduction of the eyeball, and compensatory horizontal face turn toward the palsied eye. The condition commonly resolves spontaneously.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-440233/","orphanet_url":"https://www.orpha.net/en/disease/detail/440233","names":{"fr":{"name":"Paralysie congénitale du nerf abducens","synonyms":["Lésion CNVI congénitale","Paralysie bénigne congénitale du sixième nerf crânien"],"definition":"Maladie neuro-ophtalmologique rare caractérisée par le dysfonctionnement du muscle droit externe de l'oeil ipsilatéral accompagné d'une exotropie en position primaire, d'une abduction limitée ou d'une absence d'abduction du globe oculaire et d'un mouvement compensatoire de rotation horizontale de la tête vers l'oeil paralysé. La maladie est généralement spontanément résolutive."},"de":{"name":"Abduzensparese, kongenitale","synonyms":["Benigne kongenitale Parese des sechsten Hirnnerven","Hirnnerv VI-Lähmung, kongenitale","Kongenitale Lähmung des Nervus abducens"],"definition":"Eine seltene neuro-ophthalmologische Erkrankung, die durch eine Funktionsstörung des ipsilateralen Musculus rectus lateralis mit Esotropie in Primärposition, begrenzter oder fehlender Abduktion des Augapfels und kompensatorischer horizontaler Gesichtsdrehung zum gelähmten Auge hin gekennzeichnet ist. Die Störung bildet sich in der Regel spontan zurück."},"es":{"name":"Parálisis congénita del nervio abducens","synonyms":["Parálisis congénita CNVI","Parálisis congénita benigna del sexto par craneal","Parálisis congénita del nervio abducente"],"definition":"Es una enfermedad neuro-oftalmológica poco frecuente caracterizada por disfunción del músculo recto lateral ipsilateral con endotropía en posición primaria, abducción limitada o nula del globo ocular y giro compensatorio horizontal de la cara hacia el ojo paralizado. Por lo general, la afección remite de manera espontánea."},"it":{"name":"Paralisi congenita del nervo abducente","synonyms":["Paralisi congenita benigna del sesto nervo cranico","Paralisi congenita del CNVI"],"definition":"Si tratta di una malattia neuro-oftalmologica rara, caratterizzata da disfunzione del muscolo retto laterale omolaterale con esotropia in posizione primaria, limitata o assente abduzione del bulbo oculare, e rotazione orizzontale compensatoria della testa verso l'occhio paralizzato. In genere la malattia si risolve spontaneamente."},"nl":{"name":"Congenitale paralyse van nervus abducens","synonyms":["Congenitale CNVI-verlamming","Goedaardige congenitale paralyse van zesde hersenzenuw"],"definition":"Een zeldzame neuro-oftalmologische aandoening, gekenmerkt door disfunctie van de ipsilaterale musculus rectus lateralis (zijdelingse rechte oogspier) met esotropie in primaire positie, beperkte of geen abductie van oogbol, en compensatoire horizontale draaiing van het aangezicht in de richting van het verlamde oog. De aandoening verdwijnt doorgaans spontaan."},"pt":{"name":"Paralisia congénita do nervo abducens"},"pl":{"name":"Wrodzone porażenie nerwu odwodzącego","synonyms":["Wrodzone łagodne porażenie szóstego nerwu czaszkowego","Wrodzone porażenie CNVI"]},"cs":{"name":"Vrozená paréza nervus abducens","synonyms":["Benigní vrozená paréza šestého hlavového nervu","Vrozená paréza n.VI"]},"uk":{"name":"Вроджений абдукційний нервовий параліч","synonyms":["Доброякісний вроджений параліч шостого черепного нерва","Вроджений CNVI параліч"],"definition":"A rare neuro-ophthalmological disease characterized by dysfunction of the ipsilateral lateral rectus muscle with esotropia in primary position, limited or no abduction of the eyeball, and compensatory horizontal face turn toward the palsied eye. The condition commonly resolves spontaneously."},"zh":{"name":"先天性展神经麻痹","synonyms":["良性先天性第六颅神经麻痹"]},"tr":{"name":"Doğumsal abdusens sinir felci","synonyms":["Doğumsal CNVI felci","Selim doğumsal altıncı kraniyal sinir felci"]}},"xrefs":[{"source":"ICD-10","code":"Q07.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9C81.2","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"2004845959"},{"source":"MONDO","code":"0018600","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1302994","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":522510,"name":"Rare genetic ophthalmic disorder with cranial nerve involvement","classifications":[156]},{"orpha":519349,"name":"Rare ophthalmic disorder with cranial nerve involvement","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Neonatal"],"prevalence":[],"phenotypes":null}