{"orpha":431344,"name":"Urachal sinus","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Urachal sinus is a type of congenital urachal anomaly resulting from the failure of the umbilical end of the urachus to close, without continuity to the bladder, and that is usually asymptomatic but can present with continuous cloudy umbilical discharge, tender midline infraumbilical mass and fever when infected.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-431344/","orphanet_url":"https://www.orpha.net/en/disease/detail/431344","names":{"fr":{"name":"Sinus de l'ouraque","synonyms":["Sinus ouraquien"],"definition":"Le sinus de l'ouraque est un type d'anomalie congénitale de l'ouraque résultant de l'absence de fermeture de la partie ombilicale de l'ouraque, sans continuité dans la vessie. Il est généralement asymptomatique mais peut se présenter par un écoulement ombilical purulent continu, une masse sous-ombilicale douloureuse et une fièvre en cas d'infection."},"de":{"name":"Urachussinus"},"es":{"name":"Seno uracal","definition":"Es un tipo de anomalía uracal congénita que resulta del fallo de cierre del extremo umbilical del uraco, sin continuidad a la vejiga, y que suele ser asintomático aunque se puede presentar como un drenaje turbio continuado umbilical, una masa blanda en la línea media infraumbilical y fiebre cuando se infecta."},"it":{"name":"Seno uracale","definition":"Il seno uracale è un'anomalia congenita dell'uraco (si veda questo termine), causata dalla mancata chiusura dell'estremità ombelicale dell'uraco, che esita nell'assenza di continuità verso la vescica. Di solito i pazienti sono asintomatici, ma possono presentare continue perdite ombelicali torbide, una massa intraombelicale morbida localizzata sulla linea mediana e febbre (in caso di infezione)."},"nl":{"name":"Urachussinus","definition":"Urachale sinus is een type van congenitale urachale anomalie (zie deze term) dat het gevolg is van het niet sluiten van de urachus aan de kant van de navel, zonder doorgang naar de blaas, en dat doorgaans asymptomatisch is maar zich kan voordoen met een onafgebroken troebele afscheiding uit de navel, een zachte infra-umbilicale massa op de middellijn en koorts bij infectie."},"pt":{"name":"Seio uracal"},"pl":{"name":"Zatoka moczownika"},"cs":{"name":"Urachální sinus"},"uk":{"name":"Пазуха урахуса","definition":"Urachal sinus is a type of congenital urachal anomaly (see this term) resulting from the failure of the umbilical end of the urachus to close, without continuity to the bladder, and that is usually asymptomatic but can present with continuous cloudy umbilical discharge, tender midline infraumbilical mass and fever when infected."},"zh":{"name":"脐尿窦","definition":"尿道窦是一种先天性尿道异常（见此术语），是由于脐尿管远端无法在其与膀胱的连接点闭合引起，通常无症状，但可出现持续的云絮状排出物，脐带以下中线压痛，感染可合并发烧。"},"tr":{"name":"Urakial sinüs"}},"xrefs":[{"source":"ICD-10","code":"Q64.4","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LB03.0","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1174996735"},{"source":"MONDO","code":"0018552","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C3472657","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":435743,"name":"Congenital urachal anomaly","classifications":[147,185,188,233]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Infancy","Neonatal"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2025-10-08","source":"36895469[PMID]_34277280[PMID]","terms":[{"hpo":"HP:0002027","label":"Abdominal pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:6000171","label":"Abdominal wall mass","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0004321","label":"Bladder fistula","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002664","label":"Neoplasm","frequency":"Very rare (<4-1%)","criteria":null}]}}