{"orpha":431156,"name":"Primary immunodeficiency with predisposition to severe viral infection","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-431156/","orphanet_url":"https://www.orpha.net/en/disease/detail/431156","names":{"fr":{"name":"Déficit immunitaire primaire avec prédisposition aux infections virales sévères","synonyms":["Immunodéficience primaire avec prédisposition aux infections virales sévères"]},"de":{"name":"Immundefekt, primärer, mit Prädisposition zur schweren Virusinfektion"},"es":{"name":"Inmunodeficiencia primaria con predisposición a infección viral grave"},"it":{"name":"Immunodeficienza primitiva con predispozione alle infezioni virali gravi"},"nl":{"name":"Primaire immuundeficiëntie met vatbaarheid voor ernstige virale infectie"},"pt":{"name":"Imunodeficiência primária com predisposição a infeção viral grave"},"pl":{"name":"Pierwotny Niedobór odporności z predyspozycją do ciężkich zakażeń wirusowych"},"cs":{"name":"Primární imunodeficit s predispozicí k těžkým virovým infekcím"},"uk":{"name":"Первинний імунодефіцит зі схильністю до тяжких вірусних інфекцій"},"zh":{"name":"原发性免疫缺陷伴严重病毒易感"},"tr":{"name":"Ağır viral enfeksiyona yatkınlık ile seyreden primer immün yetmezlik"}},"xrefs":[{"source":"MONDO","code":"18545","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5681211","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98004,"name":"Rare immune disease"},"parents":[{"orpha":101988,"name":"Primary immunodeficiency due to a defect in innate immunity","classifications":[156,195]}],"children":[{"orpha":437552,"name":"Autosomal recessive primary immunodeficiency with defective spontaneous natural killer cell cytotoxicity","type":"Disease"},{"orpha":574918,"name":"Predisposition to severe viral infection due to IRF7 deficiency","type":"Disease"},{"orpha":431166,"name":"Primary immunodeficiency with post-measles-mumps-rubella vaccine viral infection","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}