{"orpha":411696,"name":"OBSOLETE: Proton-pump inhibitor-responsive esophageal eosinophilia","type":"Disease","group":"Disorder","status":"inactive","flags":["Obsolete entity"],"synonyms":[],"definition":null,"note":"This entity has been obsoleted from the Orphanet nomenclature of rare diseases.<br/><br/>Instead, consider using Primary eosinophilic gastrointestinal disease","url":"https://raremap.alftech.space/d/ORPHA-411696/","orphanet_url":"https://www.orpha.net/en/disease/detail/411696","names":{"fr":{"name":"OBSOLETE : Eosinophilie oesophagienne répondant aux inhibiteurs de la pompe à protons"},"de":{"name":"OBSOLET: Protonenpumpenhemmer-responsive eosinophile Ösophagitis"},"es":{"name":"OBSOLETO: Eosinofilia esofágica con respuesta a inhibidores de la bomba de protones"},"it":{"name":"OBSOLETO: Eosinofilia esofagea sensibile agli inibitori della pompa protonica"},"nl":{"name":"OBSOLEET: Protonpompinhibitor-responsieve oesofageale eosinofilie","synonyms":["NIET ZELDZAME ZIEKTE IN EUROPA: PPIRee","NIET ZELDZAME ZIEKTE IN EUROPA: PPI-REE","NIET ZELDZAME ZIEKTE IN EUROPA: PPI-responsieve oesofageale eosinofilie"]},"pt":{"name":"OBSOLETO: Eosinofilia esofágica sensível aos inibidores da bomba de protões"},"pl":{"name":"NIEAKTUALNE: Eozynofilia przełyku wrażliwa na inhibitor pompy protonowej","definition":"*Eozynofilia przełyku wrażliwa na inhibitory pompy protonowej jest rzadką chorobą gastroenterologiczną, która charakteryzuje się cechami klinicznymi, endoskopowymi i histologicznymi typowymi dla eozynofilowego zapalenia przełyku (tj. objawowej dysfunkcji przełyku z naciekiem błony śluzowej z dominacją eozynofili) i która całkowicie ustępuje pod wpływem terapii inhibitorem pompy proteinowej."},"cs":{"name":"NEAKTUÁLNÍ: Ezofageální eosinofilie reagující na léčbu inhibitory protonové pumpy","synonyms":["NEAKTUÁLNÍ: PPI-REE","NEAKTUÁLNÍ: PPI-responzivní esofageální eosinofilie","NEAKTUÁLNÍ: PPIRee"]},"uk":{"name":"Еозинофілія стравоходу, чутлива до інгібітору протонної помпи","synonyms":["PPIRee","PPI-REE","Еозинофілія стравоходу, що реагує на ІПП"],"definition":"Proton-pump inhibitor-responsive esophageal eosinophilia (PPI-REE) is a rare, gastroenterologic disease characterized by typical clinical, endoscopic and histological features of eosinophilic oesophagitis (i.e. symptomatic oesophageal dysfunction associated with eosinophil-predominant mucose infiltrate) which completely remits upon proton pump inhibitor therapy."},"zh":{"name":"质子泵抑制剂反应性食管嗜酸性粒细胞增多症","synonyms":["PPI-反应性食管嗜酸粒细胞增多"],"definition":"质子泵抑制剂反应性食管嗜酸粒细胞增多症（PPI-REE）是一种罕见的胃肠道疾病，其特征为特异性临床和内镜表现，以及嗜酸性食管炎的典型组织学特征（即与嗜酸性粒细胞为主的粘液浸润的症状性食管功能障碍），可通过质子泵抑制剂治愈。"},"tr":{"name":"Proton pompası inhibitörüne duyarlı özofagus eozinofili","synonyms":["PPIRee","PPI-REE","PPI-yanıtlı özofageal eozinofili"]}},"xrefs":[],"associations":[{"type":"Referred to","orpha":402029,"name":"Primary eosinophilic gastrointestinal disease"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}