{"orpha":399329,"name":"Epiphysiolysis of the hip","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Slipped upper femoral epiphysis","Epiphysiolysis of the upper femur","Femoral head epiphysiolysis","SCFE","SUFE","Slipped capital femoral epiphysis"],"definition":"Epiphysiolysis of the hip is a rare osteonecrosis disorder characterized by unilateral or bilateral disruption of the capital femoral physis with varying degrees of posterior epiphysis translation and simultaneous anterior metaphysis displacement. Patients typically present in pre-adolescence/adolescence with pain of variable intensity in varying locations (hip, groin, thigh, knee).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-399329/","orphanet_url":"https://www.orpha.net/en/disease/detail/399329","names":{"fr":{"name":"Epiphysiolyse de la hanche","synonyms":["EFS","Epiphysiolyse fémorale supérieure","Glissement épiphysaire fémoral supérieur","SCFE","SUFE"],"definition":"Ostéonécrose rare caractérisée par le décollement épiphysaire unilatéral ou bilatéral de la tête fémorale avec un glissement, de degré variable, de l'épiphyse postérieure et un déplacement de la métaphyse antérieure. Les signes cliniques sont des douleurs d'intensité variable à différents endroits (hanche, aine, cuisse, genou) apparaissant généralement pendant la préadolescence ou l'adolescence."},"de":{"name":"Epiphysiolyse der Hüfte","synonyms":["Ablösung der Femurkopf-Epiphyse","Epiphysiolyse des Femurkopfes","Epiphysiolyse des oberen Femur","SCFE","SUFE","Verschiebung der oberen Femurepiphyse"],"definition":"Die Epiphysenlösung der Hüfte ist eine seltene Osteonekrose, die durch eine einseitige oder bilaterale Störung des Kopf-Hals-Übergangs mit unterschiedlichem Grad an posteriorer Epiphysenübersetzung und gleichzeitiger anteriorer Metaphysenversetzung gekennzeichnet ist. Patienten präsentieren sich typischerweise vor der Adoleszenz/Jugend mit Schmerzen unterschiedlicher Intensität an verschiedenen Stellen (Hüfte, Leiste, Oberschenkel, Knie)."},"es":{"name":"Epifisiolisis de cadera","synonyms":["Deslizamiento de la epífisis capital femoral","Deslizamiento de la epífisis de la cabeza femoral","Epifisiolisis de la cabeza femoral","Epifisiolisis del fémur superior","SCFE","SUFE"],"definition":"La epifisiólisis de cadera, es un trastorno de osteonecrosis poco frecuente caracterizado por una disrupción bilateral o unilateral de la fisis (cartílago de crecimiento) de la cabeza femoral con diversos grados de desplazamiento posterior de la epífisis y anterior simultáneo de la metáfisis. Los afectados suelen presentar dolor de intensidad variable en diferentes localizaciones (cadera, ingle, muslo, rodilla) en la preadolescencia / adolescencia."},"it":{"name":"Epifisiolisi dell'anca","synonyms":["Epifisiolisi del femore superiore","Epifisiolisi della testa del femore"],"definition":"L' epifisiolisi dell'anca è una malattia rara da osteonecrosi, caratterizzata dalla compromissione mono- o bilaterale delle fisi della testa del femore, associata alla dislocazione posteriore di grado variabile delle epifisi e alla concomitante dislocazione anteriore delle metafisi. Di solito i pazienti presentano dolore di intensità variabile in diversi punti (anche, inguine, coscia, ginocchio) durante la preadolescenza/adolescenza."},"nl":{"name":"Epifysiolyse van heup","synonyms":["Epifysiolyse van bovenste femur","Epifysiolyse van femurkop","SCFE","SUFE","Verschuiving van bovenste femurepifyse"],"definition":"Epifysiolyse van de heup is een zeldzame osteonecrose die gekarakteriseerd wordt door uni- of bilaterale ontwrichting van de groeischijf van de heupkop met variabele gradaties van posterieure translatie van de epifyse en simultane anterieure verschuiving van de metafyse. Patiënten presenteren zich doorgaans in de pre-adolescentie/adolescentie met pijn met variabele intensiteit op wisselende locaties (heup, lies, dij, knie)."},"pt":{"name":"Epifisiólise da anca"},"pl":{"name":"Epifizjoliza stawu biodrowego","synonyms":["Epifizjoliza głowy kości udowej","Epiphysiolysis of the upper femur"],"definition":"*Epifizjoliza stawu biodrowego jest rzadkim typem martwicy kości, która charakteryzuje się jednostronnym lub obustronnym odwarstwieniem nasady głowy kości udowej, z zajęciem w różnym stopniu tylnej nasady kości udowej i jednoczesnym przemieszczeniem przedniej przynasady. Objawy kliniczne typowo pojawiają się przed okresem dojrzewania/w okresie dojrzewania i charakteryzują się bólem o zmiennym nasileniu w różnych lokalizacjach (biodro, pachwina, udo, kolano)."},"cs":{"name":"Epifyzeolýza kyčle","synonyms":["Epifyzeolýza proximálního femuru","Epifyzeolýza hlavice femuru"]},"uk":{"name":"Епіфізіоліз стегна","synonyms":["Епіфізіоліз верхньої частини стегнової кістки","Епіфізіоліз головки стегнової кістки","SCFE","Зсув капілярного епіфіза стегнової кістки","Зсув верхнього епіфіза стегнової кістки","SUFE"],"definition":"Epiphysiolysis of the hip is a rare osteonecrosis disorder characterized by unilateral or bilateral disruption of the capital femoral physis with varying degrees of posterior epiphysis translation and simultaneous anterior metaphysis displacement. Patients typically present in pre-adolescence/adolescence with pain of variable intensity in varying locations (hip, groin, thigh, knee)."},"zh":{"name":"髋关节骨骺分离","synonyms":["股骨头骨骺滑脱"],"definition":"髋关节骨骺分离是一种罕见的骨坏死疾病，其特征是单侧或双侧股骨头骨骺断裂，并伴有不同程度的后骨骺平移和同时发生的前干骺端移位。患者症状通常出现在青春期前/青春期，q且不同部位(臀部、腹股沟、大腿、膝盖)的疼痛强度可不同。"},"tr":{"name":"Kalçanın epifizyolizi","synonyms":["SCFE","SUFE","Femur başı epifizyolizi","Üst femoral epifiz kayması","Üst femurun epifizyolizi","Femur başı epifiz kayması"]}},"xrefs":[{"source":"ICD-10","code":"M93.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"FB82.2","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"168053259"},{"source":"MONDO","code":"0018382","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D060048","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0149887","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93419,"name":"Rare bone disease"},"parents":[{"orpha":399158,"name":"Osteonecrosis","classifications":[196,199]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Childhood"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}