{"orpha":398961,"name":"Mucinous adenocarcinoma of ovary","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Ovarian mucinous adenocarcinoma"],"definition":"Mucinous adenocarcinoma of ovary is a rare, malignant epithelial tumor of the ovary characterized, macroscopically, by a large, usually unilateral tumor with smooth surface and evenly distributed cystic and solid areas and, histologically, by a complex papillary growth pattern with microscopic cystic glands and necrotic debris. Patients often present with pelvic pain and pressure, abdominal mass or gastrointestinal problems such as early satiety or bloating.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-398961/","orphanet_url":"https://www.orpha.net/en/disease/detail/398961","names":{"fr":{"name":"Adénocarcinome mucineux de l'ovaire","definition":"L'adénocarcinome mucineux de l'ovaire est une tumeur épithéliale de l'ovaire, maligne et rare. Sur le plan macroscopique, elle se caractérise par une grande tumeur généralement unilatérale, présentant une surface lisse et des zones kystiques et solides réparties de manière uniforme. Sur le plan histologique, elle se caractérise par un schéma de croissance papillaire complexe, et au niveau microscopique, par des glandes kystiques et des débris nécrotiques. Les patients présentent souvent une douleur et une pression pelviennes, une masse abdominale ou des troubles gastro-intestinaux, tels qu'une satiété précoce ou des ballonnements."},"de":{"name":"Muzinöses Adenokarzinom des Ovars","synonyms":["Adenokarzinom, muzinöses ovarielles"],"definition":"Das muzinöse Adenokarzinom des Ovars ist ein seltener, bösartiger Epitheltumor des Ovars, der makroskopisch durch einen großen, meist einseitigen Tumor mit glatter Oberfläche und gleichmäßig verteilten zystischen und soliden Bereichen und histologisch durch ein komplexes papilläres Wachstumsmuster mit mikroskopischen zystischen Drüsen und nekrotischen Zelltrümmern gekennzeichnet ist. Die Patienten stellen sich häufig mit Beckenschmerzen und Druckgefühl, abdominaler Masse oder gastrointestinalen Problemen wie frühzeitiger Sättigung oder Blähungen vor."},"es":{"name":"Adenocarcinoma mucinoso de ovario","synonyms":["Adenocarcinoma ovárico mucinoso"],"definition":"El adenocarcinoma mucinoso de ovario es un tumor epitelial maligno del ovario poco frecuente caracterizado, macroscópicamente, por un tumor grande, generalmente unilateral, con superficie lisa y áreas quísticas y sólidas uniformemente distribuidas e, histológicamente, por un complejo patrón de crecimiento papilar con glándulas quísticas microscópicas y restos necróticos. A menudo, las mujeres afectadas presentan dolor y presión pélvica, masa abdominal o problemas gastrointestinales tales como saciedad temprana o hinchazón."},"it":{"name":"Adenocarcinoma mucinoso dell'ovaio","synonyms":["Adenocarcinoma mucinoso ovarico"],"definition":"L'adenocarcinoma mucinoso dell'ovaio è un tumore epiteliale maligno raro dell'ovaio; dal punto di vista macroscopico è caratterizzato da una massa di ampie dimensioni, di solito monolaterale, con superficie liscia e aree cistiche e solide distribuite in maniera uniforme; dal punto di vista istologico presenta una crescita papillare complessa, con ghiandole cistiche microscopiche e detriti necrotici. Spesso le pazienti presentano dolore e pressione a livello pelvico, una massa addominale o problemi gastrointestinali come la sazietà precoce o il gonfiore addominale."},"nl":{"name":"Mucineus adenocarcinoom van ovarium","synonyms":["Mucineus adenocarcinoom van eierstok","Ovarieel mucineus adenocarcinoom"],"definition":"Mucineus adenocarcinoom van het ovarium is een zeldzame, maligne epitheliale tumor van het ovarium die macroscopisch gekarakteriseerd wordt door een grote, meestal unilaterale tumor met een glad oppervlak en gelijk verdeelde cystische en solide gebieden, en histologisch door een complex papillair groeipatroon met microscopisch cystische klieren en necrotische restanten. Patiënten vertonen vaak pijn en druk in het bekken, een buikgezwel of gastro-intestinale problemen zoals een snel verzadigingsgevoel en een opgeblazen gevoel."},"pt":{"name":"Adenocarcinoma mucinoso do ovário","synonyms":["Adenocarcinoma mucinoso ovárico"]},"pl":{"name":"Gruczolakorak śluzowy jajnika","synonyms":["Gruczolakorakoiak śluzowy jajnika"]},"cs":{"name":"Mucinózní adenokarcinom ovaria","synonyms":["Ovariální mucinózní adenokarcinom"]},"uk":{"name":"Муцинозна аденокарцинома яєчника","synonyms":["Муцинозна аденокарцинома яєчників"],"definition":"Mucinous adenocarcinoma of ovary is a rare, malignant epithelial tumor of the ovary characterized, macroscopically, by a large, usually unilateral tumor with smooth surface and evenly distributed cystic and solid areas and, histologically, by a complex papillary growth pattern with microscopic cystic glands and necrotic debris. Patients often present with pelvic pain and pressure, abdominal mass or gastrointestinal problems such as early satiety or bloating."},"zh":{"name":"卵巢粘液性腺癌","synonyms":["卵巢粘液性腺癌"],"definition":"卵巢粘液性腺癌是一种少见的卵巢恶性上皮性肿瘤，肉眼上以单侧大肿瘤为特征，肿瘤表面光滑，囊性和实质区分布均匀，组织学上表现为复杂的乳头状生长模式，伴有微小的囊腺和坏死的碎片。患者常出现盆腔疼痛和压痛、腹部肿块或早饱、腹胀等胃肠道问题。"},"tr":{"name":"Overin müsinöz adenokarsinomu","synonyms":["Overin müsinöz adenokarsinomu"]}},"xrefs":[{"source":"ICD-10","code":"C56","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2C73.04","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"869438441"},{"source":"MONDO","code":"0005601","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4518746","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":398934,"name":"Malignant epithelial tumor of ovary","classifications":[202,205]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.85,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.497,"area":"Austria","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.883,"area":"Belgium","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.815,"area":"Croatia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.995,"area":"Czech Republic","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.666,"area":"Germany","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.469,"area":"Iceland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.706,"area":"Ireland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.666,"area":"Italy","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.503,"area":"Latvia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.567,"area":"Lithuania","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.717,"area":"Norway","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.665,"area":"Poland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.49,"area":"Portugal","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.945,"area":"Slovakia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.601,"area":"Slovenia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.695,"area":"Spain","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.563,"area":"Switzerland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.76,"area":"Netherlands","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.815,"area":"United Kingdom","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.154,"area":"Bulgaria","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.108,"area":"Estonia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.062,"area":"Finland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.162,"area":"Malta","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":null}