{"orpha":398147,"name":"Persistent idiopathic facial pain","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["AFP","Atypical facial pain","PIFP"],"definition":"A rare neurological disease characterized by a generally deep, poorly localized, persistent facial pain that does not present characteristics of a cranial neuralgia and which cannot be attributed to another disorder.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-398147/","orphanet_url":"https://www.orpha.net/en/disease/detail/398147","names":{"fr":{"name":"Douleur faciale idiopathique persistante","synonyms":["AFP","Douleur faciale atypique","PIFP"],"definition":"Maladie neurologique rare caractérisée par une douleur faciale persistante, généralement profonde et difficilement localisable, qui ne présente pas les caractéristiques d'une névralgie crânienne et qui ne peut être attribuée à une autre maladie."},"de":{"name":"Persistierender idiopathischer Gesichtsschmerz","synonyms":["AFP","Gesichtsschmerz, atypischer","PIFP"],"definition":"Eine seltene neurologische Erkrankung, die durch einen im Allgemeinen tiefen, schlecht lokalisierten, anhaltenden Gesichtsschmerz gekennzeichnet ist, der keine Merkmale einer kranialen Neuralgie aufweist und nicht auf eine andere Störung zurückgeführt werden kann."},"es":{"name":"Dolor facial persistente idiopático","synonyms":["AFP","Dolor facial atípico","PIFP"],"definition":"Es una enfermedad neurológica poco frecuente caracterizada por dolor facial persistente, poco localizado y, por lo general, intenso que no presenta características de una neuralgia craneal y que no puede ser atribuido a ningún otro trastorno."},"it":{"name":"Dolore facciale idiopatico persistente","synonyms":["AFP","Dolore facciale atipico","PIFP"],"definition":"È una malattia neurologica rara, caratterizzata da dolore facciale persistente, di solito profondo e scarsamente localizzato, che non presenta le caratteristiche tipiche della nevralgia cranica e che non può essere ricondotto ad un'altra malattia."},"nl":{"name":"Persisterende idiopathische aangezichtspijn","synonyms":["AFP","Atypische aangezichtspijn","PIFP"],"definition":"Een zeldzame neurologische ziekte gekarakteriseerd door een doorgaans diepe, weinig gelokaliseerde, aanhoudende aangezichtspijn die geen kenmerken vertoont van een craniale neuralgie en die niet kan toegewezen worden aan een andere stoornis."},"pt":{"name":"Dor facial idiopática persistente"},"pl":{"name":"Przetrwały idiopatyczny ból twarzy","synonyms":["AFP","Atypowy ból twarzy","PIFP"]},"cs":{"name":"Perzistentní idiopatická bolest obličeje","synonyms":["AFP","PIFP","Atypická obličejová bolest"]},"uk":{"name":"Постійний ідіопатичний біль обличчя","synonyms":["AFP","Атиповий лицьовий біль","PIFP"],"definition":"A rare neurological disease characterized by a generally deep, poorly localized, persistent facial pain that does not present characteristics of a cranial neuralgia and which cannot be attributed to another disorder."},"zh":{"name":"持续性特发性面部疼痛","synonyms":["非典型性面部疼痛"],"definition":"本病是一种罕见的神经系统疾病，其特征是通常深部的、定位不良的、持续性的面部疼痛，不具有颅神经痛的特征，也不可被归因至其他疾病。"},"tr":{"name":"Kalıcı idiyopatik yüz ağrısı","synonyms":["AFP","PIFP","Atipik fasiyal ağrı"]}},"xrefs":[{"source":"ICD-10","code":"G50.1","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"8A85","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1799118131"},{"source":"MONDO","code":"0018362","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5191641","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":98006,"name":"Rare neurologic disease","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Lifetime Prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":30.0,"area":"Germany","status":"Validated","source":"21960648[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":4.4,"area":"Netherlands","status":"Validated","source":"19783099[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.0,"area":"Germany","status":"Validated","source":"12911872[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2024-07-10","source":"28251523[PMID]_28425324[PMID]_32992770[PMID]","terms":[{"hpo":"HP:0000271","label":"Abnormality of the face","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0012532","label":"Chronic pain","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0025282","label":"Dull","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0003489","label":"Acute episodes of neuropathic symptoms","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000739","label":"Anxiety","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0032143","label":"Burning mouth","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000716","label":"Depression","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0007328","label":"Impaired pain sensation","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003401","label":"Paresthesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003474","label":"Somatic sensory dysfunction","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0012639","label":"Abnormal nervous system morphology","frequency":"Excluded (0%)","criteria":null}]}}