{"orpha":391497,"name":"Juvenile myasthenia gravis","type":"Clinical subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":["Childhood myasthenia gravis","Juvenile acquired myasthenia","Juvenile autoimmune myasthenia gravis"],"definition":"Juvenile myasthenia gravis (MG) is a rare form of MG, an autoimmune disorder of the neuromuscular junction resulting in ocular manifestations or generalized weakness, with onset before 18 years of age.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-391497/","orphanet_url":"https://www.orpha.net/en/disease/detail/391497","names":{"fr":{"name":"Myasthénie auto-immune juvénile","synonyms":["Myasthenia gravis juvénile","Myasthénie acquise juvénile"],"definition":"Forme rare de myasthénie auto-immune (MG pour myasthenia gravis), une maladie auto-immune de la jonction neuromusculaire entraînant des manifestations oculaires ou une faiblesse généralisée, qui se manifeste avant l'âge de 18 ans."},"de":{"name":"Juvenile Myasthenia gravis","synonyms":["Juvenile autoimmune Myasthenia gravis","Myasthenia gravis der Kindheit","Myasthenie, erworbene, juvenile Form"],"definition":"Die juvenile Myasthenia gravis (MG; siehe dort) ist eine seltene Form der MG, eine Autoimmunerkrankung der neuromuskulären Verbindung, die zu okulären Manifestationen oder generalisierter Schwäche führt und vor dem Alter von 18 Jahren auftritt."},"es":{"name":"Miastenia grave juvenil","synonyms":["Miastenia grave autoinmune juvenil","Miastenia grave infantil","Miastenia juvenil adquirida"],"definition":"La miastenia grave juvenil (MG juvenil) es una forma poco frecuente de MG, un trastorno autoinmune de la unión neuromuscular, de inicio antes de los 18 años de edad, que provoca manifestaciones oculares o debilidad generalizada."},"it":{"name":"Miastenia gravis giovanile","synonyms":["Miastenia acquisita giovanile","Miastenia grave autoimmune giovanile","Miastenia gravis dell'infanzia"]},"nl":{"name":"Juveniele myasthenia gravis","synonyms":["Myasthenia gravis van de kindertijd","Juveniele auto-immune myasthenia gravis","Juveniele verworven myasthenie"],"definition":"Juveniele myasthenia gravis (MG; zie deze term) is een zeldzame vorm van MG, een auto-immuunziekte van de motorische eindplaat die leidt tot oculaire manifestaties of gegeneraliseerde spierzwakte, die aanvangt voor de leeftijd van 18 jaar."},"pt":{"name":"Miastenia gravis juvenil"},"pl":{"name":"Miastenia młodzieńcza","synonyms":["Autoimmunologiczna miastenia młodzieńcza","Miastenia dziecięca","Nabyta miastenia młodzieńcza"]},"cs":{"name":"Juvenilní myasthenia gravis","synonyms":["Juvenilní získaná myastenie","Juvenilní autoimunitní myasthenia gravis","Myastenia gravis dětského věku"]},"uk":{"name":"Ювенільна miastenia gravis","synonyms":["Дитяча міастенія","Ювенільна набута міастенія","Ювенільна аутоімунна міастенія"],"definition":"Juvenile myasthenia gravis (MG; see this term) is a rare form of MG, an autoimmune disorder of the neuromuscular junction resulting in ocular manifestations or generalized weakness, with onset before 18 years of age."},"zh":{"name":"青少年起病重症肌无力","synonyms":["青少年起病自身免疫性重症肌无力"],"definition":"青少年重症肌无力(MG;见本术语)是一种罕见的MG，是一种神经肌肉交界处的自身免疫性疾病，可导致眼部症状或全身无力，本病的发病年龄早于18岁。"},"tr":{"name":"Jüvenil myastenia gravis","synonyms":["Çocukluk çağı myastenia gravis","Jüvenil edinsel myastenia","Jüvenil otoimmün myastenia gravis"]}},"xrefs":[{"source":"ICD-10","code":"G70.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"8C60","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0018325","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680023","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":589,"name":"Myasthenia gravis","classifications":[181,189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Childhood","Infancy","Neonatal"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}