{"orpha":363746,"name":"Balint syndrome","type":"Clinical syndrome","group":"Disorder","status":"active","flags":[],"synonyms":["Balint-Holmes syndrome","Optic ataxia-gaze apraxia-simultanagnosia syndrome"],"definition":"Balint syndrome is a rare neurologic disease characterized by the triad of optic ataxia, ocular apraxia and simultanagnosia due to posterior parietal lobe lesions. Patients report ophthalmologic difficulties in the absence of underlying ophthalomologic anomalies and present severe visual and spatial disabilities in locating and reaching objects, initiating voluntary eye movements and perceiving more than one object at a time.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-363746/","orphanet_url":"https://www.orpha.net/en/disease/detail/363746","names":{"fr":{"name":"Syndrome de Balint","synonyms":["Syndrome d'ataxie optique-apraxie du regard-simultanagnosie","Syndrome de Balint-Holmes"],"definition":"Le syndrome de Balint est une maladie neurologique rare caractérisée par la triade d'ataxie optique, apraxie oculaire et simultanagnosie, due à des lésions du lobe pariétal postérieur. Les patients présentent des troubles ophtalmologiques en l'absence d'anomalie ophtalmologique sous-jacente, et présentent un déficit visuel sévère et de sévères difficultés pour localiser et atteindre des objets, pour initier des mouvements oculaires volontaires, et pour percevoir plus d'un objet à la fois."},"de":{"name":"Balint-Syndrom","synonyms":["Balint-Holmes-Syndrom","Optische Ataxie-okuläre Apraxie-Simultanagnosie-Syndrom"]},"es":{"name":"Síndrome de Balint","synonyms":["Síndrome de Balint-Holmes","Síndrome de ataxia óptica-apraxia ocular-simultagnosia"],"definition":"El síndrome de Balint es una enfermedad neurológica poco frecuente caracterizada por la tríada de ataxia óptica, apraxia ocular y simultanagnosia debida a lesiones del lóbulo parietal posterior. Los afectados presentan dificultades oftalmológicas en ausencia de anomalías oftalmológicas subyacentes, así como discapacidades visuales y espaciales graves para localizar y alcanzar objetos, iniciar movimientos oculares voluntarios y percibir más de un objeto a la vez."},"it":{"name":"Sindrome di Balint","synonyms":["Sindrome atassia ottica-aprassia dello sguardo-simultagnosia","Sindrome di Balint-Holmes"],"definition":"La sindrome di Balint è una malattia neurologica rara caratterizzata dalla triade atassia ottica, aprassia oculare e simultanagnosia secondaria a lesioni del lobo parietale posteriore. I pazienti presentano disturbi oculari in assenza di anomalie oculari, deficit visivi e spaziali gravi nel localizzare e afferrare gli oggetti, nell'attuazione dei movimenti volontari degli occhi e nella percezione simultanea di più oggetti."},"nl":{"name":"Syndroom van Balint","synonyms":["Optische ataxie - oculaire apraxie - simultaanagnosie-syndroom","Syndroom van Balint-Holmes"],"definition":"Syndroom van Balint is een zeldzame neurologische ziekte die gekarakteriseerd wordt door de triade van optische ataxie, oculaire apraxie en simultaanagnosie ten gevolge van laesies aan de posterieure pariëtale kwab. Patiënten melden oftalmologische problemen in afwezigheid van onderliggende oftalmologische anomalieën en vertonen ernstige visuele en ruimtelijke beperkingen bij het lokaliseren en grijpen van voorwerpen, het initiëren van vrijwillige oogbewegingen en het waarnemen van meer dan één voorwerp tegelijk."},"pt":{"name":"Síndrome de Balint"},"pl":{"name":"Zespół Balinta","synonyms":["Zespół ataksja optyczna-apraksja wzrokowa-symultanagnozja","Zespół Balinta i Holmesa"]},"cs":{"name":"Balintův syndrom","synonyms":["Syndrom zahrnující optickou ataxii, apraxii pohledu a simultanagnosii","Balintův-Holmesův syndrom","Balint-Holmesův syndrom"]},"uk":{"name":"Синдром Балінта","synonyms":["Синдром Балінта-Холмса","Синдром оптичної атаксії-апраксії погляду-симультанної акомодації"],"definition":"Balint syndrome is a rare neurologic disease characterized by the triad of optic ataxia, ocular apraxia and simultanagnosia due to posterior parietal lobe lesions. Patients report ophthalmologic difficulties in the absence of underlying ophthalomologic anomalies and present severe visual and spatial disabilities in locating and reaching objects, initiating voluntary eye movements and perceiving more than one object at a time."},"zh":{"name":"巴林特综合征","synonyms":["视觉共济失调-凝视失用症-同时性失认综合征"],"definition":"巴林特综合征是一种罕见的神经系统疾病，其特征为由后顶叶病变引起的视神经共济失调、眼球失用和同时性失认症三联征。在没有潜在眼科异常的情况下，患者报告存在眼科方面的障碍，并在定位和接触物体、启动自主眼球运动和同时感知多个物体方面存在严重的视觉和空间障碍。"},"tr":{"name":"Balint sendromu","synonyms":["Balint-Holmes sendromu","Optik ataksi-bakış apraksi-simultanagnozi sendromu"]}},"xrefs":[{"source":"ICD-10","code":"H51.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9C82.4","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"491228434"},{"source":"MONDO","code":"0018211","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4707368","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10057375","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":98006,"name":"Rare neurologic disease","classifications":[181]},{"orpha":519343,"name":"Rare ophthalmic disorder with cortical involvement","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"22999103[PMID]"}],"phenotypes":null}