{"orpha":36237,"name":"Bullous impetigo","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare, acquired, typically benign, bacterial infectious disease caused by <i>Staphylococcus aureus</i> characterized by large, fragile vesicles and flaccid bullae on an erythematous base, which evolve into moistened erosions with a thin, varnish-like crust, usually localized in intertriginous areas of the trunk and extremities (armpits, groins, between the fingers or toes, beneath the breasts). Although uncommon, systemic symptoms, such as fever, diarrhea, and weakness, may be associated.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-36237/","orphanet_url":"https://www.orpha.net/en/disease/detail/36237","names":{"fr":{"name":"Impétigo bulleux","definition":"Maladie infectieuse bactérienne rare, acquise et généralement bénigne, due au <i>Staphylococcus aureus</i> et caractérisée par de larges vésicules fragiles et par des bulles molles sur une peau érythémateuse, généralement localisées au niveau des zones intertrigineuses du tronc et des extrémités (aisselles, aine, entre les doigts et les orteils, sous les seins). Les lésions évoluent vers des érosions humides formant de fines croûtes qui ressemblent à du vernis. Bien que rares, des symptômes systémiques tels qu'une fièvre, une diarrhée et une faiblesse, peuvent être associés."},"de":{"name":"Impetigo, bullöse","definition":"Eine seltene, erworbene, typischerweise gutartige, bakterielle Infektionskrankheit, die durch <i>Staphylococcus aureus</i> verursacht wird und durch große, brüchige Bläschen und schlaffe Blasen auf erythematösem Grund gekennzeichnet ist, die sich zu befeuchteten Erosionen mit einer dünnen, lackartigen Kruste entwickeln. Die Läsionen sind gewöhnlich in intertriginösen Bereichen des Rumpfes und der Extremitäten (Achselhöhlen, Leisten, zwischen den Fingern oder Zehen, unter den Brüsten) lokalisiert. Obwohl selten, können systemische Symptome, wie Fieber, Durchfall und Schwäche, auftreten."},"es":{"name":"Impétigo ampolloso","synonyms":["Impétigo bulloso"],"definition":"Es una enfermedad infecciosa de origen bacteriano típicamente benigna, adquirida y poco frecuente, causada por <i>Staphylococcus aureus</i>. Está caracterizada por vesículas grandes y frágiles y ampollas flácidas en una base eritematosa que evolucionan a erosiones húmedas con una costra delgada tipo barniz, localizadas por lo general en áreas intertriginosas del tronco y las extremidades (axilas, ingles, entre los dedos de las manos y los pies, bajo los senos). Aunque sean poco frecuentes, síntomas sistémicos, como fiebre, diarrea y debilidad pueden ser asociados."},"it":{"name":"Impetigine bollosa","definition":"Si tratta di un'infezione batterica rara acquisita, di solito benigna, causata dallo <i>Staphylococcus aureus</i>. È caratterizzata dalla presenza di vescicole grandi e fragili, e di bolle flaccide su una base eritematosa, che evolvono in erosioni umide con una crosta sottile, che ha l'aspetto di una vernice. Di solito si localizzano sulle zone intertriginose del tronco e degli arti (ascelle, inguine, tra le dita delle mani e dei piedi, sotto le mammelle). Raramente si associa a sintomi sistemici, come la febbre, la diarrea e la debolezza."},"nl":{"name":"Bulleuze impetigo","definition":"Een zeldzame, verworven, doorgaans goedaardige, bacteriële infectieziekte veroorzaakt door <i>Staphylococcus aureus</i> en gekarakteriseerd door grote, fragiele vesikels en slappe blazen op een erythemateuze basis, die evolueren tot vochtige erosies met een dun, vernis-achtige korst, meestal gesitueerd in intertrigineuze gebieden van de romp en de ledematen (oksels, liezen, tussen de vingers of tenen, onder de borsten). Hoewel eerder zeldzaam kunnen systemische symptomen, zoals koorts, diarree, en zwakte, geassocieerd zijn."},"pt":{"name":"Impetigo bolhoso"},"pl":{"name":"Liszajec pęcherzowy"},"cs":{"name":"Bulózní impetigo"},"uk":{"name":"Бульозний імпетиго","definition":"A rare, acquired, typically benign, bacterial infectious disease caused by <i>Staphylococcus aureus</i> characterized by large, fragile vesicles and flaccid bullae on an erythematous base, which evolve into moistened erosions with a thin, varnish-like crust, usually localized in intertriginous areas of the trunk and extremities (armpits, groins, between the fingers or toes, beneath the breasts). Although uncommon, systemic symptoms, such as fever, diarrhea, and weakness, may be associated."},"zh":{"name":"大疱性脓疱疮"},"tr":{"name":"Büllöz impetigo"}},"xrefs":[{"source":"ICD-10","code":"L01.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1B72.0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1398484288"},{"source":"MONDO","code":"0018182","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1542647","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10006563","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":90077,"name":"Other acquired skin disease","classifications":[187]},{"orpha":300579,"name":"Staphylococcal toxemia","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0008066","label":"Abnormal blistering of the skin","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0010783","label":"Erythema","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0200039","label":"Pustule","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0005406","label":"Recurrent bacterial skin infections","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0100763","label":"Abnormality of the lymphatic system","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100820","label":"Glomerulopathy","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100806","label":"Sepsis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003095","label":"Septic arthritis","frequency":"Occasional (29-5%)","criteria":null}]}}