{"orpha":353356,"name":"Vasoproliferative tumor of the retina","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Retinal vasoproliferative tumor","VPTR","Vasoproliferative tumor of the ocular fundus"],"definition":"Vasoproliferative tumor of the retina is a rare, benign, retinal vascular disease characterized by solitary or multiple, unilateral or bilateral, intra-retinal tumor(s), usually located in the peripheral infero-temporal quadrant, and often associated with sub- and intraretinal exudates, epiretinal membranes, exudative retinal detachment and cystoid macular edema, as well as, occasionally, retinal and vitreous hemorrhage. Patients may present with visual loss, floaters, and/or photopsia. Association with various conditions, such as retinitis pigmentosa, congenital retinal toxoplasmosis, retinopathy of prematurity, or coloboma, has been reported.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-353356/","orphanet_url":"https://www.orpha.net/en/disease/detail/353356","names":{"fr":{"name":"Masses télangiectasiques périphériques","synonyms":["MTP","Tumeur vasoproliférative rétinienne","VPTR"],"definition":"Maladie vasculaire rare et bénigne de la rétine, caractérisée par une ou plusieurs tumeurs intra-rétiniennes solitaires ou multiples, unilatérales ou bilatérales, généralement situées dans le quadrant périphérique inférotemporal, et souvent associées à des exsudats sous- et intra-rétiniens, des membranes épirétiniennes, un décollement de rétine exsudatif et un oedème maculaire cystoïde, ainsi que, dans de rares cas, une hémorragie rétinienne et vitréenne. Une perte de vision, des corps flottants et/ou une photopsie peuvent s'observer. Des cas d'association avec diverses maladies, à savoir rétinite pigmentaire, toxoplasmose rétinienne congénitale, rétinopathie du prématuré ou colobome, ont été rapportés."},"de":{"name":"Vasoproliferativer Tumor der Retina","synonyms":["Tumor, retinaler vasoproliferativer","VPTR","Vasoproliferativer Tumor des okulären Fundus"]},"es":{"name":"Tumor vasoproliferativo de la retina","synonyms":["Tumor retiniano vasoproliferativo","Tumor vasoproliferativo del fondo de ojo","VPTR"],"definition":"El tumor vasoproliferativo de la retina es una enfermedad vascular retiniana, poco frecuente y benigna, caracterizada por un tumor intrarretiniano, uni- o bilateral, solitario o múltiple, generalmente localizado en el cuadrante infero-temporal periférico y asociado, a menudo, a exudados sub- e intrarretinianos, membranas epirretinianas, desprendimiento de retina exudativo y edema macular quístico, así como, ocasionalmente, hemorragia retiniana y vítrea. Los afectados pueden presentar pérdida visual, cuerpos flotantes y/o fotopsia. Se ha descrito asociación con diversas afecciones, tales como retinitis pigmentosa, toxoplasmosis retiniana congénita, retinopatía del prematuro o coloboma."},"it":{"name":"Tumore vasoproliferativo della retina","synonyms":["Tumore vasoproliferativo retinico","VPTR","Tumore vasoproliferativo del fondo oculare"],"definition":"Il tumore vasoproliferativo della retina è una malattia benigna rara dei vasi della retina, caratterizzata dalla presenza di uno o più tumori intra-retinici singoli o multipli, mono- o bilaterali, di solito localizzati nel quadrante infero-temporale periferico. Spesso si associa ad essudati sotto- e intraretinici, membrane epiretiniche, distacco essudativo della retina, edema maculare cistoide e, raramente, emorragia della retina e del cristallino. I pazienti possono presentare perdita della vista, miodesopsie e/o fotopsia. Può associarsi ad altre malattie, come la retinite pigmentosa, la toxoplasmosi retinica congenita, la retinopatia del prematuro e il coloboma."},"nl":{"name":"Vasoproliferatieve tumor van retina","synonyms":["Retinale vasoproliferatieve tumor","VPTR","Vasoproliferatieve tumor van netvlies","Vasoproliferatieve tumor van oogfundus"],"definition":"Vasoproliferatieve tumor van de retina is een zeldzame, goedaardige, retinale vasculaire ziekte die gekarakteriseerd wordt door een of meerdere, unilaterale of bilaterale, intraretinale tumor(en), meestal gesitueerd in het perifere inferotemporale kwadrant, en vaak geassocieerd met sub- en intraretinale exsudaten, epiretinale membranen, exsudatieve netvliesloslating en cystoïd macula-oedeem, alsook, occasioneel, retina- en glasvochtbloedingen. Patiënten vertonen mogelijk functieverlies van het zicht, glasvochttroebeling, en/of fotopsie. Associatie met verscheidene condities, zoals retinitis pigmentosa, congenitale retinale toxoplasmose, prematuren retinopathie of coloboom, werd reeds gerapporteerd."},"pt":{"name":"Tumor vasoproliferativo da retina"},"pl":{"name":"Wazoproliferacyjny guz siatkówki","synonyms":["Retinal vasoproliferative tumor","VPTR","Wazoproliferacyjny guz dna oka"]},"cs":{"name":"Vazoproliferativní nádor sítnice","synonyms":["Retinal vasoproliferative tumor","VPTR","Vasoproliferative tumor of the ocular fundus"]},"uk":{"name":"Вазопроліферативна пухлина сітківки","synonyms":["Вазопроліферативна пухлина сітківки","Вазопроліферативна пухлина очного дна","VPTR"],"definition":"Vasoproliferative tumor of the retina is a rare, benign, retinal vascular disease characterized by solitary or multiple, unilateral or bilateral, intra-retinal tumor(s), usually located in the peripheral infero-temporal quadrant, and often associated with sub- and intraretinal exudates, epiretinal membranes, exudative retinal detachment and cystoid macular edema, as well as, occasionally, retinal and vitreous hemorrhage. Patients may present with visual loss, floaters, and/or photopsia. Association with various conditions, such as retinitis pigmentosa, congenital retinal toxoplasmosis, retinopathy of prematurity, or coloboma, has been reported."},"zh":{"name":"视网膜血管增生性肿瘤","synonyms":["眼底血管增生性肿瘤"],"definition":"视网膜血管增殖性肿瘤是一种罕见的良性视网膜血管疾病，其特征为单眼或多发、单侧或双侧视网膜内肿瘤，通常位于外周颞下象限，常伴有视网膜下和视网膜内渗出物、视网膜前膜、渗出性视网膜脱离和黄斑囊样水肿，偶尔还会伴有视网膜和玻璃体出血。患者可能出现视力丧失、飞蚊症和/或光视。本病与多种疾病的关联已有报道，如视网膜色素变性、先天性视网膜弓形虫病、早产儿视网膜病变或缺损。"},"tr":{"name":"Retinanın vazoproliferatif tümörü","synonyms":["VPTR","Retinal vazoproliferatif tümör","Oküler fundusun vazoproliferatif tümörü"]}},"xrefs":[{"source":"ICD-10","code":"D31.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2F36.Y","qualifier":"NTBT","icd_relation":"attributed","validated":true,"icd11_uri":"null"},{"source":"MONDO","code":"0018148","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4749792","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":71281,"name":"Rare central nervous system and retinal vascular disease","classifications":[181]},{"orpha":101950,"name":"Rare eye tumor","classifications":[189,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":[],"prevalence":[],"phenotypes":null}