{"orpha":352636,"name":"Phalangeal microgeodic syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Phalangeal osteolysis"],"definition":"A rare primary osteolysis disorder characterized by multiple small osteolytic areas and sclerosis in the phalanges of one or both hands associated with swelling and redness of the phalanges. Condition is benign, self-limited and may be associated with cold exposure.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-352636/","orphanet_url":"https://www.orpha.net/en/disease/detail/352636","names":{"fr":{"name":"Syndrome microgéodique des phalanges","synonyms":["Ostéolyse phalangienne"],"definition":"Ostéolyse primaire rare caractérisée par de multiples petites zones ostéolytiques et une sclérose affectant les phalanges d'une ou des deux mains associées à un gonflement et à une rougeur des phalanges. Bénigne et spontanément résolutive, la maladie peut être associée à une exposition au froid."},"de":{"name":"Transitorische Osteolyse der Phalangen","synonyms":["Phalangeale Osteolyse"]},"es":{"name":"Síndrome falángico microgeódico","synonyms":["Acroosteólisis falángica"],"definition":"Es una osteólisis primaria poco frecuente caracterizada por múltiples zonas osteolíticas pequeñas y esclerosis de las falanges de una o ambas manos, así como edema y enrojecimiento de las falanges. La afección es benigna, autolimitada y puede estar relacionada con la exposición al frío."},"it":{"name":"Sindrome microgeodica falangea","synonyms":["Osteolisi falangea"],"definition":"La sindrome microgeodica falangea è un'osteolisi primitiva rara, caratterizzata da piccole aree osteolitiche multiple e sclerosi delle falangi di una o di entrambe le mani, con tumefazione e rossore delle falangi. La malattia è benigna ed autolimitante; può essere collegata con l'esposizione al freddo."},"nl":{"name":"Falangeaal microgeodisch syndroom","synonyms":["Falangeale osteolyse"],"definition":"Een zeldzame, primaire osteolyse, gekarakteriseerd door meervoudige kleine osteolytische gebieden en sclerose in falangen van een of beide handen, geassocieerd met zwelling en roodheid van falangen. De conditie is goedaardig en zelfbeperkend, en kan geassocieerd zijn met blootstelling aan koude."},"pt":{"name":"Síndrome de falanges micro geodésicas"},"pl":{"name":"Phalangeal microgeodic syndrome","synonyms":["Osteoliza paliczków"]},"cs":{"name":"Falangeální osteolýza","synonyms":["Falangeální mikrogeodický syndrom"]},"uk":{"name":"Фаланговий мікрогеодичний синдром","synonyms":["Остеоліз фалангових кісток"],"definition":"A rare primary osteolysis disorder characterized by multiple small osteolytic areas and sclerosis in the phalanges of one or both hands associated with swelling and redness of the phalanges. Condition is benign, self-limited and may be associated with cold exposure."},"zh":{"name":"指骨小晶洞病综合征","synonyms":["指骨溶解症"],"definition":"本病是一种罕见的原发性溶骨性疾病，其特征是单手或双手指骨出现多个小溶骨区和硬化，并伴有指骨肿胀和发红。这种情况是良性及自限性的，可能与寒冷暴露有关。"},"tr":{"name":"Falangeal mikrojeodik sendrom","synonyms":["Falanjiyal osteoliz"]}},"xrefs":[{"source":"ICD-10","code":"M89.5","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"FB86.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0018128","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4749465","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93419,"name":"Rare bone disease"},"parents":[{"orpha":93449,"name":"Primary osteolysis","classifications":[147,156,199]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Childhood"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":50.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}