{"orpha":3343,"name":"Toxocariasis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A cosmopolitan zoonotic disease caused in humans by the accidental ingestion of eggs or larvae of the ascarids <i>Toxocara canis</i> or <i>Toxocara cati</i>, the common round worm of dogs and cats respectively. The infestation can be asymptomatic or can present as visceral larva migrans caused by larval migration through major organs such as liver, lungs or central nervous system (manifesting with fever, cough, hepatomegaly, pneumonia or rarely encephalitis), or as ocular larva migrans caused by larval migration to the eye (manifesting as ocular inflammation and retinal scaring).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-3343/","orphanet_url":"https://www.orpha.net/en/disease/detail/3343","names":{"fr":{"name":"Toxocarose","definition":"Zoonose cosmopolite provoquée chez l'homme par l'ingestion accidentelle d'oeufs ou de larves des ascarides <i>Toxocara canis</i> ou <i>Toxocara cati</i>, le ver rond commun chez les chiens et les chats. L'infestation peut être asymptomatique ou se présenter sous la forme d'une larva migrans viscérale causée par la migration des larves dans les principaux organes, tels que le foie, les poumons ou le système nerveux central (se manifestant par une fièvre, une toux, une hépatomégalie, une pneumonie ou, dans de rares cas, par une encéphalite), ou sous la forme d'une larva migrans oculaire causée par la migration des larves dans l'oeil (se manifestant par une inflammation oculaire et des cicatrices rétiniennes)."},"de":{"name":"Toxocariasis","definition":"Die Toxocariasis ist eine weltweit verbreitete Parasitose, die beim Menschen durch die versehentliche Aufnahme von Eiern oder Larven der Askariden <i>Toxocara canis</i> oder <i>Toxocara cati</i>, dem häufigsten Rundwurm von Hunden bzw. Katzen, verursacht wird. Der Befall kann asymptomatisch sein oder durch Larvenwanderung im Körper die inneren Organe betreffen (viszerale Larva migrans) und Leber, Lunge oder zentrales Nervensystem (mit Fieber, Husten, Hepatomegalie, Lungenentzündung oder seltener Enzephalitis) schädigen, oder in Form der okulären Larva migrans mit Augenentzündung und Netzhautvergrößerung einhergehen."},"es":{"name":"Toxocariasis","definition":"Es una enfermedad zoonótica cosmopolita causada en humanos por la ingestión accidental de huevos o larvas de los ascáridos <i>Toxocara canis</i> o <i>Toxocara cati</i>, el gusano redondo común de perros y gatos, respectivamente. La infestación puede ser asintomática o presentarse como larva migrans visceral causada por la migración de larvas a través de órganos principales tales como el hígado, los pulmones o el sistema nervioso central (que se manifiesta con fiebre, tos, hepatomegalia, neumonía y, raramente, con encefalitis) o como larva migrans ocular causada por la migración de larvas hacia el ojo (que se manifiesta con inflamación ocular y cicatrización retiniana)."},"it":{"name":"Toxocariasi","definition":"La toxocariasi è una zoonosi cosmopolita, causata nell'uomo dall'ingestione accidentale di uova o di larve di ascaridi <i>Toxocara canis</i> o <i>Toxocara cati</i>, i vermi comuni tondi, rispettivamente dei cani e dei gatti. La malattia può essere asintomatica oppure manifestarsi come larva viscerale migrante, causata dalla migrazione delle larve attraverso i principali organi come il fegato, i polmoni o il sistema nervoso centrale (che si manifesta clinicamente con febbre, tosse, epatomegalia, polmonite e, raramente, encefalite), oppure come larva migrante oculare, causata dalla migrazione delle larve nell'occhio (che si manifesta con infiammazione oculare e formazione di cicatrici retiniche)."},"nl":{"name":"Toxocariasis","synonyms":["Infectie door Toxocara"],"definition":"Een kosmopolitische zoönose die bij mensen wordt veroorzaakt door onopzettelijke inname van eieren of larven van de Ascariden <i>Toxocara canis</i> or <i>Toxocara cati</i>, de meest voorkomende spoelwormen bij respectievelijk honden en katten. De besmetting kan asymptomatisch zijn, of voorkomen als viscerale larva migrans veroorzaakt door migratie van larven door belangrijke organen zoals lever, longen of centraal zenuwstelsel (met manifestaties als koorts, hoest, hepatomegalie, pneumonie of in zeldzamere gevallen encefalitis), of als oculaire larva migrans veroorzaakt door migratie van larven door het oog (met manifestaties als oogontsteking en littekenvorming op het netvlies)."},"pt":{"name":"Toxocariose"},"pl":{"name":"Toksokaroza"},"cs":{"name":"Toxokaróza"},"uk":{"name":"Токсокароз","definition":"A cosmopolitan zoonotic disease caused in humans by the accidental ingestion of eggs or larvae of the ascarids <i>Toxocara canis</i> or <i>Toxocara cati</i>, the common round worm of dogs and cats respectively. The infestation can be asymptomatic or can present as visceral larva migrans caused by larval migration through major organs such as liver, lungs or central nervous system (manifesting with fever, cough, hepatomegaly, pneumonia or rarely encephalitis), or as ocular larva migrans caused by larval migration to the eye (manifesting as ocular inflammation and retinal scaring)."},"zh":{"name":"弓蛔虫病"},"tr":{"name":"Toksokariyaz"}},"xrefs":[{"source":"ICD-10","code":"B83.0","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1F6D","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1794729263"},{"source":"MONDO","code":"0005988","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D014120","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0040553","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10044269","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163588,"name":"Rare parasitic disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Childhood"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":3.3,"area":"United States","status":"Not yet validated","source":"emedicine[OTHER]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}