{"orpha":3221,"name":"Generalized resistance to thyroid hormone","type":"Disease","group":"Disorder","status":"inactive","flags":["Deprecated entity"],"synonyms":["Deafness-thyroid hormone resistance syndrome","Hearing loss-thyroid hormone resistance syndrome","Refetoff syndrome"],"definition":null,"note":"This entity has been excluded from the Orphanet nomenclature of rare diseases and moved to Resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta","url":"https://raremap.alftech.space/d/ORPHA-3221/","orphanet_url":"https://www.orpha.net/en/disease/detail/3221","names":{"fr":{"name":"Résistance généralisée aux hormones thyroïdiennes","synonyms":["Syndrome de Refetoff"]},"de":{"name":"Generalisierte Resistenz gegen Schilddrüsenhormone","synonyms":["Refetoff-Syndrom","Schwerhörigkeit - Resistenz gegen Schilddrüsenhormone"]},"es":{"name":"Resistencia generalizada a la hormona tiroidea","synonyms":["Síndrome de hipoacusia-resistencia a la hormona tiroidea","Síndrome de sordera-resistencia a la hormona tiroidea"]},"it":{"name":"Resistenza generalizzata all'ormone tiroideo","synonyms":["Sindrome di Refetoff","Sordità - resistenza all'ormone tiroideo"]},"nl":{"name":"Gegeneraliseerde resistentie tegen schildklierhormoon","synonyms":["Doofheid - schildklierhormoonresistentie-syndroom","Gehoorverlies - schildklierhormoonresistentie-syndroom","Syndroom van Refetoff"]},"pt":{"name":"Resistência à hormona tiroideia generalizada","synonyms":["Síndrome Refetoff","Síndrome de perda auditiva-resistência à hormona tiroideia"]},"pl":{"name":"Uogólniona oporność na hormony tarczycy","synonyms":["Głuchota - oporność na hormony tarczycy","Zespół Refetoffa"]},"cs":{"name":"Generalizovaná rezistence vůči thyreoidálním hormonům","synonyms":["Syndrom zahrnující hluchotu a rezistenci vůči thyreoidálním hormonům","Refetoffův syndrom"]},"uk":{"name":"Генералізована резистентність до гормонів щитовидної залози","synonyms":["Синдром глухоти - резистентності до гормонів щитовидної залози","Синдром резистентності до гормонів щитовидної залози та втрата слуху","Синдром Рефетова"]},"zh":{"name":"全身性甲状腺激素抵抗","synonyms":["听力丧失-甲状腺激素抵抗综合征"]},"tr":{"name":"Tiroid hormonuna jeneralize direnç","synonyms":["Refetoff sendromu","Sağırlık-tiroid hormonu direnci sendromu","İşitme kaybı-tiroid hormonu direnci sendromu"]}},"xrefs":[{"source":"GARD","code":"301","qualifier":"E","icd_relation":null,"validated":true}],"associations":[{"type":"Moved to","orpha":566243,"name":"Resistance to thyroid hormone due to a mutation in thyroid hormone receptor beta"}],"incoming_associations":[],"preferential_parent":null,"parents":[],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}