{"orpha":314786,"name":"Silent pituitary adenoma","type":"Histopathological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-314786/","orphanet_url":"https://www.orpha.net/en/disease/detail/314786","names":{"fr":{"name":"Adénome hypophysaire silencieux"},"de":{"name":"Hypophysenadenom, stummes","synonyms":["Hypophysenadenom, hormoninaktives"]},"es":{"name":"Adenoma hipofisario silente"},"it":{"name":"Adenoma ipofisario silente"},"nl":{"name":"Stil hypofyseadenoom"},"pt":{"name":"Adenoma hipofisário silencioso"},"pl":{"name":"Cichy gruczolak przysadki"},"cs":{"name":"Tichý adenom hypofýzy"},"uk":{"name":"Тиха аденома гіпофіза"},"zh":{"name":"无症状垂体腺瘤"},"tr":{"name":"Sessiz hipofiz adenomu"}},"xrefs":[{"source":"ICD-10","code":"D35.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0017825","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97978,"name":"Rare endocrine disease"},"parents":[{"orpha":91349,"name":"Non-functioning pituitary adenoma","classifications":[193,202]}],"children":[],"genes":[{"symbol":"AIP","name":"AHR interacting HSP90 co-chaperone","gene_type":"gene with protein product","association":"Major susceptibility factor in","status":"Assessed","source":"23321498[PMID]","hgnc":"358","ensembl":"ENSG00000110711","omim":"605555","loci":["11q13.2"]},{"symbol":"MEN1","name":"menin 1","gene_type":"gene with protein product","association":"Major susceptibility factor in","status":"Assessed","source":"23321498[PMID]","hgnc":"7010","ensembl":"ENSG00000133895","omim":"613733","loci":["11q13.1"]}],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":[],"prevalence":[],"phenotypes":null}