{"orpha":313920,"name":"Epstein-Barr virus-associated gastric carcinoma","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["EBV-associated gastric carcinoma","EBVaGC"],"definition":"A rare form of gastric carcinoma characterized by a latent EBV infection in gastric carcinoma cells, diffuse-type histology, a proximal location (in the body and cardia of the stomach) and a relatively favorable prognosis.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-313920/","orphanet_url":"https://www.orpha.net/en/disease/detail/313920","names":{"fr":{"name":"Carcinome gastrique associé au virus Epstein-Barr","synonyms":["Carcinome gastrique associé à l'EBV","EBVaGC"],"definition":"Forme rare de carcinome gastrique caractérisée par une infection par l'EBV latente des cellules de carcinome gastrique, de type histologique diffus, une localisation proximale (dans le corps et le cardia de l'estomac) et un pronostic relativement favorable."},"de":{"name":"Epstein-Barr Virus-assoziiertes Magenkarzinom","synonyms":["EBVaGC","Magenkrebs, EBV-assoziierter"],"definition":"Eine seltene Form des Magenkarzinoms, die durch eine latente EBV-Infektion in Magenkarzinomzellen, eine diffuse Histologie, eine proximale Lage (im Körper und in der Kardia des Magens) und eine relativ günstige Prognose gekennzeichnet ist."},"es":{"name":"Carcinoma gástrico asociado al virus de Epstein-Barr","synonyms":["Carcinoma gástrico asociado a EBV","EBVaGC"],"definition":"Es una forma de carcinoma gástrico poco frecuente caracterizado por una infección latente de VEB en células de carcinoma gástrico, con histología de tipo difuso, localización proximal (en el cuerpo y cardias del estómago) y un pronóstico relativamente favorable."},"it":{"name":"Carcinoma gastrico associato al virus di Epstein-Barr","synonyms":["Carcinoma gastrico EBV-associato","EBVaGC"],"definition":"Il carcinoma gastrico associato al virus di Epstein-Barr (EBVaGC) è un carcinoma gastrico raro (presente in circa il 10% dei casi), che colpisce soprattutto i maschi. È caratterizzato da un'infezione latente da virus di Epstein-Barr (EBV) nelle cellule del carcinoma gastrico, presenta un'istologia diffusa, una localizzazione prossimale (nel corpo e nel cardias dello stomaco) ed ha una prognosi relativamente favorevole."},"nl":{"name":"Epstein-Barrvirus-geassocieerd gastrisch carcinoom","synonyms":["EBV-geassocieerd gastrisch carcinoom","EBVaGC"],"definition":"Een zeldzame vorm van carcinoom van maag, gekenmerkt door latente EBV-infectie van gastrische carcinoomcellen, diffuus-type histologie, proximale locatie (in corpus (lichaam) en cardia (ingang) van maag) en relatief gunstige prognose."},"pt":{"name":"Carcinoma gástrico associado a vírus Epstein-Barr","synonyms":["Carcinoma gástrico associado a EBV","EBVaGC"]},"pl":{"name":"Rak żołądka związany z wirusem Epsteina i Barra","synonyms":["EBVaGC","Rak żołądka związany z EBV"]},"cs":{"name":"Karcinom žaludku asociovaný s virem Epsteina-Barrové","synonyms":["EBV-asociovaný karcinom žaludku","EBVaGC","Karcinom žaludku asociovaný s virem Epstein-Barrové"]},"uk":{"name":"Епштейн-Барр-асоційована карцинома шлунка","synonyms":["EBVaGC","EBV-асоційована карцинома шлунка"],"definition":"A rare form of gastric carcinoma characterized by a latent EBV infection in gastric carcinoma cells, diffuse-type histology, a proximal location (in the body and cardia of the stomach) and a relatively favorable prognosis."},"zh":{"name":"EB病毒相关性胃癌","synonyms":["EBV相关性胃癌"],"definition":"EB病毒相关性胃癌（EBVaGC）是一种罕见的胃癌（约10%的病例），多见于男性，其特征是胃癌细胞内潜伏EBV感染，组织学上呈弥漫型，多发生于近端位置（胃体和贲门处），其预后相对较好。"},"tr":{"name":"Epstein-Barr virüsü -ilişkili mide karsinomu","synonyms":["EBVaGC","EBV-ilişkili mide karsinomu"]}},"xrefs":[{"source":"ICD-10","code":"C16.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"C16.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2B72.Y","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0017784","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4274414","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":289651,"name":"Epstein-Barr Virus-associated carcinoma","classifications":[202]},{"orpha":423771,"name":"Rare carcinoma of stomach","classifications":[152,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Multigenic/multifactorial"],"onset":["Adult","Elderly"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.2,"area":"Worldwide","status":"Not yet validated","source":"22392024[PMID]_ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}