{"orpha":31202,"name":"Melioidosis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Burkholderia pseudomallei infection"],"definition":"A tropical infectious disease caused by the Gram-negative bacterium <i>Burkholderia pseudomallei</i>, which is present in soil and water in tropical countries. Melioidosis can present itself in many ways, including pneumonia, sepsis and abscess formation.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-31202/","orphanet_url":"https://www.orpha.net/en/disease/detail/31202","names":{"fr":{"name":"Mélioïdose","synonyms":["Infection à Burkholderia pseudomallei"],"definition":"Maladie infectieuse tropicale causée par un baccile à Gram-négatif <i>Burkholderia pseudomallei</i>, présent dans le sol et l'eau des pays tropicaux. La mélioïdose peut se manifester de différentes manières, notamment par une pneumonie, une septicémie et la formation d'abcès."},"de":{"name":"Melioidose","synonyms":["Burkholderia-pseudomallei-Infektion","Pseudorotz"],"definition":"Eine seltene Infektionskrankheit, die durch das gramnegative Bakterium <i>Burkholderia pseudomallei</i> verursacht wird, das in tropischen Ländern im Boden und im Wasser vorkommt. Melioidose kann sich auf verschiedene Weise äußern, darunter Lungenentzündung, Sepsis und Abszessbildung."},"es":{"name":"Melioidosis","synonyms":["Infección por Burkholderia pseudomallei"],"definition":"Es una enfermedad infecciosa tropical causada por la bacteria Gram negativa <i>Burkholderia pseudomallei</i>, que está presente en el suelo y el agua de países tropicales. La melioidosis puede manifestarse de muchas formas, incluyendo neumonía, sepsis y formación de abscesos."},"it":{"name":"Melioidosi","synonyms":["Infezione da Burkholderia pseudomallei"],"definition":"La melioidosi è una malattia infettiva rara, causata dal bacillo gram-negativo Burkholderia (pseudomonas) pseudomallei, noto anche come bacillo di Whitmore. L'infezione, che può essere acuta, subacuta o cronica, interessa la cute, i polmoni, o l'intero organismo."},"nl":{"name":"Melioïdose","synonyms":["Infectie door Burkholderia pseudomallei","Melioidosis"],"definition":"Een tropische infectieuze aandoening, veroorzaakt door de Gram-negatieve bacterie <i>Burkholderia pseudomallei</i>, die aanwezig is in bodem en water in tropische landen. Melioïdose kan zich op vele manieren manifesteren, onder meer met pneumonie, sepsis en vorming van abces."},"pt":{"name":"Melioidose","definition":"Doença infeciosa tropical causada pela bactéria Gram-negativa <i>Burkholderia pseudomallei</i>, que está presente no solo e na água de países tropicais. A melioidose pode apresentar-se de várias formas, incluindo pneumonia, sépsis e formação de abcessos."},"pl":{"name":"Melioidoza","synonyms":["Burkholderia pseudomallei infection"]},"cs":{"name":"Melioidóza","synonyms":["Burkholderia pseudomallei infection"]},"uk":{"name":"Меліоїдоз","definition":"A tropical infectious disease caused by the Gram-negative bacterium <i>Burkholderia pseudomallei</i>, which is present in soil and water in tropical countries. Melioidosis can present itself in many ways, including pneumonia, sepsis and abscess formation."},"zh":{"name":"类鼻疽"},"tr":{"name":"Melioidoz"}},"xrefs":[{"source":"OMIM","code":"615557","qualifier":"BTNT","icd_relation":null,"validated":true},{"source":"ICD-10","code":"A24.1","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"A24.2","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"A24.3","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"A24.4","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1C42","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"2129350166"},{"source":"MONDO","code":"0017775","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D008554","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0025229","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"9546","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10069748","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163582,"name":"Rare bacterial infectious disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"},{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":50.0,"area":"Australia","status":"Validated","source":"22970946[PMID]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-5 / 10 000","value":50.0,"area":"Thailand","status":"Validated","source":"22970946[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2019-11-18","source":"27423906[PMID]_29388572[PMID]","terms":[{"hpo":"HP:0011949","label":"Acute infectious pneumonia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031864","label":"Bacteremia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001945","label":"Fever","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0025044","label":"Lung abscess","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002090","label":"Pneumonia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0011947","label":"Respiratory tract infection","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100806","label":"Sepsis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031273","label":"Shock","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001743","label":"Abnormality of the spleen","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030049","label":"Brain abscess","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100658","label":"Cellulitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0031292","label":"Cutaneous abscess","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012115","label":"Hepatitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100523","label":"Liver abscess","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002758","label":"Osteoarthritis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0003095","label":"Septic arthritis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025059","label":"Splenic abscess","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0032162","label":"Unusual skin infection","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000197","label":"Abnormal parotid gland morphology","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000119","label":"Abnormality of the genitourinary system","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0001886","label":"Foot osteomyelitis","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0011850","label":"Parotitis","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000024","label":"Prostatitis","frequency":"Very rare (<4-1%)","criteria":null}]}}