{"orpha":295034,"name":"Congenital knee dislocation","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare congenital limb malformation characterized by either hyperextension of the knee greater than 0° associated with limited flexion (congenital genu recurvatum) or permanent knee flexion with limited extension (congenital genu flexum). It can be unilateral or bilateral and may occur as an isolated malformation, be associated with other orthopedic abnormalities (like developmental dysplasia of the hip or clubfoot), or be part of a syndrome (e. g. Larsen's syndrome, arthrogryposis multiplex congenita).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-295034/","orphanet_url":"https://www.orpha.net/en/disease/detail/295034","names":{"fr":{"name":"Luxation congénitale du genou","definition":"Anomalie congénitale rare des membres caractérisée soit par une hyperextension du genou supérieure à 0° associée à une flexion limitée (genu recurvatum congénital) soit par une flexion permanente du genou accompagnée d'une extension limitée (genu flexum congénital). Unilatérale ou bilatérale, l'anomalie peut être isolée, associée à d'autres anomalies orthopédiques (telles qu'une dysplasie développementale de la hanche ou un pied bot) ou être l'une des manifestations d'un syndrome (par exemple, le syndrome de Larsen ou l'arthrogrypose multiple congénitale)."},"de":{"name":"Kniedislokation, kongenitale","definition":"Eine seltene angeborene Fehlbildung der Extremitäten, die entweder durch eine Überstreckung des Knies von mehr als 0° in Verbindung mit einer eingeschränkten Beugung (kongenitales Genu recurvatum) oder durch eine permanente Kniebeugung mit eingeschränkter Streckung (kongenitales Genu flexum) gekennzeichnet ist. Sie kann ein- oder beidseitig sein und als isolierte Fehlbildung auftreten, mit anderen orthopädischen Anomalien (wie Entwicklungsdysplasie der Hüfte oder Klumpfuß) einhergehen oder Teil eines Syndroms sein (z. B. Larsen-Syndrom, Arthrogryposis multiplex congenita)."},"es":{"name":"Luxación congénita de la rodilla","definition":"Es una malformación congénita poco frecuente de las extremidades caracterizada bien por una hiperextensión de la rodilla superior a 0° con limitación de la flexión (<i>genu recurvatum</i> congénito) o bien por una flexión permanente de la rodilla con una limitación de la extensión (<i>genu flexum</i> congénito). Puede ser uni- o bilateral y puede presentarse como una malformación aislada, asociada a otras anomalías ortopédicas (tales como displasia del desarrollo de la cadera o pie zambo) o formando parte de un síndrome (p. ej. síndrome de Larsen, artrogriposis múltiple congénita)."},"it":{"name":"Dislocazione congenita del ginocchio","definition":"Si tratta di una malformazione congenita rara degli arti, caratterizzata dall'iperestensione del ginocchio superiore a 0° associata alla limitazione della flessione (genu recurvatum congenito), oppure da una flessione permanente del ginocchio con estensione limitata (genu flexum congenito). Può essere monolaterale o bilaterale, isolata o associata ad altre anomalie ortopediche (displasia dello sviluppo dell'anca o piedi torti), oppure rientrare nel quadro clinico di una sindrome (ad es. la sindrome di Larsen o l'artrogriposi multipla congenita)."},"nl":{"name":"Congenitale knieluxatie","definition":"Een zeldzame, congenitale ledemaatmalformatie, gekarakteriseerd door ofwel hyperextensie van de knie voorbij 0° geassocieerd met beperkte flexie (congenitale genu recurvatum), ofwel permanente flexie van de knie met beperkte extensie (congenitale genu flexum). Het kan unilateraal of bilateraal zijn, en kan als een geïsoleerde malformatie voorkomen, geassocieerd zijn met andere orthopedische afwijkingen (zoals congenitale heupdysplasie of klompvoet) of deel uitmaken van een syndroom (e.g. syndroom van Larsen, arthrogryposis multiplex congenita). syndroom van Larsen, arthrogryposis multiplex congenita)."},"pt":{"name":"Luxação congénita do joelho"},"pl":{"name":"Wrodzone zwichnięcie stawu kolanowego"},"cs":{"name":"Vrozená dislokace kolena"},"uk":{"name":"Вроджений вивих колінного суглоба","definition":"A rare congenital limb malformation characterized by either hyperextension of the knee greater than 0° associated with limited flexion (congenital genu recurvatum) or permanent knee flexion with limited extension (congenital genu flexum). It can be unilateral or bilateral and may occur as an isolated malformation, be associated with other orthopedic abnormalities (like developmental dysplasia of the hip or clubfoot), or be part of a syndrome (e. g. Larsen's syndrome, arthrogryposis multiplex congenita)."},"zh":{"name":"先天性膝关节脱位","definition":"一种罕见的先天性肢体畸形，其特征是膝关节过度伸展大于0 sup U+2591 inf 并屈曲受限（先天性膝外翻）或永久性膝关节屈曲受限（先天性膝屈肌）。可为单侧或双侧，可为孤立性畸形，与其他骨异常（如髋或马蹄内翻足发育不良）有关，也可以是综合征的一部分（如Larsen氏综合症、先天性多发性关节炎）。"},"tr":{"name":"Doğumsal diz çıkığı"}},"xrefs":[{"source":"ICD-10","code":"Q68.2","qualifier":"NTBT","icd_relation":"inclusion","validated":true},{"source":"ICD-11","code":"LB93","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1229590493"},{"source":"MONDO","code":"0017470","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0265669","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10010520","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":294951,"name":"Congenital joint dislocations","classifications":[147,156]}],"children":[{"orpha":295232,"name":"Congenital genu flexum","type":"Clinical subtype"},{"orpha":295229,"name":"Congenital genu recurvatum","type":"Clinical subtype"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}