{"orpha":295004,"name":"Central polydactyly","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":["Mesoaxial polydactyly"],"definition":"A rare congenital limb malformation characterized by complete or partial duplication of one of the three middle digits in a hand or foot. It most commonly affects the fourth digit. The malformation may be unilateral or bilateral and can occur as an isolated defect or in association with other anomalies.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-295004/","orphanet_url":"https://www.orpha.net/en/disease/detail/295004","names":{"fr":{"name":"Polydactylie centrale","synonyms":["Polydactylie mésoaxiale"],"definition":"Malformation congénitale des membres rare caractérisée par la duplication complète ou partielle de l'un des trois doigts ou orteils. Le quatrième doigt est le plus souvent touché. La malformation peut être unilatérale ou bilatérale et apparaître isolée ou associée à d'autres malformations."},"de":{"name":"Zentrale Polydaktylie","synonyms":["Mesoaxiale Polydaktylie"],"definition":"Eine seltene angeborene Fehlbildung der Extremitäten, die durch eine vollständige oder teilweise Verdoppelung eines der drei mittleren Gliedmaßen einer Hand oder eines Fußes gekennzeichnet ist. Am häufigsten ist der vierte Finger betroffen. Die Fehlbildung kann ein- oder beidseitig sein und kann als isolierter Defekt oder in Verbindung mit anderen Anomalien auftreten."},"es":{"name":"Polidactilia central","synonyms":["Polidactilia en espejo","Polidactilia mesoaxial"],"definition":"Es una malformación congenita poco frecuente de las extremidades caracterizada por la duplicación completa o parcial de uno de los tres dedos del medio de la mano o del pie, afectando con mayor frecuencia al cuarto dígito. La malformación puede ser uni- o bilateral, presentándose como un defecto aislado o asociado a otras anomalías."},"it":{"name":"Polidattilia centrale","synonyms":["Mano a specchio","Polidattilia centrale della mano","Polidattilia mesoassiale delle dita delle mani"],"definition":"Si tratta di una malformazione congenita rara degli arti, caratterizzata dalla duplicazione completa o parziale di una delle tre dita centrali della mano o del piede. Il quarto dito è quello più comunemente interessato. La malformazione può essere monolaterale o bilaterale, isolata o associata ad altre anomalie."},"nl":{"name":"Centrale polydactylie","synonyms":["Mesoaxiale polydactylie"],"definition":"Een zeldzame congenitale malformatie van ledemaat, gekarakteriseerd door volledige of gedeeltelijke duplicatie van een van de drie middelste digiti van hand of voet. Doorgaans wordt de vierde digitus getroffen. De malformatie kan unilateraal of bilateraal zijn, en als geïsoleerd defect of in associatie met andere anomalieën voorkomen."},"pt":{"name":"Polidactilia central dos dedos da mão","synonyms":["Mão em espelho","Polidactilia central da mão","Polidactilia mesoaxial dos dedos da mão"]},"pl":{"name":"Polidaktylia centralna palców","synonyms":["Dłoń lustrzana","Mezoaksjalna (centralna) polidaktylia palców ręki","Polidaktylia centralna dłoni"]},"cs":{"name":"Centrální polydaktylie prstů ruky","synonyms":["Centrální polydaktylie ruky","Zrcadlová ruka","Mesoaxiální polydaktylie prstů ruky"]},"uk":{"name":"Центральна полідактилія","synonyms":["Мезоаксіальна полідактилія"],"definition":"A rare congenital limb malformation characterized by complete or partial duplication of one of the three middle digits in a hand or foot. It most commonly affects the fourth digit. The malformation may be unilateral or bilateral and can occur as an isolated defect or in association with other anomalies."},"zh":{"name":"中间指/趾畸形","synonyms":["轴间多指（趾）畸形"]},"tr":{"name":"Merkezi polidaktili","synonyms":["Mezoaksiyel polidaktili"]}},"xrefs":[{"source":"ICD-10","code":"Q69.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LB78.3","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1185710166"},{"source":"ICD-11","code":"LB78.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"243366415"},{"source":"UMLS","code":"C0431903","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[{"type":"Referred to","orpha":295010,"name":"OBSOLETE: Central polydactyly of toes","status":"inactive"},{"type":"Referred to","orpha":295171,"name":"OBSOLETE: Central polydactyly of fingers, unilateral","status":"inactive"},{"type":"Referred to","orpha":295173,"name":"OBSOLETE: Central polydactyly of fingers, bilateral","status":"inactive"},{"type":"Referred to","orpha":295183,"name":"OBSOLETE: Central polydactyly of toes, unilateral","status":"inactive"},{"type":"Referred to","orpha":295185,"name":"OBSOLETE: Central polydactyly of toes, bilateral","status":"inactive"}],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":498470,"name":"Non-syndromic complex polydactyly","classifications":[147,156,199]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}