{"orpha":293462,"name":"Pre-Descemet corneal dystrophy","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["PDCD"],"definition":"Pre-Descemet corneal dystrophy (PDCD) is a rare form of stromal corneal dystrophy characterized by focal, fine, gray opacities in the deep stroma immediately anterior to the Descemet membrane, with no effect on vision.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-293462/","orphanet_url":"https://www.orpha.net/en/disease/detail/293462","names":{"fr":{"name":"Dystrophie cornéenne pré-descemétique","synonyms":["PDCD"],"definition":"La dystrophie cornéenne pré-descemétique (PDCD) est une forme rare de dystrophie cornéenne stromale caractérisée par de fines opacités grises focales sur le stroma profond immédiatement derrière la membrane de Descemet, sans impact sur la vision."},"de":{"name":"Prae-Descemet-Hornhautdystrophie","synonyms":["PDCD"],"definition":"Die Prä-Descemet-Hornhautdystrophie (PDCD) ist eine seltene Form der Stroma-Hornhautdystrophie und gekennzeichnet durch fokale feine graue Trübungen im tiefen Stroma direkt vor der Descemet-Membran, ohne Auswirkungen auf die Sehkraft."},"es":{"name":"Distrofia corneal predescemética","synonyms":["PDCD"],"definition":"La distrofia corneal predescemética (PDCD) es una forma rara de distrofia corneal estromal caracterizada por opacidades focales, finas y de color gris, en el estroma profundo, inmediatamente anterior a la membrana de Descemet, y que no tienen efecto en la visión."},"it":{"name":"Distrofia corneale pre-Descemet","synonyms":["PDCD"],"definition":"La distrofia corneale pre-Descemet (PDCD) è una forma rara di distrofia corneale stromale, caratterizzata da opacità focali sottili e grigiastre nello stroma profondo, immediatamente prima della membrana di Descemet, che non comporta nessuna conseguenza per la vista."},"nl":{"name":"Pre-Descemet-corneadystrofie","synonyms":["PDCD","Pre-Descemet-hoornvliesdystrofie"],"definition":"Pre-Descemet-corneadystrofie (PDCD) is een zeldzame vorm van stromale corneadystrofie gekenmerkt door focale, fijne, grijze opaciteiten in het diepe stroma onmiddellijk voor het Descemetmembraan, zonder effect op het gezichtsvermogen."},"pt":{"name":"Distrofia corneana pré-Descemet","synonyms":["PDCD"]},"pl":{"name":"Dystrofia pre-Descementalna","synonyms":["PDCD"],"definition":"Dystrofia pre-Descementalna (PDCD) jest rzadką postacią stromalnej dystrofii rogówki, charakteryzującej się ogniskowymi, drobnymi, szarymi zmętnieniami w głębokiej stromie, bezpośrednio przed błoną Descemeta, bez wpływu na widzenie"},"cs":{"name":"Dystrofie rohovky před Descemetovou membránou","synonyms":["PDCD"]},"uk":{"name":"Дистрофія рогівки до дегенеративної дистрофії","synonyms":["PDCD"],"definition":"Pre-Descemet corneal dystrophy (PDCD) is a rare form of stromal corneal dystrophy characterized by focal, fine, gray opacities in the deep stroma immediately anterior to the Descemet membrane, with no effect on vision."},"zh":{"name":"后弹力层前角膜营养不良","synonyms":["Descemet前角膜营养不良"],"definition":"德斯密膜前角膜营养不良（PDCD）是一种罕见的角膜基质营养不良，其特征是在紧邻德斯密膜的深层基质中出现局灶性、细小的灰色浑浊，对视力无影响。"},"tr":{"name":"Pre-Descemet korneal distrofi","synonyms":["PDCD"]}},"xrefs":[{"source":"ICD-10","code":"H18.5","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9A70.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"2027634766"},{"source":"MONDO","code":"0017392","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0339282","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":98626,"name":"Stromal corneal dystrophy","classifications":[156,189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Unknown"],"onset":["Adult"],"prevalence":[{"type":"Cases/families","qualification":"Case(s)","class":null,"value":5.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}