{"orpha":279922,"name":"Infectious anterior uveitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare ophthalmic disorder characterized by inflammation primarily of the anterior part of the uvea (iris and ciliary body), due to an infectious etiology. Clinical symptoms are pain, redness, photophobia, and variable visual loss. Signs on examination include presence of inflammatory cells in the anterior chamber and anterior vitreous, keratic precipitates, hypopyon, iris nodules, posterior synechiae, and miosis, among others.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-279922/","orphanet_url":"https://www.orpha.net/en/disease/detail/279922","names":{"fr":{"name":"Uvéite antérieure infectieuse","definition":"Maladie ophtalmique rare caractérisée par une inflammation principalement de la partie antérieure de l'uvée (iris et corps ciliaire), due à une étiologie infectieuse. Les signes cliniques sont la douleur, la rougeur, la photophobie et une baisse de l'acuité visuelle d'intensité variable. Les signes cliniques à l'examen sont, entre autres, la présence de cellules inflammatoires dans la chambre antérieure et le vitré antérieur, des précipités kératiques, un hypopion, des nodules iriens, des synéchies postérieures et un myosis."},"de":{"name":"Uveitis, anteriore, infektiöse Form","definition":"Eine seltene Augenerkrankung, die durch eine Entzündung vor allem des vorderen Teils der Uvea (Iris und Ziliarkörper) gekennzeichnet ist und auf eine infektiöse Ätiologie zurückgeht. Klinische Symptome sind Schmerzen, Rötung, Photophobie und variabler Sehverlust. Zu den Anzeichen bei der Untersuchung gehören u. a. das Vorhandensein von Entzündungszellen in der vorderen Augenkammer und im vorderen Glaskörper, keratische Ausfällungen, Hypopyon, Irisknötchen, hintere Synechien und Miosis."},"es":{"name":"Uveítis anterior infecciosa","definition":"Es un trastorno oftalmológico poco frecuente caracterizado por una inflamación principalmente en la parte anterior de la úvea (el iris y el cuerpo ciliar), debido a una etiología infecciosa. Los síntomas clínicos son dolor, enrojecimiento de los ojos, fotofobia y pérdida visual variable. Los signos de exploración incluyen la presencia de células inflamatorias en la cámara anterior y en el vítreo anterior, precipitados queráticos, hipopión, nódulos en el iris, sinequias posteriores y miosis, entre otros."},"it":{"name":"Uveite anteriore infettiva","definition":"Si tratta di una malattia oculare rara, caratterizzata dall'infiammazione della porzione anteriore dell'uvea (iride e corpo ciliare), secondaria ad un'infezione. I segni clinici sono il dolore, l'arrossamento, la fotofobia e la compromissione di gravità variabile della vista. Sono presenti cellule infiammatorie nella camera anteriore e nel vitreo anteriore, precipitati cheratici, ipopion, noduli dell'iride, sinechie posteriori e miosi."},"nl":{"name":"Infectieuze anterieure uveïtis","definition":"Een zeldzame aandoening van oog, gekarakteriseerd door inflammatie van voornamelijk anterieur deel van uvea (iris en corpus ciliare), als gevolg van een infectieuze etiologie. Klinische symptomen zijn pijn, roodheid, fotofobie, en variabel verlies van gezichtsvermogen. Verschijnselen bij onderzoek zijn onder meer aanwezigheid van inflammatoire cellen in voorste oogkamer en anterieur glasvocht, keratitische precipitaten, hypopyon, noduli van iris, posterieure synechieën, en miose."},"pt":{"name":"Uveíte anterior infeciosa"},"pl":{"name":"Zakaźne zapalenie przedniego odcinka błony naczyniowej oka"},"cs":{"name":"Infekční přední uveitida"},"uk":{"name":"Інфекційний передній увеїт","definition":"A rare ophthalmic disorder characterized by inflammation primarily of the anterior part of the uvea (iris and ciliary body), due to an infectious etiology. Clinical symptoms are pain, redness, photophobia, and variable visual loss. Signs on examination include presence of inflammatory cells in the anterior chamber and anterior vitreous, keratic precipitates, hypopyon, iris nodules, posterior synechiae, and miosis, among others."},"zh":{"name":"感染性前葡萄膜炎"},"tr":{"name":"Enfeksiyöz ön üveit"}},"xrefs":[{"source":"ICD-10","code":"H20.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"H20.1","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"H20.2","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"H20.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"H20.9","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9A96.2","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"404886274"},{"source":"MONDO","code":"0017210","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0154911","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":280886,"name":"Anterior uveitis","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":27.7,"area":"United States","status":"Validated","source":"32841267[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}