{"orpha":279919,"name":"Infectious posterior uveitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare ophthalmic disorder characterized by inflammation of the posterior uveal tract (retina and choroid), due to an infectious etiology. Presenting symptoms are decreased visual acuity, visual field defects, floaters, photopsia, photophobia, and occasionally pain. Signs on examination include conjunctival injection, keratic precipitates, retrolental cells, inflammatory infiltrates on the retina, macular edema, and peripheral retinal neovascularization, among others. Complications (such as cataracts, band keratopathy, glaucoma, cystoid macula edema, and retinal detachment) may lead to permanent vision loss.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-279919/","orphanet_url":"https://www.orpha.net/en/disease/detail/279919","names":{"fr":{"name":"Uvéite postérieure infectieuse","definition":"Maladie ophtalmique rare caractérisée par une inflammation du tractus uvéal postérieur (rétine et choroïde), d'origine infectieuse. Les symptômes observés sont une baisse de l'acuité visuelle, des anomalies du champ visuel, des corps flottants, une photopsie, une photophobie et parfois des douleurs. Les signes cliniques à l'examen sont notamment une injection conjonctivale, des précipités kératiques, des cellules rétrolentales, des infiltrats inflammatoires sur la rétine, un oedème maculaire et une néovascularisation rétinienne périphérique. Les complications (telles que la cataracte, la kératopathie en bandelette, le glaucome, l'oedème maculaire cystoïde et le décollement de la rétine) peuvent causer une perte permanente de vision."},"de":{"name":"Uveitis, posteriore, infektiöse Form","definition":"Eine seltene Augenerkrankung, die durch eine Entzündung der hinteren Aderhaut (Netzhaut und Aderhaut) gekennzeichnet ist und auf eine infektiöse Ätiologie zurückgeht. Die Symptome sind verminderte Sehschärfe, Gesichtsfelddefekte, Floater, Photopsie, Photophobie und gelegentlich Schmerzen. Zu den Anzeichen bei der Untersuchung gehören u. a. konjunktivale Injektionen, keratische Präzipitate, retrolentale Zellen, entzündliche Infiltrate auf der Netzhaut, Makulaödeme und periphere retinale Neovaskularisationen. Komplikationen (wie Katarakt, Bandkeratopathie, Glaukom, zystoides Makulaödem und Netzhautablösung) können zu einem dauerhaften Sehverlust führen."},"es":{"name":"Uveítis posterior infecciosa","definition":"Es un trastorno oftalmológico poco frecuente caracterizado por una inflamación del tracto uveal posterior (la retina y la coroides), debido a una etiología infecciosa. Los síntomas de presentación son disminución de la agudeza visual, defectos del campo visual, miodesopsias, fotopsia, fotofobia y, en ocasiones, dolor. Los signos de exploración incluyen inyección conjuntival, precipitados queráticos, células retrolentales, infiltrados inflamatorios en la retina, edema macular y neovascularización retiniana periférica, entre otros. Las complicaciones (tales como cataratas, queratopatía en banda, glaucoma, edema macular quístico y desprendimiento de retina) pueden derivar en una pérdida permanente de la visión."},"it":{"name":"Uveite posteriore infettiva","definition":"Si tratta di una malattia oculare rara, caratterizzata dall'infiammazione del tratto posteriore dell'uvea (retina e coroide) secondaria ad un'infezione. I segni clinici d'esordio comprendono la riduzione dell'acuità visiva, i difetti del campo visivo, le miodesopsie, le fotopsie, la fotofobia e, occasionalmente, il dolore. Sono presenti iniezione congiuntivale, precipitati cheratici, cellule retrolentali, infiltrati infiammatori sulla retina, edema della macula e neovascolarizzazione retinica periferica. Le complicanze (cataratta, cheratopatia a banda, glaucoma, edema maculare cistoide e distacco della retina) possono causare la cecità permanente."},"nl":{"name":"Infectieuze posterieure uveïtis","definition":"Een zeldzame aandoening van oog, gekarakteriseerd door inflammatie van posterieur deel van uvea (netvlies en vaatvlies), als gevolg van een infectieuze etiologie. Presenterende symptomen zijn verminderde gezichtsscherpte, defecten van visueel veld, glasvochttroebeling, fotopsie, fotofobie, en occasioneel pijn. Verschijnselen bij onderzoek zijn onder meer hyperemie van conjunctiva, keratitische precipitaten, retrolentale cellen, inflammatoire infiltraten in retina, macula-oedeem, en perifere retinale neovascularisatie. Complicaties (zoals cataract, bandkeratopathie, glaucoom, cystoid maculaoedeem, en netvliesloslating) kunnen leiden tot permanent verlies van gezichtsvermogen."},"pt":{"name":"Uveíte posterior infeciosa"},"pl":{"name":"Zakaźne zapalenie tylnego odcinka błony naczyniowej oka"},"cs":{"name":"Infekční zadní uveitida"},"uk":{"name":"Інфекційний задній увеїт","definition":"A rare ophthalmic disorder characterized by inflammation of the posterior uveal tract (retina and choroid), due to an infectious etiology. Presenting symptoms are decreased visual acuity, visual field defects, floaters, photopsia, photophobia, and occasionally pain. Signs on examination include conjunctival injection, keratic precipitates, retrolental cells, inflammatory infiltrates on the retina, macular edema, and peripheral retinal neovascularization, among others. Complications (such as cataracts, band keratopathy, glaucoma, cystoid macula edema, and retinal detachment) may lead to permanent vision loss."},"zh":{"name":"感染性后葡萄膜炎"},"tr":{"name":"Enfeksiyöz posterior üveit"}},"xrefs":[{"source":"ICD-10","code":"H32.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"9B65.1","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1722408748"},{"source":"MONDO","code":"0017209","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5230265","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97966,"name":"Rare ophthalmic disorder"},"parents":[{"orpha":280892,"name":"Posterior uveitis","classifications":[189]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Value and class","class":"1-5 / 10 000","value":23.4,"area":"United States","status":"Validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}