{"orpha":268926,"name":"Midline cerebral malformation","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":["Midline brain malformation"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-268926/","orphanet_url":"https://www.orpha.net/en/disease/detail/268926","names":{"fr":{"name":"Malformation cérébrale médiane"},"de":{"name":"Mittelliniendefekt des Gehirns","synonyms":["Zerebrale Fehlbildung im Bereich der Mittellinie"]},"es":{"name":"Malformación de la linea media cerebral"},"it":{"name":"Malformazione cerebrale della linea mediana"},"nl":{"name":"Middellijn cerebrale malformatie","synonyms":["Middellijn hersenmalformatie"]},"pt":{"name":"Malformação cerebral da linha média","synonyms":["Malformação do cérebro da linha média"]},"pl":{"name":"Malformacje linii pośrodkowej mózgu","synonyms":["Midline brain malformation"]},"cs":{"name":"Středočárové malformace mozku","synonyms":["Středočárová mozková malformace"]},"uk":{"name":"Серединна церебральна мальформація","synonyms":["Серединна вада розвитку головного мозку"]},"zh":{"name":"脑中线畸形","synonyms":["脑中线畸形"]},"tr":{"name":"Orta hat serebral malformasyon","synonyms":["Orta hat beyin malformasyonu"]}},"xrefs":[{"source":"MONDO","code":"17090","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5679771","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":269553,"name":"Genetic cerebral malformation","classifications":[156]},{"orpha":199633,"name":"Non-syndromic cerebral malformation","classifications":[147,181]}],"children":[{"orpha":1126,"name":"Aprosencephaly cerebellar dysgenesis","type":"Malformation syndrome"},{"orpha":566847,"name":"Aprosencephaly/atelencephaly spectrum","type":"Morphological anomaly"},{"orpha":314621,"name":"Duplication of the pituitary gland","type":"Morphological anomaly"},{"orpha":2162,"name":"Holoprosencephaly","type":"Malformation syndrome"},{"orpha":280200,"name":"Microform holoprosencephaly","type":"Malformation syndrome"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}