{"orpha":268357,"name":"Neural tube closure defect","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-268357/","orphanet_url":"https://www.orpha.net/en/disease/detail/268357","names":{"fr":{"name":"Défaut de fermeture du tube neural"},"de":{"name":"Verschlussdefekt des Neuralrohrs"},"es":{"name":"Defectos del cierre del tubo neural"},"it":{"name":"Difetto di chiusura del tubo neurale"},"nl":{"name":"Sluitingsdefect van neurale buis"},"pt":{"name":"Defeito do encerramento do tubo neural"},"pl":{"name":"Defekt zamknięcia cewy nerwowej"},"cs":{"name":"Porucha uzávěru neurální trubice"},"uk":{"name":"Дефект закриття нервової трубки"},"zh":{"name":"神经管闭合缺陷"},"tr":{"name":"Nöral tüp kapanma defekti"}},"xrefs":[{"source":"OMIM","code":"182940","qualifier":"BTNT","icd_relation":null,"validated":true},{"source":"OMIM","code":"301410","qualifier":"BTNT","icd_relation":null,"validated":true},{"source":"OMIM","code":"601634","qualifier":"BTNT","icd_relation":null,"validated":true},{"source":"MONDO","code":"17059","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5680742","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":3388,"name":"Neural tube defect","classifications":[147,156,181]}],"children":[{"orpha":645282,"name":"Anomaly of the filum","type":"Clinical group"},{"orpha":823,"name":"Spina bifida and other spinal dysraphisms","type":"Category"},{"orpha":645276,"name":"Spinal cord lipoma","type":"Clinical group"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}