{"orpha":2583,"name":"Mycetoma","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Madura foot"],"definition":"A neglected tropical infection, rare in Europe, characterized by subcutaneous tumorous lesions in which mycetoma grains containing the causative agent can be observed. Mycetoma is a broad term encompassing both actinomycetoma (bacterial) and eumycetoma (fungal).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-2583/","orphanet_url":"https://www.orpha.net/en/disease/detail/2583","names":{"fr":{"name":"Mycétome","synonyms":["Pied de Madura"],"definition":"Infection tropicale négligée, rare en Europe, caractérisée par des lésions tumorales sous-cutanées dans lesquelles on peut observer des grains de mycétome contenant l'agent causal. Le terme «&nbsp;mycétome&nbsp;» est un terme générique englobant à la fois l'actinomycétome (bactérien) et l'eumycétome (fongique)."},"de":{"name":"Myzetom","synonyms":["Madurafuß","Maduramykose"],"definition":"Eine wenig bekannte tropische Infektion, die in Europa selten vorkommt und durch tumorartige subkutane Läsionen gekennzeichnet ist, in denen erregerhaltige Myzetomkörner beobachtet werden können. Myzetom ist ein Sammelbegriff für Aktinomyzetom (bakteriell) und Eumyetom (pilzlich)."},"es":{"name":"Micetoma","synonyms":["Pie de madura"],"definition":"Es una infección tropical desatendida, poco frecuente en Europa, que se caracteriza por lesiones tumorales subcutáneas en las que se pueden observar gránulos de micetoma que contienen el agente causal. El término micetoma es amplio y abarca tanto el actinomicetoma (bacteriano) como el eumicetoma (fúngico)."},"it":{"name":"Micetoma","synonyms":["Piede di Madura"]},"nl":{"name":"Mycetoom","synonyms":["Madoera-voet","Madura-voet"],"definition":"Een verwaarloosde tropische infectie, zeldzaam in Europa, gekenmerkt door subcutane tumorachtige laesies waarin mycetoom-korrels die de ziekteverwekker bevatten, kunnen waargenomen worden. Mycetoom is een brede term die zowel actinomycetoom (bacterieel) als eumycetoom (fungaal) omvat."},"pt":{"name":"Micetoma"},"pl":{"name":"Grzybica madurska","synonyms":["Stopa madurska"],"definition":"Infekcja tropikalna, rzadka w Europie, charakteryzująca się podskórnymi zmianami guzowatymi, w których obecne są ziarna mycetoma zawierające czynnik sprawczy. Mycetoma to szerokie pojęcie obejmujące zarówno actinomycetoma (pochodzenie bakteryjne), jak i eumycetoma (pochodzenie grzybicze)."},"cs":{"name":"Mycetom","synonyms":["Madurská noha"]},"uk":{"name":"Міцетома","synonyms":["Мадурська нога"],"definition":"Subcutaneous inflammatory pseudotumors containing fungal or actinomycetic (bacteria with branched filaments) granules or grains."},"zh":{"name":"马杜拉分枝菌病","synonyms":["马杜拉足"]},"tr":{"name":"Misetom","synonyms":["Madura ayak"]}},"xrefs":[{"source":"ICD-10","code":"B47.0","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"B47.1","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-10","code":"B47.9","qualifier":"BTNT","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1C43","qualifier":"BTNT","icd_relation":"specific","validated":true,"icd11_uri":"168432503"},{"source":"ICD-11","code":"1F29","qualifier":"BTNT","icd_relation":"specific","validated":true,"icd11_uri":"1866587875"},{"source":"ICD-11","code":"1G60.0","qualifier":"BTNT","icd_relation":"specific","validated":true,"icd11_uri":"111175353"},{"source":"MONDO","code":"0016823","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D008271","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0024449","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"3862","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10028427","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163582,"name":"Rare bacterial infectious disease","classifications":[203]},{"orpha":163591,"name":"Rare mycosis","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":0.09,"area":"Sudan","status":"Validated","source":"24244780[PMID]_ORPHANET"},{"type":"Point prevalence","qualification":"Value and class","class":"1-9 / 100 000","value":0.2,"area":"Mauritania","status":"Validated","source":"24244780[PMID]_ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2019-10-10","source":"29808607[PMID]_26738840[PMID]_28837657[PMID]","terms":[{"hpo":"HP:0003330","label":"Abnormal bone structure","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031288","label":"Cobblestone-like hyperkeratosis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001015","label":"Prominent superficial veins","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0005406","label":"Recurrent bacterial skin infections","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002841","label":"Recurrent fungal infections","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0030053","label":"Stiff skin","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0010219","label":"Structural foot deformity","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001482","label":"Subcutaneous nodule","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0011844","label":"Abnormal appendicular skeleton morphology","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0040072","label":"Abnormal forearm bone morphology","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001155","label":"Abnormality of the hand","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002815","label":"Abnormality of the knee","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100763","label":"Abnormality of the lymphatic system","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025245","label":"Cutaneous cyst","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002754","label":"Osteomyelitis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000939","label":"Osteoporosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0031500","label":"Abdominal mass","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0003312","label":"Abnormal form of the vertebral bodies","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000765","label":"Abnormal thorax morphology","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000152","label":"Abnormality of head or neck","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0000707","label":"Abnormality of the nervous system","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0003418","label":"Back pain","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0012062","label":"Bone cyst","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002661","label":"Painless fractures due to injury","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0010550","label":"Paraplegia","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002756","label":"Pathologic fracture","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0031501","label":"Pelvic mass","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0100809","label":"Scalp tenderness","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002953","label":"Vertebral compression fracture","frequency":"Very rare (<4-1%)","criteria":null}]}}