{"orpha":2566,"name":"Chronic Epstein-Barr virus infection syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["CAEBV syndrome","Chronic EBV infection syndrome"],"definition":"Chronic Epstein-Barr virus infection syndrome is a rare infectious disease characterized by familial, primary, chronic Epstein-Barr virus infection which typically manifests with persistent mononucleosis-like signs and symptoms, in the absence of secondary immunodeficiency.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-2566/","orphanet_url":"https://www.orpha.net/en/disease/detail/2566","names":{"fr":{"name":"Syndrome d'infection chronique au virus Epstein-Barr","synonyms":["Syndrome CAEBV","Syndrome d'infection chronique à EBV"],"definition":"Maladie infectieuse rare caractérisée par une infection familiale, primaire et chronique par le virus d'Epstein-Barr qui se manifeste typiquement par des signes et des symptômes persistants de type mononucléose, en l'absence d'immunodéficience secondaire."},"de":{"name":"Ebstein-Barr-Virusinfektion, chronische","synonyms":["CAEBV-Syndrom","EBV-Infektion, chronische"]},"es":{"name":"Síndrome de infección crónica por el virus de Epstein-Barr","synonyms":["Síndrome CAEBV","Síndrome de infección crónica por EBV"],"definition":"Es una enfermedad infecciosa poco frecuente caracterizada por infección familiar primaria y crónica por el virus de Epstein-Barr que, por lo general, se manifiesta con signos y síntomas persistentes parecidos a la mononucleosis en ausencia de inmunodeficiencia secundaria."},"it":{"name":"Sindrome da infezione cronica da virus di Epstein-Barr","definition":"La sindrome da infezione cronica da virus di Epstein-Barr è una malattia infettiva rara, caratterizzata da un'infezione primaria cronica familiare da virus di Epstein-Barr, che di solito esordisce con segni clinici persistenti che ricordano la mononucleosi, senza immunodeficienza secondaria."},"nl":{"name":"Chronische infectie met Epstein-Barrvirus-syndroom","synonyms":["CAEBV-syndroom","Chronische EBV-infectie-syndroom"],"definition":"Chronische infectie met Epstein-Barrvirus-syndroom is een zeldzame infectueuze ziekte en wordt gekarakteriseerd door familiale, primaire, chronische infectie met Epstein-Barrvirus die zich doorgaans manifesteert met aanhoudende mononucleose-achtige tekenen en symptomen, in afwezigheid van secundaire immuundeficiëntie."},"pt":{"name":"Síndrome de infeção crónica por vírus de Epstein-Barr","synonyms":["Síndrome CAEBV","Síndrome de infeção EBV crónica"]},"pl":{"name":"Zespół przewlekłego zakażenia wirusem Epsteina i Barr","synonyms":["CAEBV syndrome","Chronic EBV infection syndrome"],"definition":"*Zespół przewlekłego zakażenia wirusem Epsteina i Barr jest rzadką chorobą zakaźną, która charakteryzuje się rodzinną, pierwotną, przewlekłą infekcją wywołaną wirusem Epsteina i Barr i która zwykle daje uporczywe objawy przypominające mononukleozę zakaźną, przy braku wtórnego niedoboru odporności."},"cs":{"name":"Chronická EBV infekce","synonyms":["CAEBV syndrom","Syndrom chronické EBV infekce"]},"uk":{"name":"Синдром хронічної вірусної інфекції Епштейна-Барр","synonyms":["Синдром CAEBV","Синдром хронічної EBV-інфекції"],"definition":"Chronic Epstein-Barr virus infection syndrome is a rare infectious disease characterized by familial, primary, chronic Epstein-Barr virus infection which typically manifests with persistent mononucleosis-like signs and symptoms, in the absence of secondary immunodeficiency."},"zh":{"name":"慢性EB病毒感染综合征","synonyms":["慢性EB病毒感染综合征"]},"tr":{"name":"Kronik Epstein-Barr virüs enfeksiyonu sendromu","synonyms":["CAEBV sendromu","Kronik EBV enfeksiyon sendromu"]}},"xrefs":[{"source":"OMIM","code":"226990","qualifier":"E","icd_relation":null,"validated":true},{"source":"ICD-10","code":"B27.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"1D81.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"MONDO","code":"0009194","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4751209","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"9534","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163585,"name":"Rare viral disease","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Unknown"],"onset":["Adolescent","Adult","Childhood"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET_21348109[PMID]"}],"phenotypes":null}