{"orpha":254749,"name":"Tricarboxylic acid cycle disorder","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":["Citric acid cycle disorder","Krebs cycle disorder","TCA cycle disorder"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-254749/","orphanet_url":"https://www.orpha.net/en/disease/detail/254749","names":{"fr":{"name":"Anomalie du cycle des acides tricarboxyliques","synonyms":["Anomalie du cycle de Krebs","Anomalie du cycle de l'acide citrique","Anomalie du cycle des TCA"]},"de":{"name":"Zitronensäurezyklusstörung","synonyms":["Krankheiten des Tricarbonsäurezyklus"]},"es":{"name":"Trastorno del ciclo de los ácidos tricarboxílicos","synonyms":["Trastorno del ciclo de Krebs","Trastorno del ciclo de los TCA","Trastorno del ciclo del ácido cítrico"]},"it":{"name":"Difetto del ciclo degli acidi tricarbossilici","synonyms":["Difetto del ciclo degli TCA","Difetto del ciclo dell'acido citrico","Difetto del ciclo di Krebs"]},"nl":{"name":"Tricarboxylzuurcyclusstoornis","synonyms":["Cirtoenzuurcyclusstoornis","Krebscyclusstoornis","TCA-cyclusstoornis"]},"pt":{"name":"Doença do ciclo do ácido tricarboxílico","synonyms":["Doença do ciclo TCA","Doença do ciclo de Krebs","Doença do ciclo do ácido cítrico"]},"pl":{"name":"Zaburzenia cyklu kwasów trójkarboksylowych","synonyms":["Zaburzenia cyklu Krebsa","Zaburzenia cyklu kwasu cytrynowego","Zaburzenia cyklu TCA"]},"cs":{"name":"Porucha cyklu trikarboxylických kyselin","synonyms":["Porucha citrátového cyklu","Porucha Krebsova cyklu","Porucha TCA cyklu"]},"uk":{"name":"Порушення циклу трикарбонових кислот","synonyms":["Порушення циклу лимонної кислоти","Порушення циклу Кребса","Порушення циклу ТСА"]},"zh":{"name":"三羧酸循环障碍","synonyms":["柠檬酸循环障碍"]},"tr":{"name":"Trikarboksilik asit döngüsü bozukluğu","synonyms":["TCA döngüsü bozukluğu","Krebs döngüsü bozukluğu","Sitrik asit döngüsü bozukluğu"]}},"xrefs":[{"source":"MONDO","code":"0016790","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"16790","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5679646","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68367,"name":"Rare inborn error of metabolism"},"parents":[{"orpha":79200,"name":"Disorder of energy metabolism","classifications":[150,156]}],"children":[{"orpha":615964,"name":"Acute reversible leukoencephalopathy with increased urinary alpha-ketoglutarate","type":"Disease"},{"orpha":24,"name":"Fumaric aciduria","type":"Disease"},{"orpha":313850,"name":"Infantile cerebellar-retinal degeneration","type":"Disease"},{"orpha":31,"name":"Oxoglutaric aciduria","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}