{"orpha":251902,"name":"Atypical papilloma of choroid plexus","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Atypical CPP","Atypical choroid plexus papilloma"],"definition":"A very rare type of choroid plexus tumor that, contrary to papilloma of the choroid plexus, has an increased likelihood of progression to carcinoma and of recurrence. It displays brisk mitoses, nuclear pleomorphism, raised cellular density, obscurity of the papillary growth pattern, and cell necrosis.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-251902/","orphanet_url":"https://www.orpha.net/en/disease/detail/251902","names":{"fr":{"name":"Papillome atypique des plexus choroïdes","synonyms":["CPP atypique"],"definition":"Le papillome atypique des plexus choroïdes est un type très rare de tumeur des plexus choroïdes qui, contrairement au papillome des plexus choroïdes, a une tendance accrue à progresser vers un carcinome et à récidiver. Il se manifeste par des mitoses brusques, un plémorphisme nucléaire, une augmentation de la densité cellulaire, un schéma de croissance papillaire obscur et une nécrose cellulaire."},"de":{"name":"Choroidplexuspapillom, atypisches","synonyms":["CPP, atypisches"]},"es":{"name":"Papiloma atípico del plexo coroideo","synonyms":["PPC atípico","Papiloma del plexo coroideo atípico"],"definition":"Es un tipo muy poco frecuente de tumor del plexo coroideo que, al contrario del papiloma de plexo coroideo, tiene una mayor probabilidad de progresión a carcinoma y de recurrencia. Presenta una tasa mitótica elevada, pleomorfismo nuclear, densidad celular elevada, ensombrecimiento del patrón de crecimiento papilar, y necrosis celular."},"it":{"name":"Papilloma atipico del plesso corioideo","definition":"Il papilloma atipico del plesso corioideo è una forma molto rara di tumore del plesso corioideo (si veda questo termine). A differenza del papilloma del plesso corioideo (si veda questo termine), ha maggiore rischio di evolvere in carcinoma e di recidivare. È caratterizzato da attività mitotica vivace, pleomorfismo nucleare, aumento della densità cellulare, necrosi cellulare, mentre non è nota la tipologia della crescita papillare."},"nl":{"name":"Atypisch papilloom van plexus choroideus","synonyms":["Atypisch plexus choroideus-papilloom","Atypisch CPP"],"definition":"Een zeer zeldzaam type van plexus choroideus-tumor dat, in tegenstelling tot papilloom van plexus choroideus, een verhoogde waarschijnlijkheid heeft om te evolueren naar carcinoom en op recidief. Het vertoont snelle mitosen, nucleair pleomorfisme, verhoogde cellulaire dichtheid, onduidelijkheid van het knobbelachtig groeipatroon, en necrose van cellen."},"pt":{"name":"Papiloma atípico do plexo coróide"},"pl":{"name":"Atypowy brodawczak splotu naczyniówkowego","synonyms":["Atypical CPP","Atypical choroid plexus papilloma"]},"cs":{"name":"Atypický papilom choroidálního plexu","synonyms":["Atypical CPP","Atypical choroid plexus papilloma"]},"uk":{"name":"Атипова папілома судинного сплетіння","synonyms":["Атипова папілома судинного сплетіння","Атиповий CPP"],"definition":"A very rare type of choroid plexus tumor that, contrary to papilloma of the choroid plexus, has an increased likelihood of progression to carcinoma and of recurrence. It displays brisk mitoses, nuclear pleomorphism, raised cellular density, obscurity of the papillary growth pattern, and cell necrosis."},"zh":{"name":"非典型乳头状脉络丛瘤","synonyms":["非典型乳头状脉络丛瘤"],"definition":"一种非常罕见的脉络丛肿瘤，与脉络丛乳头状瘤相反，它有更高的癌变和复发的可能性。表现为有丝分裂活跃，核多形性，细胞密度增高，乳头状生长方式模糊，细胞坏死。"},"tr":{"name":"Koroid pleksusun atipik papilloması","synonyms":["Atipik CPP","Atipik koroid pleksus papillom"]}},"xrefs":[{"source":"ICD-10","code":"D33.1","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2A00.22","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1903052817"},{"source":"MONDO","code":"0002684","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1266176","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":251896,"name":"Choroid plexus tumor","classifications":[181,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}