{"orpha":251867,"name":"Classic medulloblastoma","type":"Histopathological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":"Classic medulloblastoma is a histological variant of medulloblastoma ,an embryonic malignancy, having a midline location, occurring most often in children and manifesting with variable symptoms such as headaches, nausea, vomiting and ataxia.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-251867/","orphanet_url":"https://www.orpha.net/en/disease/detail/251867","names":{"fr":{"name":"Médulloblastome classique","definition":"Le médulloblastome classique est un variant histologique du médulloblastome, une malignité embryonnaire avec une location médiane. Il survient le plus souvent chez l'enfant et se manifeste par des signes variés tels que des céphalées, des nausées, des vomissements et une ataxie."},"de":{"name":"Medulloblastom, klassisches"},"es":{"name":"Meduloblastoma clásico","definition":"El meduloblastoma clásico es una variante histológica del meduloblastoma (consulte este término), una neoplasia embrionaria. Se localiza en la línea media, se da con mayor frecuencia en niños y se manifiesta con síntomas variables como dolores de cabeza, náuseas, vómitos y ataxia."},"it":{"name":"Medulloblastoma classico","definition":"Il medulloblastoma classico è una variante istologica del medulloblastoma (si veda questo termine), un tumore embrionale maligno, che si localizza nella linea mediana e interessa di solito i bambini, con sintomi variabili come le cefalee, la nausea, il vomito e l'atassia."},"nl":{"name":"Klassiek medulloblastoom","definition":"Klassiek medulloblastoom is een histologische variant van de embryonale aandoening medulloblastoom (zie deze term) die is gesitueerd op de middenlijn, het vaakst voorkomt in kinderen, en zich manifesteert met variabele symptomen zoals hoofdpijn, misselijkheid, braken en ataxie."},"pt":{"name":"Meduloblastoma clássico"},"pl":{"name":"Rdzeniak zarodkowy klasyczny"},"cs":{"name":"Klasický meduloblastom"},"uk":{"name":"Класична медулобластома","definition":"Classic medulloblastoma is a histological variant of medulloblastoma (see this term) ,an embryonic malignancy, having a midline location, occurring most often in children and manifesting with variable symptoms such as headaches, nausea, vomiting and ataxia."},"zh":{"name":"典型成神经管细胞瘤","definition":"经典髓母细胞瘤是髓母细胞瘤(见该词条)的组织学变异型，髓母细胞瘤是一种胚胎恶性肿瘤，位于中线，最常发生在儿童，表现为各种症状，如头痛、恶心、呕吐和共济失调。"},"tr":{"name":"Klasik medulloblastom"}},"xrefs":[{"source":"OMIM","code":"155255","qualifier":"NTBT","icd_relation":null,"validated":true},{"source":"ICD-10","code":"C71.6","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2A00.10","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1548011794"},{"source":"ICD-11","code":"XH0RY1","qualifier":"BTNT","icd_relation":"specific","validated":true,"icd11_uri":"913133221"},{"source":"ICD-11","code":"XH3EX1","qualifier":"BTNT","icd_relation":"specific","validated":true,"icd11_uri":"552492151"},{"source":"MONDO","code":"0016712","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C1707400","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":616,"name":"Medulloblastoma","classifications":[181,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Childhood"],"prevalence":[],"phenotypes":null}