{"orpha":251646,"name":"Anaplastic ependymoma","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare, malignant type of ependymoma that most often arises in the supratentorial region of the brain of children and young adults and that manifests with variable symptoms including headaches, nausea, vision impairment, memory loss and difficulty walking.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-251646/","orphanet_url":"https://www.orpha.net/en/disease/detail/251646","names":{"fr":{"name":"Ependymome anaplasique","definition":"L'épendymome anaplasique est un type d'épendydome malin et rare qui survient le plus souvent dans la région supratentorielle du cerveau de l'enfant et du jeune adulte. Il se manifeste par des signes variables incluant des céphalées, des nausées, des troubles de la vision, une perte de mémoire et des troubles de la marche."},"de":{"name":"Ependymom, anaplastisches","definition":"Ein seltener maligner Typ des Ependymoms, der am häufigsten in der supratentoriellen Region des Gehirns von Kindern und jungen Erwachsenen entsteht und sich mit unterschiedlichen Symptomen wie Kopfschmerzen, Übelkeit, Sehstörungen, Gedächtnisverlust und Gehbehinderung äußert."},"es":{"name":"Ependimoma anaplásico","definition":"Es un tipo de ependimoma maligno poco frecuente que aparece más a menudo en la región supratentorial del cerebro en niños y adultos jóvenes. Se manifiesta con síntomas variables que incluyen dolores de cabeza, náuseas, deficiencia visual, pérdida de memoria y dificultad ambulatoria."},"it":{"name":"Ependimoma anaplastico","synonyms":["Ependimoma di alto grado"],"definition":"L'ependimoma anaplastico è una forma rara e maligna di ependimoma (si veda questa termine), che origina spesso nella regione sovratentoriale del cervello dei bambini e dei giovani adulti. Si presenta con sintomi variabili come le cefalee, la nausea, il deficit visivo, la perdita della memoria e le difficoltà nella deambulazione."},"nl":{"name":"Anaplastisch ependymoom","definition":"Een zeldzaam, kwaadaardig type van ependymoom dat meestal ontstaat in de supratentoriële regio van de hersenen van kinderen en jonge volwassenen en zich manifesteert met variabele symptomen waaronder hoofdpijn, misselijkheid, verlies van gezichtsvermogen, geheugenverlies en moeite om te stappen."},"pt":{"name":"Ependimona anaplásico","synonyms":["Ependimona de alto grau"]},"pl":{"name":"Wyściółczak anaplastyczny","synonyms":["Wyściółczak o wysokim stopniu złośliwości"]},"cs":{"name":"Anaplastický ependymom","synonyms":["High-grade ependymom"]},"uk":{"name":"Анапластична епендимома","definition":"A rare, malignant type of ependymoma that most often arises in the supratentorial region of the brain of children and young adults and that manifests with variable symptoms including headaches, nausea, vision impairment, memory loss and difficulty walking."},"zh":{"name":"间变性室管膜瘤","definition":"一种罕见的恶性室管膜瘤，最常发生在儿童和年轻人的大脑幕上区域，表现为各种症状，包括头痛、恶心、视力障碍、记忆力丧失和行走困难。"},"tr":{"name":"Anaplastik ependimom"}},"xrefs":[{"source":"ICD-10","code":"C71.9","qualifier":"NTBT","icd_relation":"index","validated":true},{"source":"ICD-11","code":"2A00.0Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"110266733"},{"source":"ICD-11","code":"XH6922","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"513798842"},{"source":"MONDO","code":"0016700","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0280788","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"10634","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10014968","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":301,"name":"Ependymal tumor","classifications":[181,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adolescent","Adult","Childhood"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.04,"area":"United States","status":"Validated","source":"23660944[PMID]"}],"phenotypes":null}