{"orpha":251639,"name":"Subependymoma","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Subependymoma is a rare and slow growing type of ependymoma, often presenting in middle-aged adults, found more commonly in men than in women, usually located in the fourth and lateral ventricles and manifesting with variable symptoms including headache, nausea, and loss of balance. In some cases it can be asymptomatic. It is usually associated with a better prognosis than other forms of ependymoma.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-251639/","orphanet_url":"https://www.orpha.net/en/disease/detail/251639","names":{"fr":{"name":"Sous-épendymome","synonyms":["Subépendymome"],"definition":"Le sous-épendymome est un type d'épendymome rare et lentement progressif, se présentant souvent chez l'adulte d'âge moyen et observé plus fréquemment chez les hommes que chez les femmes. Il est habituellement situé dans le quatrième ventricule et les ventricules latéraux, et se manifeste par des signes variables incluant des céphalées, des nausées et une perte de l'équilibre. Il peut être asymptomatique dans certains cas. Son pronostic est généralement meilleur que celui des autres formes d'épendymome."},"de":{"name":"Subependymom","definition":"Das Subependymom ist eine seltene und langsam wachsende Form des Ependymoms, die häufig bei Erwachsenen mittleren Alters auftritt, häufiger bei Männern als bei Frauen vorkommt, in der Regel im vierten und seitlichen Ventrikel lokalisiert ist und mit unterschiedlichen Symptomen wie Kopfschmerzen, Übelkeit und Gleichgewichtsstörungen einhergeht. In einigen Fällen kann sie asymptomatisch sein. Es ist in der Regel mit einer besseren Prognose verbunden als andere Formen von Ependymomen."},"es":{"name":"Subependimoma","definition":"El subependimoma es un tipo poco frecuente y de crecimiento lento de ependimoma (consulte este término), que se presenta a menudo en adultos de mediana edad, más frecuente en varones que en mujeres. Suele estar localizado en en cuarto ventrículo y en los ventrículos laterales. Se manifiesta con síntomas variables que incluyen dolor de cabeza, náuseas y pérdida de equilibrio. En algunos casos puede ser asintomático. Suele estar asociado con un diagnóstico más favorable que el de otras formas de ependimoma."},"it":{"name":"Subependimoma","definition":"Il subependimoma è una forma rara, a progressione lenta, di ependimoma (si veda questo termine), che interessa spesso gli adulti di mezza età (più spesso gli uomini che le donne). Di solito, si localizza nel quarto ventricolo e nei ventricoli laterali e si manifesta con sintomi variabili come la cefalea, la nausea e la perdita dell'equilibrio. In alcuni casi, può essere asintomatico. A differenza delle altre forme di ependimoma, di solito, comporta una prognosi migliore."},"nl":{"name":"Subependymoom","definition":"Subependymoom is een zeldzaam en traag groeiend type ependymoom (zie deze term), dat vaak voorkomt in volwassenen van middelbare leeftijd en meer wordt aangetroffen bij mannen dan bij vrouwen. Meestal situeert het zich in de vierde en laterale ventrikels en komt het tot uiting met variabele symptomen waaronder hoofdpijn, misselijkheid, en evenwichtsverlies. In sommige gevallen kan het asymptomatisch zijn. Het is doorgaans geassocieerd met een betere prognose dan andere vormen van ependymoom."},"pt":{"name":"Subependimona"},"pl":{"name":"Podwyściółczak"},"cs":{"name":"Subependymom"},"uk":{"name":"Субепендимома","definition":"Subependymoma is a rare and slow growing type of ependymoma (see this term), often presenting in middle-aged adults, found more commonly in men than in women, usually located in the fourth and lateral ventricles and manifesting with variable symptoms including headache, nausea, and loss of balance. In some cases it can be asymptomatic. It is usually associated with a better prognosis than other forms of ependymoma."},"zh":{"name":"室管膜下瘤","definition":"室管膜下瘤是一种罕见且生长缓慢的室管膜瘤（见该词条），常见于中年人，男性多于女性，通常位于第四脑室和侧脑室，表现为各种症状，包括头痛、恶心和失去平衡。在某些情况下，它可能是无症状的。它通常比其他形式的室管膜瘤预后更好。"},"tr":{"name":"Subepandimom"}},"xrefs":[{"source":"ICD-10","code":"D43.2","qualifier":"NTBT","icd_relation":"index","validated":true},{"source":"ICD-11","code":"2A00.0Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"737144375"},{"source":"ICD-11","code":"2A00.5","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"532013146"},{"source":"ICD-11","code":"XH8FZ9","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1580118719"},{"source":"MONDO","code":"0007667","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D018315","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0206725","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"10070","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":301,"name":"Ependymal tumor","classifications":[181,202]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2019-02-19","source":"29054328[PMID]_29309981[PMID]_30102193[PMID]_24615997[PMID]_25957762[PMID]_28895660[PMID]","terms":[{"hpo":"HP:0002888","label":"Ependymoma","frequency":"Obligate (100%)","criteria":"Diagnostic criterion"},{"hpo":"HP:0025461","label":"Abnormal cell morphology","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002076","label":"Migraine","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012531","label":"Pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002460","label":"Distal muscle weakness","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012534","label":"Dysesthesia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001288","label":"Gait disturbance","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001250","label":"Seizure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0010302","label":"Spinal cord tumor","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030693","label":"Supratentorial neoplasm","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002013","label":"Vomiting","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100013","label":"Neoplasm of the breast","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0002896","label":"Neoplasm of the liver","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0100526","label":"Neoplasm of the lung","frequency":"Very rare (<4-1%)","criteria":null},{"hpo":"HP:0100615","label":"Ovarian neoplasm","frequency":"Very rare (<4-1%)","criteria":null}]}}