{"orpha":251579,"name":"Giant cell glioblastoma","type":"Histopathological subtype","group":"Subtype of disorder","status":"active","flags":[],"synonyms":[],"definition":null,"note":"This disease is described under Glioblastoma","url":"https://raremap.alftech.space/d/ORPHA-251579/","orphanet_url":"https://www.orpha.net/en/disease/detail/251579","names":{"fr":{"name":"Glioblastome à cellules géantes"},"de":{"name":"Riesenzell-Glioblastom"},"es":{"name":"Glioblastoma de células gigantes"},"it":{"name":"Gliobastoma a cellule giganti"},"nl":{"name":"Reuscelglioblastoom"},"pt":{"name":"Glioblastoma de células gigantes"},"pl":{"name":"Glejak wielopostaciowy olbrzymiokomórkowy"},"cs":{"name":"Obrovskobuněčný glioblastom"},"uk":{"name":"Гігантоклітинна гліобластома"},"zh":{"name":"巨细胞胶质母细胞瘤"},"tr":{"name":"Dev hücreli glioblastoma"}},"xrefs":[{"source":"ICD-10","code":"C71.9","qualifier":"NTBT","icd_relation":"index","validated":true},{"source":"ICD-11","code":"2A00.00","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"565094124"},{"source":"ICD-11","code":"XH8UC5","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"221360525"},{"source":"MONDO","code":"0016682","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0334588","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":360,"name":"Glioblastoma","classifications":[181,202]}],"children":[],"genes":[{"symbol":"IDH1","name":"isocitrate dehydrogenase (NADP(+)) 1","gene_type":"gene with protein product","association":"Biomarker tested 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