{"orpha":247165,"name":"Infantile mercury poisoning","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Erythroedema polyneuritis","Feer disease","Infantile acrodynia","Infantile mercury intoxication","Pink disease","Swift disease","Swift-Feer disease"],"definition":"Infantile mercury poisoning is a rare intoxication affecting children, most commonly characterized by erythema of the hands, feet and nose, edematous, painful, pink to red, desquamating fingers and toes, bluish, cold and wet extremities, excessive sweating, irritability, photophobia, muscle weakness, diffuse hypotonia, paresthesia, hypertension and tachycardia, due to elemental, organic or inorganic mercury exposure. Additional manifestations include alopecia, loss of appetite, excessive salivation with red and swollen gums, tooth and nail loss and insomnia.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-247165/","orphanet_url":"https://www.orpha.net/en/disease/detail/247165","names":{"fr":{"name":"Intoxication infantile au mercure","synonyms":["Acrodynie infantile","Empoisonnement infantile au mercure","Erythroedème épidémique","Hydrargyrie infantile","Hydrargyrisme infantile","Maladie de Feer","Maladie de Swift","Maladie de Swift-Feer","Maladie rose","Polynévrite érythroedème"],"definition":"L'intoxication infantile au mercure est une intoxication rare affectant les enfants. Elle se caractérise le plus souvent par un érythème des mains, des pieds et du nez, une desquamation oedémateuse douloureuse des doigts et des orteils, de coloration rose à rouge, des extrémités bleutées, froides et humides, une hyperhidrose, une irritabilité, une photophobie, une faiblesse musculaire, une hypotonie diffuse, une paresthésie, une hypertension et une tachycardie. Elle est due à l'exposition au mercure élémentaire, organique ou inorganique. Les signes additionnels incluent une alopécie, une perte d'appétit, une salivation excessive avec des gencives rouges et gonflées, une perte dentaire et unguéale, et une insomnie."},"de":{"name":"Quecksilbervergiftung, infantile","synonyms":["Feer-Krankheit","Infantile Akrodynie","Infantile Quecksilber-intoxifikation","Pink-Krankheit","Swift-Feer-Krankheit","Swift-Krankheit"],"definition":"Die infantile Quecksilbervergiftung ist eine seltene Vergiftung bei Kindern, die am häufigsten durch Erytheme an Händen, Füßen und Nase, ödematöse, schmerzhafte, rosafarbene bis rote, abschuppende Finger und Zehen, bläuliche, kalte und feuchte Extremitäten, übermäßiges Schwitzen, Reizbarkeit, Photophobie, Muskelschwäche, diffuse Hypotonie, Parästhesie, Hypertonie und Tachykardie aufgrund einer elementaren, organischen oder anorganischen Quecksilberexposition gekennzeichnet ist. Weitere Erscheinungsformen sind Alopezie, Appetitlosigkeit, übermäßiger Speichelfluss mit rotem und geschwollenem Zahnfleisch, Zahn- und Nagelverlust und Schlaflosigkeit."},"es":{"name":"Intoxicación infantil por mercurio","synonyms":["Acrodinia infantil","Enfermedad de Feer","Enfermedad de Pink","Enfermedad de Swift","Enfermedad de Swift-Feer","Envenenamiento infantil por mercurio"],"definition":"La intoxicación infantil por mercurio es una intoxicación poco frecuente. Se origina por la exposición a mercurio elemental, orgánico o inorgánico. Habitualmente cursa con eritema en las manos, pies y nariz, hinchazón o edema en dedos de manos y pies, con dolor, enrojecimiento y descamación, las extremidades muestran un aspecto cianótico (azulado) y están frías y húmedas, la sudoración es excesiva y suele haber irritabilidad, fotofobia, debilidad muscular, hipotonía difusa, parestesia, hipertensión y taquicardia. Otras manifestaciones incluyen alopecia, pérdida de apetito, salivación excesiva con encías rojas e inflamadas, pérdida de dientes y uñas e insomnio."},"it":{"name":"Avvelenamento infantile da mercurio","synonyms":["Acrodinia infantile","Eritroedema polineuritico","Intossicazione infantile da mercurio","Malattia di Feer","Malattia di Pink","Malattia di Swift","Malattia di Swift-Feer"],"definition":"L'avvelenamento infantile da mercurio è un'intossicazione rara che colpisce i bambini. Di solito è caratterizzata da eritema localizzato sulle mani, sui piedi e sul naso; la cute delle dita delle mani e dei piedi è edematosa, dolorante, desquamata, di colore variabile tra il rosa e il rosso; le estremità sono bluastre, fredde e bagnate. Si associano iperidrosi, irritabilità, fotofobia, debolezza muscolare, ipotonia diffusa, parestesia, ipertensione e tachicardia, secondarie all'esposizione al mercurio allo stato elementare, organico o inorganico. Altri segni sono l'alopecia, la perdita dell'appetito, la salivazione eccessiva con gengive rosse e gonfie, la perdita dei denti e delle unghie e l'insonnia."},"nl":{"name":"Infantiele kwikvergiftiging","synonyms":["Pink disease","Ziekte van Feer","Ziekte van Swift","Ziekte van Swift-Feer","Erytroedema polyneuritis","Infantiele acrodynie","Infantiele kwikintoxicatie"],"definition":"Infantiele kwikvergiftiging is een zeldzame vergiftiging die kinderen treft en doorgaans gekarakteriseerd wordt door erytheem van de handen, voeten en neus, oedemateuze, pijnlijke, roze tot rode, afschilferende vingers en tenen, blauwachtige, koude en natte extremiteiten, overmatig zweten, prikkelbaarheid, fotofobie, spierzwakte, diffuse hypotonie, paresthesie, hypertensie en tachycardie, ten gevolge van blootstelling aan elementair, organisch of anorganisch kwik. Bijkomende symptomen zijn alopecie, verlies van eetlust, overmatige speekselafscheiding met rood en gezwollen tandvlees, verlies van tanden en nagels, en insomnia."},"pt":{"name":"Envenenamento da infância por mercúrio"},"pl":{"name":"Zatrucie rtęcią u dzieci","synonyms":["Choroba Feera","Choroba Pinka","Choroba Swifta","Choroba Swifta i Feera","Dziecięca akrodynia","Infantile mercury intoxication","Obrzęk z zaczerwienieniem z powodu zapalenia wielonerwowego"]},"cs":{"name":"Infantilní otrava rtutí","synonyms":["Erythroedema polyneuropathia","Feerova nemoc","Infantilní akrodynie","Infantilní intoxikace rtutí","Swiftova nemoc","Swiftova-Feerova nemoc","Růžová nemoc","Swift-Feerova nemoc"]},"uk":{"name":"Інфантильне отруєння ртуттю","synonyms":["Еритреїдальний поліневрит","Хвороба Фейера","Інфантильна акродинія","Дитяча ртутна інтоксикація","Рожева хвороба","Хвороба Свіфта","Хвороба Свіфта-Фейера"],"definition":"Infantile mercury poisoning is a rare intoxication affecting children, most commonly characterized by erythema of the hands, feet and nose, edematous, painful, pink to red, desquamating fingers and toes, bluish, cold and wet extremities, excessive sweating, irritability, photophobia, muscle weakness, diffuse hypotonia, paresthesia, hypertension and tachycardia, due to elemental, organic or inorganic mercury exposure. Additional manifestations include alopecia, loss of appetite, excessive salivation with red and swollen gums, tooth and nail loss and insomnia."},"zh":{"name":"小儿铅中毒","synonyms":["小儿贡中毒"],"definition":"婴儿汞中毒是一种罕见的儿童中毒，最常见的症状是手、脚、鼻出现红斑，水肿，疼痛，粉红至红色的手指和脚趾脱皮，发蓝、寒冷和潮湿的四肢，大量出汗，易激惹，畏光，肌肉无力，弥漫性肌张力低下，感觉异常，因接触元素、有机或无机汞而引起的高血压和心动过速。其他表现包括脱发，食欲不振，唾液过多，牙龈红肿，牙齿和指甲脱落，失眠。"},"tr":{"name":"İnfantil cıva zehirlenmesi","synonyms":["Feer hastalığı","Pembe hastalık","Swift hastalığı","Swift-Feer hastalığı","İnfantil akrodinya","Eritroödem polinürit","İnfantil cıva zehirlenmesi"]}},"xrefs":[{"source":"ICD-10","code":"T56.1","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"NE61","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1880611519"},{"source":"MONDO","code":"0016588","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4553710","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":108999,"name":"Rare disorder due to toxic effects"},"parents":[{"orpha":556508,"name":"Rare disorder due to poisoning","classifications":[204]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Infancy"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":null}