{"orpha":238305,"name":"Infundibulo-neurohypophysitis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A type of primary hypophysitis characterized by an inflammation of the posterior pituitary and the stalk. The major clinical manifestation is diabetes insipidus with polyuria and polydipsia. Less frequent symptoms are headaches, adrenal insufficiency, hyperprolactinemia and hypogonadism.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-238305/","orphanet_url":"https://www.orpha.net/en/disease/detail/238305","names":{"fr":{"name":"Neurohypophysite infundibulaire","definition":"Insuffisance hypophysaire acquise rare à type d'hypophysite primaire caractérisée par une inflammation de l'hypophyse postérieure et du pédoncule. La principale manifestation clinique est un diabète insipide avec polyurie et polydipsie. Les symptômes moins fréquents sont des maux de tête, une insuffisance surrénale, une hyperprolactinémie et un hypogonadisme."},"de":{"name":"Infundibuloneurohypophysitis"},"es":{"name":"Infundibulo-neurohipofisitis","definition":"La infundibulo-neurohipofisitis es una deficiencia de hormona pituitaria adquirida y poco frecuente, un tipo de hipofisitis primaria caracterizada por inflamación de la hipófisis posterior y el tallo hipofisario. La principal manifestación clínica es la diabetes insípida con poliuria y polidipsia. Son síntomas menos frecuentes la cefalea, insuficiencia suprarrenal, hiperprolactinemia e hipogonadismo."},"it":{"name":"Neuroipofisite infundibulare","definition":"La neuroipofisite infundibulare è un difetto raro acquisito degli ormoni dell'ipofisi, un'ipofisite primitiva caratterizzata dall'infiammazione dell'ipofisi posteriore e dei peduncoli. Il segno clinico principale è il diabete insipido associato a poliuria e polidipsia. Sintomi meno comuni sono la cefalea, l'insufficienza surrenalica, l'iperprolattinemia e l'ipogonadismo."},"nl":{"name":"Infundibulo-neurohypofysitis","definition":"Infundibulo-neurohypofysitis is een zeldzame, verworven hypofysaire hormoondeficiëntie en een type van primaire hypofysitis, gekarakteriseerd door inflammatie van de posterieure hypofyse en de hypofysesteel. De voornaamste klinische manifestatie is diabetes insipidus met polyurie en polydipsie. Minder vaak voorkomende symptomen zijn hoofdpijn, bijnierschorsinsufficiëntie, hyperprolactinemie en hypogonadisme."},"pt":{"name":"Infundibulo-neuro-hipofisite"},"pl":{"name":"Zapalenie części nerwowej i szypuły przysadki","definition":"*Zapalenie części nerwowej i szypuły przysadki jest rzadkim, nabytym niedoborem hormonów przysadki, rodzajem pierwotnego zapalenia przysadki, które charakteryzuje się zapaleniem tylnej części przysadki i szypuły. Głównym objawem klinicznym jest moczówka prosta z wielomoczem i polidypsją. Rzadziej występują bóle głowy, niedoczynność kory nadnerczy, hiperprolaktynemia i hipogonadyzm."},"cs":{"name":"Autoimunitní hypofyzitida"},"uk":{"name":"Інфундибуло-нейрогіпофізит","definition":"A type of primary hypophysitis characterized by an inflammation of the posterior pituitary and the stalk. The major clinical manifestation is diabetes insipidus with polyuria and polydipsia. Less frequent symptoms are headaches, adrenal insufficiency, hyperprolactinemia and hypogonadism."},"zh":{"name":"漏斗神经下垂体炎","definition":"漏斗神经垂体炎是一种罕见的获得性垂体激素缺乏症，是一种以垂体后叶和垂体柄炎症为特征的原发性垂体炎。主要临床表现为尿崩症伴多尿多饮。较少见的症状包括头痛、肾上腺功能不全、高催乳素血症和性腺机能减退。"},"tr":{"name":"Infundibulo-nörohipofizit"}},"xrefs":[{"source":"ICD-10","code":"E23.6","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"5A61.5","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"97299603"},{"source":"MONDO","code":"0016534","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5190834","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97978,"name":"Rare endocrine disease"},"parents":[{"orpha":95506,"name":"Primary hypophysitis","classifications":[193]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}