{"orpha":2372,"name":"Laryngocele","type":"Malformation syndrome","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare congenital laryngeal anomaly characterized by an abnormal dilation of the laryngeal saccule that is filled with air, maintains communication with the laryngeal lumen, and is either confined to the false vocal fold or extends upward, protruding through the thyrohyoid membrane to the neck. Symptoms may include cough, hoarseness, stridor, sore throat and uni- or bilateral swelling of the neck. Blockage of the laryngocele neck can result isn laryngomucocele, and forms laryngopyocele when infected.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-2372/","orphanet_url":"https://www.orpha.net/en/disease/detail/2372","names":{"fr":{"name":"Laryngocèle","definition":"Anomalie congénitale rare du larynx caractérisée par une dilatation anormale du saccule laryngé qui est rempli d'air, à l'origine d'une communication avec la lumière laryngée. Elle est soit confinée au faux pli vocal, soit s'étend vers le haut, faisant saillie à travers la membrane thyrohyoïde jusqu'au cou. Les signes cliniques peuvent inclure une toux, un enrouement, un stridor, un mal de gorge et un gonflement unilatéral ou bilatéral du cou. L'obstruction du col du laryngocèle peut entraîner un laryngomucocèle et, en cas d'infection, un laryngopyocèle."},"de":{"name":"Laryngozele","definition":"Eine seltene angeborene Kehlkopfanomalie, die durch eine abnorme Erweiterung des Kehlkopfsackes gekennzeichnet ist, der mit Luft gefüllt ist, mit dem Kehlkopflumen in Verbindung steht und entweder auf die falsche Stimmlippe beschränkt ist oder sich nach oben erstreckt und durch die Thyreoidea bis zum Hals vorsteht. Zu den Symptomen gehören Husten, Heiserkeit, Stridor, Halsschmerzen und ein- oder beidseitige Schwellungen des Halses. Eine Verstopfung des Laryngocele-Halses kann zu einer Laryngomucocele führen und bildet bei Infektion eine Laryngopyocele."},"es":{"name":"Laringocele","definition":"Es una anomalía laríngea congénita poco frecuente caracterizada por una dilatación anómala llena de aire del sáculo laríngeo, manteniendo la comunicación con la luz laríngea. Se localiza en el pliegue vocal falso o se extiende hacia arriba, sobresaliendo a través de la membrana tirohioidea hasta el cuello. Los síntomas pueden incluir tos, ronquera, estridor, dolor de garganta e inflamación uni- o bilateral del cuello. La obstrucción del cuello del laringocele puede resultar en laringo-mucocele, progresando a laringopiocele cuando se infecta."},"it":{"name":"Laringocele","definition":"Si tratta di un'anomalia congenita rara della laringe, caratterizzata da una dilatazione anomala del sacculo laringeo contenente aria, che comunica con il lume della laringe. L'anomalia può essere limitata alla falsa corda vocale oppure estendersi verso l'alto, sporgendo dalla membrana tiroidea verso il collo. I sintomi comprendono la tosse, la raucedine, lo stridore, il mal di gola e il gonfiore mono- o bilaterale del collo. L'ostruzione del collo del laringocele può esitare in un laringomucocele e, in caso di infezione, in un laringopiocele."},"nl":{"name":"Laryngocele","definition":"Een zeldzame congenitale anomalie van larynx, gekarakteriseerd door een abnormale dilatatie van de laryngeale ventrikels die is gevuld met lucht, in verbinding staat met laryngeaal lumen, en beperkt blijft tot de valse stembanden of zich naar boven toe uitbreidt en door de membrana thyrohyoidea uitpuilt in de nek. Mogelijke symptomen zijn onder meer hoest, heesheid, stridor, pijnlijke keel, en uni- of bilaterale zwelling van nek. Verstopping van de hals van de laryngocele kan leiden tot laryngomucocele, en vormt laryngopyocele bij infectie."},"pt":{"name":"Laringocelo"},"pl":{"name":"Torbiel krtani"},"cs":{"name":"Laryngokéla"},"uk":{"name":"Ларингоцеле","definition":"A rare congenital laryngeal anomaly characterized by an abnormal dilation of the laryngeal saccule that is filled with air, maintains communication with the laryngeal lumen, and is either confined to the false vocal fold or extends upward, protruding through the thyrohyoid membrane to the neck. Symptoms may include cough, hoarseness, stridor, sore throat and uni- or bilateral swelling of the neck. Blockage of the laryngocele neck can result isn laryngomucocele, and forms laryngopyocele when infected."},"zh":{"name":"喉囊肿"},"tr":{"name":"Laringosel"}},"xrefs":[{"source":"ICD-10","code":"Q31.3","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"LA71.1","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"360056769"},{"source":"MONDO","code":"0016530","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D059608","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0265761","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"3191","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10023885","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98036,"name":"Rare otorhinolaryngologic disease"},"parents":[{"orpha":156249,"name":"Larynx anomaly","classifications":[147,200]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.4,"area":"Worldwide","status":"Validated","source":"32487170[PMID]_ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"}],"phenotypes":null}