{"orpha":231,"name":"Dracunculiasis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Dracunculosis","Guinea worm disease","Medina worm disease","Medinensis"],"definition":"Dracunculiasis (Guinea worm disease) is a neglected tropical disease (NTD) characterized by a painful burning skin lesion from which the <i>Dracunculus medinensis</i> parasite emerges approximately 1 year after infection resulting from consumption of unsafe drinking water containing parasite-infected copepods (<i>Cyclops spp.</i>, microcrustacea also called water fleas).","note":null,"url":"https://raremap.alftech.space/d/ORPHA-231/","orphanet_url":"https://www.orpha.net/en/disease/detail/231","names":{"fr":{"name":"Dracunculose","synonyms":["Filariose de Médine","Maladie du ver de Guinée"],"definition":"La dracunculose (maladie du ver de Guinée) est une maladie tropicale négligée caractérisée par une lésion cutanée avec des douleurs type brûlures de laquelle le parasite <i>Dracunculus medinensis</i> est expulsé environ 1 an après l'infection contractée lors de la consommation d'eau potable contaminée (parasites copépodes <i>Cyclops spp.</i>, microcrustacés aussi appelés puces aquatiques)."},"de":{"name":"Drakunkulose","synonyms":["Drakontiase","Guineawurm-Infektion","Medinawurm-Krankheit"],"definition":"Die Drakunkulose (Medinawurm-Krankheit) ist eine vernachlässigte tropische Erkrankung (NTD) mit schmerzhaft brennenden Hautläsionen, aus denen der Parasit <i>Dracunculus medinensis</i> auftaucht, etwa ein Jahr nach Infektion durch kontaminiertes Trinkwasser. Überträger sind hierbei parasiteninfizierte Copepoden (<i>Cyclops</i> spp., Wasserflöhe)."},"es":{"name":"Dracunculiasis","synonyms":["Dracunculosis","Enfermedad de la lombriz de Guinea","Enfermedad de la lombriz de Medina","Medinensis"],"definition":"La dracunculiasis (enfermedad del gusano de Guinea) es una enfermedad tropical desatendida (ETD) caracterizada por lesiones cutáneas dolorosas con sensación de ardor de las que emerge el parásito <i>Dracunculus medinensis</i>, aproximadamente un año después de la infección, como resultado de la ingestión de agua no apta para el consumo que contiene copépodos (<i>Cyclops spp.</i>, microcrustáceos también llamados pulgas de agua) infectados con el parásito."},"it":{"name":"Dracunculiasi","synonyms":["Dracunculosi","Malattia del verme della Guinea","Malattia della filaria di Medina","Medinensis"],"definition":"La dracunculiasi (malattia del verme della Guinea) è una malattia tropicale rara (NTD) caratterizzata da una lesione cutanea associata a dolore bruciante. È causata dal parassita <i>Dracunculus medinensis</i>, che fuoriesce dalla lesione circa 1 anno dopo l'infezione, provocata dall'ingestione di acqua contaminata, contenente copepodi (<i>Cyclops spp.</i>, microcrostacei noti anche come pulci d'acqua) infettati dai parassiti."},"nl":{"name":"Dracunculiasis","synonyms":["Dracunculosis","Dracunculus medinensis","Guineaworm-ziekte","Medinaworm-ziekte","Medinensis"],"definition":"Dranunculiasis (Guineawormziekte) is een verwaarloosde tropische ziekte die gekenmerkt wordt door een pijnlijke brandende huidlaesie van waaruit de <i>Dracunculus medinensis</i>-parasiet tevoorschijn komt ongeveer 1 jaar na infectie, die het resultaat is van de consumptie van onveilig drinkwater dat met parasieten geïnfecteerde copepoden (<i>Cyclops spp.</i>, microcrustaceeën die ook roeipootkreeftjes genoemd worden) bevat."},"pt":{"name":"Dracunculiose"},"pl":{"name":"Drakunkuloza","synonyms":["Dracunculosis","Guinea worm disease","Medina worm disease","Medinensis"]},"cs":{"name":"Drakunkulóza","synonyms":["Dracunculosis","Guinea worm disease","Medina worm disease","Medinensis"]},"uk":{"name":"Дракункульоз","synonyms":["Дракункульоз","Хвороба гвінейських червяків","Медінська глистяна хвороба","Medinensis"],"definition":"Dracunculiasis (Guinea worm disease) is a neglected tropical disease (NTD) characterized by a painful burning skin lesion from which the <i>Dracunculus medinensis</i> parasite emerges approximately 1 year after infection resulting from consumption of unsafe drinking water containing parasite-infected copepods (<i>Cyclops spp.</i>, microcrustacea also called water fleas)."},"zh":{"name":"龙线虫病","synonyms":["麦地那龙线虫病"]},"tr":{"name":"Drakunkuliyaz","synonyms":["Medinensis","Dracunculosis","Gine solucanı hastalığı","Medine solucanı hastalığı"]}},"xrefs":[{"source":"ICD-10","code":"B72","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1F64","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1662537619"},{"source":"MONDO","code":"0016472","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D004320","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0013100","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"6286","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10013618","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":2034,"name":"Filariasis","classifications":[203]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":"<1 / 1 000 000","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2016-06-01","source":null,"terms":[{"hpo":"HP:0008066","label":"Abnormal blistering of the skin","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002014","label":"Diarrhea","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0011134","label":"Low-grade fever","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002017","label":"Nausea and vomiting","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000989","label":"Pruritus","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0000988","label":"Skin rash","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0200042","label":"Skin ulcer","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001482","label":"Subcutaneous nodule","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0001369","label":"Arthritis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100658","label":"Cellulitis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100326","label":"Immunologic hypersensitivity","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001376","label":"Limitation of joint mobility","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0100838","label":"Recurrent cutaneous abscess formation","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001371","label":"Flexion contracture","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100758","label":"Gangrene","frequency":"Occasional (29-5%)","criteria":null}]}}