{"orpha":213716,"name":"Squamous cell carcinoma of the corpus uteri","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Endometrial squamous cell carcinoma"],"definition":"Squamous cell carcinoma of the corpus uteri is a rare cancer of corpus uteri composed of squamous cells of varying degree of differentiation that usually affects postmenopausal women and presents with abnormal vaginal discharge, dysfunctional bleeding, abdominal pain and distension. It is often associated with cervical stenosis and pyometra.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-213716/","orphanet_url":"https://www.orpha.net/en/disease/detail/213716","names":{"fr":{"name":"Carcinome épidermoïde du corps de l'utérus","synonyms":["Carcinome épidermoïde de l'endomètre"],"definition":"Un cancer rare du corps de l'utérus composé de cellules squameuses à différents stades de différenciation. Il affecte habituellement les femmes post-ménopausées, et se présente par une perte vaginale anormale, un saignement dysfonctionnel, une douleur et une distension abdominales. Il est souvent associé à une sténose cervicale et à un pyomètre."},"de":{"name":"Plattenepithelkarzinom des Corpus uteri","synonyms":["Plattenepithelkarzinom, endometriales"],"definition":"Das Plattenepithelkarzinom des Corpus uteri ist eine seltene Krebserkrankung des Gebärmutterkörpers. Es besteht aus Plattenepithelzellen unterschiedlichen Differenzierungsgrades und betrifft zumeist postmenopausale Frauen. Häufige Anzeichen sind abnormaler Vaginalausfluss, dysfunktionalen Blutungen, Unterleibsschmerzen und Blähungen. Oft sind Zervixstenose und Pyometra assoziiert."},"es":{"name":"Carcinoma de células escamosas de cuerpo de útero","synonyms":["Carcinoma endometrial de células escamosas"],"definition":"El carcinoma de células escamosas de cuerpo de útero es un cáncer poco frecuente del cuerpo uterino compuesto por células escamosas de diferente grado de diferenciación que generalmente afecta a mujeres posmenopáusicas y que se presenta con flujo vaginal anómalo, sangrado disfuncional, dolor abdominal y distensión. A menudo se asocia con estenosis cervical y piometra."},"it":{"name":"Carcinoma a cellule squamose del corpo uterino","synonyms":["Carcinoma a cellule squamose dell'endometrio"],"definition":"Il carcinoma a cellule squamose del corpo uterino è un tumore raro del corpo dell'utero, composto da cellule squamose variabilmente differenziate. Di solito colpisce le donne in menopausa ed esordisce con perdite vaginali anomale, emorragie disfunzionali, dolore e distensione addominale. Spesso si associa alla stenosi cervicale e a piometra."},"nl":{"name":"Plaveiselcelcarcinoom van corpus uteri","synonyms":["Endometriaal plaveiselcelcarcinoom","Plaveiselcelcarcinoom van baarmoederlichaam"],"definition":"Plaveiselcelcarcinoom van het baarmoederlichaam is een zeldzame kanker van het baarmoederlichaam bestaande uit plaveiselcellen met een variabele differentiatiegraad die meestal postmenopauzale vrouwen treft en zich voordoet met abnormale vaginale afscheiding, disfunctionele bloeding, en abdominale pijn en distensie. Het is vaak geassocieerd met cervicale stenose en pyometra (baarmoederontsteking)."},"pt":{"name":"Carcinoma de células escamosas do corpo uterino"},"pl":{"name":"Rak płaskonabłonkowy trzonu macicy","synonyms":["Rak płaskonabłonkowy endometrium"]},"cs":{"name":"Dlaždicobuněčný karcinom corpus uteri","synonyms":["Endometriální dlaždicobuněčný karcinom"]},"uk":{"name":"Плоскоклітинний рак тіла матки","synonyms":["Плоскоклітинний рак ендометрія"],"definition":"Squamous cell carcinoma of the corpus uteri is a rare cancer of corpus uteri composed of squamous cells of varying degree of differentiation that usually affects postmenopausal women and presents with abnormal vaginal discharge, dysfunctional bleeding, abdominal pain and distension. It is often associated with cervical stenosis and pyometra."},"zh":{"name":"子宫体鳞状细胞癌","synonyms":["子宫内膜鳞状细胞癌"],"definition":"子宫体鳞状细胞癌是一种罕见的子宫体癌，由分化程度不同的鳞状细胞组成，常累及绝经后妇女，表现为异常阴道分泌物、功能失调性出血、腹痛和腹胀。本病常伴有宫颈狭窄和子宫积脓。"},"tr":{"name":"Korpus uteri'nin skuamöz hücreli karsinomu","synonyms":["Endometrial skuamöz hücreli karsinom"]}},"xrefs":[{"source":"ICD-10","code":"C54.1","qualifier":"BTNT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2C76.Y","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"965173367"},{"source":"MONDO","code":"0016266","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4707099","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":213569,"name":"Rare cancer of corpus uteri","classifications":[202,205]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.12,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.039,"area":"Belgium","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.014,"area":"Croatia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.012,"area":"Finland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.044,"area":"Germany","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.083,"area":"Ireland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.031,"area":"Malta","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.011,"area":"Norway","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.045,"area":"Portugal","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.034,"area":"Slovakia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.019,"area":"Slovenia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.039,"area":"Spain","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.056,"area":"Switzerland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.018,"area":"Netherlands","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"<1 / 1 000 000","value":0.041,"area":"United Kingdom","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.117,"area":"Austria","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.12,"area":"Bulgaria","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.177,"area":"Czech Republic","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.139,"area":"Estonia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.113,"area":"Italy","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.173,"area":"Latvia","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.228,"area":"Lithuania","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"},{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.106,"area":"Poland","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":null}