{"orpha":213605,"name":"Carcinofibroma of the corpus uteri","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Carcinofibroma of the corpus uteri is an extremely rare subtype of mixed müllerian tumor characterized by the presence of a uterine neoplasm which simuntaneously presents a malignant epithelial component (carcinomatous glands) and a benign mesenchymal component. Clinical presentation typically includes dysfunctional vaginal bleeding, abnormal vaginal discharge and/or lower abdominal pain.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-213605/","orphanet_url":"https://www.orpha.net/en/disease/detail/213605","names":{"fr":{"name":"Carcinofibrome du corps de l'utérus","definition":"Sous-type rare de tumeur müllérienne mixte caractérisé par la présence d'un néoplasme utérin présentant simultanément une composante épithéliale maligne (glandes carcinomateuses) et une composante mésenchymateuse bénigne. La présentation clinique comprend généralement des saignements utérins dysfonctionnels et des écoulements vaginaux anormaux et/ou des douleurs abdominales basses."},"de":{"name":"Karzinofibrom des Corpus uteri"},"es":{"name":"Carcinofibroma de cuerpo de útero","definition":"El carcinofibroma de cuerpo de útero es un subtipo muy poco frecuente de tumor mülleriano mixto caracterizado por la presencia de una neoplasia uterina que presenta simultáneamente un componente epitelial maligno (glándulas carcinomatosas) y un componente mesenquimatoso benigno. Por lo general, los hallazgos clínicos incluyen sangrado vaginal disfuncional, flujo vaginal anómalo y/o dolor en la porción inferior del abdomen."},"it":{"name":"Carcinofibroma del corpo dell'utero","definition":"Il carcinofibroma del corpo dell'utero è un sottotipo molto raro di tumore misto mülleriano, che presenta contemporaneamente una componente epiteliale maligna (ghiandole carcinomatose) ed una mesenchimale benigna. Di solito il quadro clinico comprende le emorragie e le perdite vaginali e/o il dolore nella parte inferiore dell'addome."},"nl":{"name":"Carcinofibroom van corpus uteri","synonyms":["Carcinofibroom van baarmoederlichaam"],"definition":"Carcinofibroom van het baarmoederlichaam is een uiterst zeldzaam subtype van gemengde Mülleriaanse tumor, en wordt gekarakteriseerd door de aanwezigheid van een uterien neoplasma dat tegelijk een kwaadaardige epitheliale component (carcinomateuze klieren) en een goedaardige mesenchymale component vertoont. Het typische klinische beeld omvat disfunctionele vaginale bloeding, abnormale vaginale afscheiding en/of pijn in de onderbuik."},"pt":{"name":"Carcinofibroma do corpo uterino"},"pl":{"name":"Włókniakorak trzonu macicy"},"cs":{"name":"Karcinofibrom těla děložního"},"uk":{"name":"Карцинофіброма тіла матки","definition":"Carcinofibroma of the corpus uteri is an extremely rare subtype of mixed müllerian tumor characterized by the presence of a uterine neoplasm which simuntaneously presents a malignant epithelial component (carcinomatous glands) and a benign mesenchymal component. Clinical presentation typically includes dysfunctional vaginal bleeding, abnormal vaginal discharge and/or lower abdominal pain."},"zh":{"name":"子宫体癌纤维瘤","definition":"子宫体癌纤维瘤是一种极罕见的恶性苗勒管混合瘤，其特征为子宫肿瘤同时表出现恶性上皮成分（癌腺体）和良性间充质成分。临床表现通常包括功能失调性阴道出血、异常阴道分泌物和/或下腹痛。"},"tr":{"name":"Korpus uteri karsinofibromu"}},"xrefs":[{"source":"ICD-10","code":"C54.0","qualifier":"BTNT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"C54.1","qualifier":"BTNT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"C54.2","qualifier":"BTNT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"C54.3","qualifier":"BTNT","icd_relation":"attributed","validated":true},{"source":"ICD-10","code":"C54.8","qualifier":"BTNT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2B5D.1","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1125482540"},{"source":"MONDO","code":"0016258","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4755313","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":213589,"name":"Malignant mixed epithelial and mesenchymal tumor of corpus uteri","classifications":[202,205]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":null}