{"orpha":213512,"name":"Malignant mixed Müllerian tumor of the ovary","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["MMMT of the ovary","Ovarian carcinosarcoma","Ovarian malignant mixed Müllerian tumor","Ovarian malignant mixed epithelial mesenchymal tumor"],"definition":"Malignant mixed Müllerian tumor of the ovary is a rare and very aggressive neoplasm presenting most commonly in postmenopausal women and is composed of adenocarcinomatous and sarcomatous elements and, depending on the types of these elements, can be classified as homologous or heterologous. It often has a poor prognosis.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-213512/","orphanet_url":"https://www.orpha.net/en/disease/detail/213512","names":{"fr":{"name":"Tumeur maligne mixte müllérienne de l'ovaire","synonyms":["Carcinosarcome de l'ovaire","MMMT de l'ovaire"],"definition":"Tumeur rare et très agressive qui se manifeste le plus souvent chez les femmes ménopausées. Elle est composée d'éléments adénocarcinomateux et sarcomateux et, selon le type de ces éléments, peut être classée comme homologue ou hétérologue. Elle est souvent de mauvais pronostic."},"de":{"name":"Maligner Müllerscher Mischtumor des Ovars","synonyms":["Gemischte epitheliale und mesenchymale Tumoren des Ovars","Karzinosarkom des Ovars","MMMT des Ovars"]},"es":{"name":"Tumor mülleriano mixto maligno de ovario","synonyms":["Carcinosarcoma ovárico","TMMM del ovario","Tumor ovárico maligno mixto epitelial y mesenquimatoso","Tumor ovárico mülleriano mixto maligno"],"definition":"Es una neoplasia poco frecuente y muy agresiva que se presenta con mayor frecuencia en mujeres posmenopáusicas y que está compuesta por elementos adenocarcinomatosos y sarcomatosos y, dependiendo de los tipos de estos elementos, puede clasificarse como homóloga o heteróloga. Suele tener mal pronóstico."},"it":{"name":"Tumore misto maligno mesenchimale ed epiteliale dell'ovaio","synonyms":["Carcinosarcoma dell'ovaio"]},"nl":{"name":"Maligne mengtumor van Müller van ovarium","synonyms":["MMMT van het ovarium","Maligne mengtumor van Müller van eierstok","Ovarieel carcinosarcoom","Ovariële maligne gemengde epitheliale mesenchymale tumor","Ovariële maligne mengtumor van Müller"],"definition":"Maligne gemengde epitheliale en mesenchymale ovariumtumor is een zeldzaam en zeer agressief neoplasma dat meestal voorkomt bij vrouwen in de postmenopauze en dat bestaat uit adenocarcinomateuze en sarcomateuze elementen, en afhankelijk van de types van deze elementen kan het geclassificeerd worden als homoloog of heteroloog. De prognose is vaak ongunstig."},"pt":{"name":"Tumor maligno mesenquimatoso e epitelial misto do ovário"},"pl":{"name":"Złośliwy mieszany guz jajnika z przewodów Mullera","synonyms":["Mięsakorak jajnika","Złośliwy mieszany guz jajnika z nabłonka mezenchymalego"]},"cs":{"name":"Maligní mesenchymální nádor ovaria","synonyms":["Ovariální karcinosarkom"]},"uk":{"name":"Злоякісна змішана мюллерова пухлина яєчника","synonyms":["МММТ яєчника","Карциносаркома яєчників","Злоякісна змішана епітеліальна мезенхімальна пухлина яєчника","Злоякісна змішана мюллерова пухлина яєчників"],"definition":"Malignant mixed Müllerian tumor of the ovary is a rare and very aggressive neoplasm presenting most commonly in postmenopausal women and is composed of adenocarcinomatous and sarcomatous elements and, depending on the types of these elements, can be classified as homologous or heterologous. It often has a poor prognosis."},"zh":{"name":"卵巢恶性混合性苗勒管瘤","synonyms":["卵巢恶性混合性上皮间质瘤"],"definition":"卵巢恶性苗勒管混合瘤是一种罕见且侵袭性极强的肿瘤，最常见于绝经后妇女，由腺癌和肉瘤组成，可根据成分的类型分为以下2类：同源和异源。该病预后往往很差。"},"tr":{"name":"Yumurtalıkta habis karma M³llerian tümörü","synonyms":["Overin MMMT'si","Overin karsinosarkomu","Overin habis karma Müllerian tümörü","Overin habis karma epitel mezenkimal tümörü"]}},"xrefs":[{"source":"ICD-10","code":"C56","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"2B5D.0","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"2072916704"},{"source":"MONDO","code":"0003792","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0392998","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"7296","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":250908,"name":"Rare neoplastic disease"},"parents":[{"orpha":398934,"name":"Malignant epithelial tumor of ovary","classifications":[202,205]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 1 000 000","value":0.12,"area":"Europe","status":"Validated","source":"RARECARE surveillance of rare cancers in Europe[OTHER]"}],"phenotypes":null}