{"orpha":209964,"name":"Solitary rectal ulcer syndrome","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Solitary rectal ulcer syndrome (SRUS) is a rare rectal disease characterized by rectal bleeding, abdominal pain, passage of mucus, sensation of incomplete evacuation, straining at defecation and rectal prolapse, secondary to ischemic changes in the rectum.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-209964/","orphanet_url":"https://www.orpha.net/en/disease/detail/209964","names":{"fr":{"name":"Syndrome de l'ulcère solitaire du rectum","definition":"Le syndrome de l'ulcère solitaire du rectum (SUSR) est une maladie rectale rare caractérisée par une hémorragie rectale, une douleur abdominale, des émissions de glaires, une sensation d'évacuation incomplète, une dyschésie et un prolapsus rectal, secondaire à des changements ischémiques dans le rectum."},"de":{"name":"Solitary-rectal-ulcer-Syndrom","synonyms":["Rektumulkus, solitärer","Solitäres Geschwür des Rektums"],"definition":"Das solitäre Geschwür des Rektums ist eine seltene Erkrankung mit rektalen Blutungen, Leibschmerzen, Absonderung von Schleim, dem Gefühl unvollständiger Entleerung des Darms, Schmerzen beim Stuhlgang, Rektumprolaps. Die Krankheit tritt im Gefolge ischämischer Veränderungen des Rektums auf."},"es":{"name":"Síndrome de úlcera rectal solitaria","definition":"El síndrome de úlcera rectal solitaria (SRUS) es una enfermedad rectal poco frecuente que se caracteriza por sangrado rectal, dolor abdominal, pasaje de moco, sensación de evacuación incompleta, esfuerzo al defecar y prolapso rectal, secundario a cambios isquémicos en el recto."},"it":{"name":"Sindrome dell'ulcera solitaria del retto","definition":"La sindrome dell'ulcera solitaria del retto (SRUS) è una malattia rara del retto, caratterizzata da sanguinamento rettale, dolore addominale, emissione di muco, sensazione di evacuazione incompleta, sforzo durante la defecazione e prolasso rettale secondario alle alterazioni ischemiche del retto."},"nl":{"name":"Solitaire rectale ulcus-syndroom","definition":"Een zeldzame aandoening van rectum, gekenmerkt door rectaal bloedverlies, abdominale pijn, passage van mucus, gevoel van onvolledige darmlediging, inspanning bij defecatie, en rectumprolaps, secundair aan ischemische veranderingen in rectum."},"pt":{"name":"Síndrome úlcera retal solitária"},"pl":{"name":"Zespół samotnego wrzodu odbytnicy"},"cs":{"name":"Syndrom solitárního rektálního vředu"},"uk":{"name":"Синдром солітарної виразки прямої кишки","definition":"Solitary rectal ulcer syndrome (SRUS) is a rare rectal disease characterized by rectal bleeding, abdominal pain, passage of mucus, sensation of incomplete evacuation, straining at defecation and rectal prolapsed, secondary to ischemic changes in the rectum."},"zh":{"name":"孤立性直肠溃疡综合征","definition":"孤立性直肠溃疡综合征（SRUS）是一种罕见的直肠疾病，其主要临床表现为直肠出血、腹痛、粘液便、排便不尽、排便困难和直肠脱垂，继发于直肠缺血性疾病。"},"tr":{"name":"Soliter rektal ülser sendromu"}},"xrefs":[{"source":"ICD-10","code":"K62.6","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"DB33.0","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1677843970"},{"source":"MONDO","code":"0016208","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C4274343","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":97935,"name":"Rare gastroenterologic disease"},"parents":[{"orpha":117569,"name":"Rare intestinal disease","classifications":[152]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["Adult"],"prevalence":[{"type":"Annual incidence","qualification":"Value and class","class":"1-9 / 100 000","value":1.0,"area":"Europe","status":"Not yet validated","source":"18188027[PMID]"},{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2021-12-08","source":"31687110[PMID]_32097373[PMID]_29718850[PMID]","terms":[{"hpo":"HP:0002573","label":"Hematochezia","frequency":"Very frequent (99-80%)","criteria":null},{"hpo":"HP:0002027","label":"Abdominal pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0500005","label":"Anal pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012450","label":"Chronic constipation","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002254","label":"Intermittent diarrhea","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0000002","label":"Abnormality of body height","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012390","label":"Anal fissure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001903","label":"Anemia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025085","label":"Bloody diarrhea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0025086","label":"Bloody mucoid diarrhea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0000722","label":"Compulsive behaviors","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0004325","label":"Decreased body weight","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002574","label":"Episodic abdominal pain","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002035","label":"Rectal prolapse","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012702","label":"Tenesmus","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012425","label":"Stercoral ulcer","frequency":"Very rare (<4-1%)","criteria":null}]}}