{"orpha":208999,"name":"Paraneoplastic sensory ganglionopathy","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":["Paraneoplastic sensory neuronopathy"],"definition":null,"note":null,"url":"https://raremap.alftech.space/d/ORPHA-208999/","orphanet_url":"https://www.orpha.net/en/disease/detail/208999","names":{"fr":{"name":"Ganglionopathie sensitive paranéoplasique","synonyms":["Neuronopathie sensitive paranéoplasique"]},"de":{"name":"Ganglionopathie, paraneoplastische sensorische","synonyms":["Neuropathie, paraneoplastische sensorische"]},"es":{"name":"Ganglionopatía sensitiva paraneoplásica","synonyms":["Neuropatía sensitiva paraneoplásica"]},"it":{"name":"Ganglionopatia sensitiva paraneoplastica","synonyms":["Neuropatia sensitiva paraneoplastica"]},"nl":{"name":"Paraneoplastische sensorische ganglionopathie","synonyms":["Paraneoplastische sensorische neuronopathie"]},"pt":{"name":"Ganglionopatia sensitiva paraneoplásica"},"pl":{"name":"Paraneoplastyczna gangliopatia czuciowa","synonyms":["Paraneoplastyczna neuropatia czuciowa"]},"cs":{"name":"Paraneoplastická senzorická ganglionopatie","synonyms":["Paraneoplastická senzitivní neuronopatie"]},"uk":{"name":"Паранеопластична сенсорна гангліонопатія","synonyms":["Паранеопластична сенсорна нейронопатія"]},"zh":{"name":"副肿瘤性感觉神经节病","synonyms":["副肿瘤性感觉神经元病"]},"tr":{"name":"Paraneoplastik duyusal ganglionopati","synonyms":["Paraneoplastik duyusal nöronopati"]}},"xrefs":[{"source":"ICD-10","code":"G60.8","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"8E4A.1","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"46072886"},{"source":"MONDO","code":"0016174","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C5679792","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":98006,"name":"Rare neurologic disease"},"parents":[{"orpha":208984,"name":"Acquired sensory ganglionopathy","classifications":[181]},{"orpha":36388,"name":"Paraneoplastic neurologic syndrome","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2025-06-27","source":"24385818[PMID]_35272731[PMID]","terms":[{"hpo":"HP:5000016","label":"Anti-Hu antibody positivity","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002075","label":"Dysdiadochokinesis","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0012534","label":"Dysesthesia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001310","label":"Dysmetria","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0032147","label":"Erythromelalgia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002066","label":"Gait ataxia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0046505","label":"Hand pain","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0033660","label":"Hand paresthesia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0033748","label":"Hypoesthesia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0006886","label":"Impaired distal vibration sensation","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0010829","label":"Impaired temperature sensition","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002311","label":"Incoordination","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002403","label":"Positive Romberg sign","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001315","label":"Reduced tendon reflexes","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0010871","label":"Sensory ataxia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0033125","label":"Follicular lymphoma","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012189","label":"Hodgkin lymphoma","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030360","label":"Large cell lung carcinoma","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0100634","label":"Neuroendocrine neoplasm","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030357","label":"Small cell lung carcinoma","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0430058","label":"Anti-herpes simplex antibody positivity","frequency":"Excluded (0%)","criteria":null},{"hpo":"HP:0100502","label":"Decreased circulating vitamin B12 concentration","frequency":"Excluded (0%)","criteria":null}]}}