{"orpha":207000,"name":"Fungal myositis","type":"Disease","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"A rare acquired skeletal muscle disease characterized by inflammation of a muscle due to infection with a fungus, usually occurring in an immunocompromised host. General symptoms are pain, tenderness, swelling, and/or weakness in the affected muscle. Most common causative agent are <i>Candida</i> species, with myositis developing in the setting of systemic candidiasis, typically as diffuse, multiple microabscesses. Other fungal pathogens potentially causing myositis are <i>Cryptococcus neoformans</i>, <i>Histoplasma capsulatum</i>, <i>Coccidioides</i> species, or <i>Aspergillus</i> species, among others.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-207000/","orphanet_url":"https://www.orpha.net/en/disease/detail/207000","names":{"fr":{"name":"Myosite fongique","definition":"Maladie acquise du muscle squelettique rare caractérisée par l'inflammation d'un muscle due à une infection par un champignon, survenant généralement chez un hôte immunodéprimé. Les signes cliniques généraux sont la douleur, la sensibilité, le gonflement et/ou la faiblesse du muscle affecté. L'agent causal le plus courant est l'espèce <i>Candida</i>, la myosite se développant dans le cadre d'une candidose systémique, typiquement sous forme de microabcès multiples et diffus. Les autres agents pathogènes fongiques susceptibles de provoquer une myosite sont, notamment, <i>Cryptococcus neoformans</i>, <i>Histoplasma capsulatum</i>, les espèces de Coccidioides ou les espèces d'Aspergillus."},"de":{"name":"Myositis bei Pilzerkrankungen","definition":"Eine seltene erworbene Skelettmuskelerkrankung, die durch eine Entzündung eines Muskels aufgrund einer Pilzinfektion gekennzeichnet ist und in der Regel bei einem immungeschwächten Wirt auftritt. Allgemeine Symptome sind Schmerzen, Empfindlichkeit, Schwellung und/oder Schwäche im betroffenen Muskel. Die häufigsten Erreger sind <i>Candida</i>-Spezies, wobei sich die Myositis im Rahmen einer systemischen Candidose entwickelt, typischerweise als diffuse, multiple Mikroabszesse. Andere Pilzerreger, die eine Myositis verursachen können, sind unter anderem <i>Cryptococcus neoformans</i>, <i>Histoplasma capsulatum</i>, <i>Coccidioides</i>-Spezies oder <i>Aspergillus</i>-Spezies."},"es":{"name":"Miositis fúngica","definition":"Es una enfermedad adquirida y poco frecuente del músculo esquelético caracterizada por una inflamación muscular debida a una infección fúngica, que suele ocurrir en huéspedes inmunodeprimidos. Los síntomas generales son dolor, sensibilidad, inflamación y/o debilidad del músculo afectado. El agente causal más frecuente son las especies de <i>Candida</i>, desarrollándose la miositis en el contexto de una candidiasis sistémica, por lo general, como microabscesos múltiples y difusos. Otros hongos patógenos que pueden causar la miositis son <i>Cryptococcus neoformans</i>, <i>Histoplasma capsulatum</i>, especies de <i>Coccidioides</i> o especies de <i>Aspergillus</i>, entre otras."},"it":{"name":"Miosite fungina","definition":"Si tratta di una malattia rara muscolo-scheletrica acquisita, caratterizzata dall'infiammazione di un muscolo secondaria a un'infezione da fungo, che in genere colpisce un ospite immunocompromesso. I sintomi comprendono il dolore, la sensibilità, il gonfiore e/o la debolezza del muscolo interessato. L'agente più comunemente responsabile della malattia è la specie <i>Candida</i> e la miosite si sviluppa nel quadro di una candidiasi sistemica, in genere sotto forma di microascessi multipli diffusi. Altri patogeni fungini che possono causare la miosite sono il <i>Cryptococcus neoformans</i>, l'<i>Histoplasma capsulatum</i>, la specie <i>Coccidioides</i> e la specie <i>Aspergillus</i>."},"nl":{"name":"Fungale myositis","definition":"Een zeldzame, verworven aandoening van skeletspier, gekarakteriseerd door inflammatie van spier als gevolg van infectie met een fungus, meestal van een immuungecompromitteerde gastheer. Algemene symptomen zijn pijn, gevoeligheid, zwelling, en/of zwakte van aangetaste spier. De meest gangbare ziekteverwekkers behoren tot de soort <i>Candida</i>, waarbij myositis ontwikkelt in de context van systemische candidiasis, doorgaans als diffuse, multipele microabcessen. Andere pathogene schimmels die myositis kunnen veroorzaken, zijn onder meer de soorten <i>Cryptococcus neoformans</i> en <i>Histoplasma capsulatum</i>, of schimmels die behoren tot de geslachten <i>Coccidioides</i> en <i>Aspergillus</i>."},"pt":{"name":"Miosite fúngica"},"pl":{"name":"Grzybicze zapalenie mięśni"},"cs":{"name":"Mykotická myozitida"},"uk":{"name":"Грибковий міозит","definition":"A rare acquired skeletal muscle disease characterized by inflammation of a muscle due to infection with a fungus, usually occurring in an immunocompromised host. General symptoms are pain, tenderness, swelling, and/or weakness in the affected muscle. Most common causative agent are <i>Candida</i> species, with myositis developing in the setting of systemic candidiasis, typically as diffuse, multiple microabscesses. Other fungal pathogens potentially causing myositis are <i>Cryptococcus neoformans</i>, <i>Histoplasma capsulatum</i>, <i>Coccidioides</i> species, or <i>Aspergillus</i> species, among others."},"zh":{"name":"真菌性肌炎","definition":"真菌性肌病是一种罕见的获得性骨骼肌疾病，由真菌感染而导致的肌肉炎症，常发生于免疫功能低下的患者。其主要临床表现为受累肌肉疼痛、压痛、肿胀和/或无力。最常见致病菌为念珠菌，其它真菌病原体包括新型隐球菌、组织胞浆菌、球孢子菌、曲霉等，典型表现为弥漫性、多发性微脓肿。"},"tr":{"name":"Mantar miyoziti"}},"xrefs":[{"source":"ICD-10","code":"M60.0","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"FB30","qualifier":"NTBT","icd_relation":"index","validated":true,"icd11_uri":"1054267564"},{"source":"MONDO","code":"0016130","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0410251","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10086251","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":206988,"name":"Infectious, fungal or parasitic myopathy","classifications":[181]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":["All ages"],"prevalence":[],"phenotypes":null}