{"orpha":2041,"name":"Coronary arterial fistula","type":"Morphological anomaly","group":"Disorder","status":"active","flags":[],"synonyms":[],"definition":"Coronary arterial fistulas are a connection between one or more of the coronary arteries and a cardiac chamber or great vessel.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-2041/","orphanet_url":"https://www.orpha.net/en/disease/detail/2041","names":{"fr":{"name":"Fistule coronaire","definition":"Les fistules artérielles coronariennes correspondent à une communication entre une ou plusieurs artères coronaires et la cavité cardiaque ou les gros vaisseaux."},"de":{"name":"Koronarfistel","definition":"Koronararterien-Fisteln sind Verbindungen zwischen einer oder mehreren Koronararterien und einer Herzkammer oder einem großen Gefäß."},"es":{"name":"Fístula coronario-arterial","definition":"La fístula de la arteria coronaria es una conexión entre una o más de las arterias coronarias y una cámara cardíaca o un gran vaso."},"it":{"name":"Fistole delle arterie coronarie","synonyms":["Fistola coronarocardiaca","Malformazioni delle arterie coronarie"]},"nl":{"name":"Coronaire arteriële fistel","definition":"Coronaire arteriële fistels zijn een verbinding tussen één of meerdere kransslagaders en een hartkamer of groot bloedvat."},"pt":{"name":"Fístula coronario-arterial"},"pl":{"name":"Przetoki tętnic wieńcowych","synonyms":["Malformacje tętnic wieńcowych","Przetoka wieńcowo-sercowa"]},"cs":{"name":"Vrozená píštěl věnčitých tepen","synonyms":["Koronární arteriální malformace","Koronární píštěle"]},"uk":{"name":"Фістула коронарної артерії","definition":"Coronary arterial fistulas are a connection between one or more of the coronary arteries and a cardiac chamber or great vessel."},"zh":{"name":"冠状动脉瘘"},"tr":{"name":"Koroner arter fistülü"}},"xrefs":[{"source":"ICD-10","code":"Q24.5","qualifier":"NTBT","icd_relation":"attributed","validated":true},{"source":"ICD-11","code":"LA8C.2","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1580310858"},{"source":"MONDO","code":"0016081","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0265898","qualifier":"E","icd_relation":null,"validated":true},{"source":"GARD","code":"1533","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10069441","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":1081,"name":"Coronary artery congenital malformation","classifications":[147,148]}],"children":[],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Worldwide","status":"Not yet validated","source":"ORPHANET_24940026[PMID]"}],"phenotypes":{"validation_status":"y","online":"y","validation_date":"2021-08-18","source":"28740588[PMID]_30560560[PMID]_26381209[PMID]_30230248[PMID]","terms":[{"hpo":"HP:0003115","label":"Abnormal EKG","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0005162","label":"Abnormal left ventricular function","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001640","label":"Cardiomegaly","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001635","label":"Congestive heart failure","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031670","label":"Continuous heart murmur","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0002875","label":"Exertional dyspnea","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0031664","label":"Systolic heart murmur","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001649","label":"Tachycardia","frequency":"Frequent (79-30%)","criteria":null},{"hpo":"HP:0001627","label":"Abnormal heart morphology","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001681","label":"Angina pectoris","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001650","label":"Aortic valve stenosis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0011675","label":"Arrhythmia","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001631","label":"Atrial septal defect","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0006689","label":"Bacterial endocarditis","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001647","label":"Bicuspid aortic valve","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030882","label":"Coronary artery aneurysm","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002617","label":"Dilatation","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0030848","label":"Elevated jugular venous pressure","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0012764","label":"Orthopnea","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001962","label":"Palpitations","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001643","label":"Patent ductus arteriosus","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001655","label":"Patent foramen ovale","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0010741","label":"Pedal edema","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002092","label":"Pulmonary arterial hypertension","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0005133","label":"Right ventricular dilatation","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0001279","label":"Syncope","frequency":"Occasional (29-5%)","criteria":null},{"hpo":"HP:0002789","label":"Tachypnea","frequency":"Occasional (29-5%)","criteria":null}]}}