{"orpha":2034,"name":"Filariasis","type":"Category","group":"Group of disorders","status":"active","flags":[],"synonyms":[],"definition":"A parasitic disease caused by tissue-invasive, vector-borne nematodes which can be found anywhere in the human body and that are transmitted to humans through the bite of an infected mosquito or fly or by consumption of unsafe drinking water and which, depending on the subtype can manifest with lymphedema, dermatitis, subcutaneous edema and eye involvement. The disorder is a major public health problem in many tropical and subtropical countries. Six subtypes have been described in the literature: lymphatic filariasis, onchocerciasis, loiasis, mansonelliasis, dirofilariasis and dracunculiasis caused by <i>Wuchereria bancrofti</i> and filarioidea of the genus <i>Brugia</i>; <i>Onchocerca volvulus</i>; <i>Loa loa</i>; <i>Mansonella</i>; <i>Dirofilaria</i>; and <i>Dracunculus medinensis</i>, respectively. Tropical eosinophilia is considered a frequent manifestation.","note":null,"url":"https://raremap.alftech.space/d/ORPHA-2034/","orphanet_url":"https://www.orpha.net/en/disease/detail/2034","names":{"fr":{"name":"Filariose","definition":"La filariose est une maladie parasitaire causée par des nématodes tissulaires invasifs portés par des vecteurs, se localisant n'importe où dans le corps humain. La filariose est transmise à l'homme par piqûre ou morsure (moustiques ou mouches infectés) ou par consommation d'eau non potable. La filariose est un problème majeur de santé publique dans beaucoup de pays tropicaux et subtropicaux. Six sous-types de filariose sont décrits dans la littérature : la filariose lymphatique (FL), l'onchocercose, la loase, la mansonellose, la dirofilariose et la dracunculose , causés par <i>Wuchereria bancrofti</i> et <i>filarioidea</i> du genre <i>Brugia</i> ; <i>Onchocerca volvulus</i> ; <i>Loa loa</i> ; <i>filarioidea</i> du genre <i>Mansonella</i> : <i>Dirofilaria</i> et <i>Dracunculus medinensis</i> respectivement. L'éosinophilie tropicale est considérée comme une manifestation fréquente."},"de":{"name":"Filariose"},"es":{"name":"Filariasis","definition":"Es una parasitosis causada por nematodos invasores de tejidos, de transmisión vectorial, que se pueden localizar en cualquier punto del cuerpo humano y se transmiten por picadura de un mosquito infectado o una mosca o por consumo de agua no potable y que, en función del subtipo, se puede manifestar como edema linfático, dermatitis, edema subcutáneo y afectación ocular. La filariasis es un gran problema de salud pública en muchos países tropicales y subtropicales. Se han descrito seis tipos de filariasis: filariasis linfática, oncocercosis, loasis, mansonelosis, dirofilariasis y dracunculosis (véanse estos términos) causados por <i>Wuchereria bancrofti</i> y por los géneros <i>Brugia</i>; <i>Onchocerca volvulus</i>; <i>Loa loa</i>; <i>Mansonella</i>; <i>Dirofilaria</i>; y <i>Dracunculus medinensis</i> de la familia filarioidea, respectivamente. La eosinofilia tropical es una manifestación frecuente."},"it":{"name":"Filariosi","definition":"La filariosi è una malattia parassitaria causata da nematodi che invadono i tessuti del corpo; sono trasmessi da vettori attraverso il morso di una zanzara o una mosca infetta o attraverso il consumo di acqua non potabile. A seconda del sottotipo, può manifestarsi con linfedema, dermatite, edema sottocutaneo e interessamento oculare. La filariosi rappresenta un grave problema di salute pubblica in molti paesi tropicali e subtropicali. Sono stati descritti sei sottotipi di filariosi: filariosi linfatica, oncocercosi, loiasi, mansonelliasi, dirofilariosi e dracunculiasi (si vedano questi termini), causate rispettivamente da <i>Wuchereria bancrofti</i> e <i>Filarioidea</i> del genere <i>Brugia</i>; <i>Onchocerca volvulus</i>; <i>Loa loa</i>; <i>Mansonella</i>; <i>Dirofilaria</i>; e <i>Dracunculus medinensis</i>. L'eosinofilia tropicale è considerata un segno frequente."},"nl":{"name":"Filariasis","definition":"Een parasitaire ziekte die veroorzaakt wordt door weefsel-invasieve, vector-gedragen nematoden die eender waar in het menselijk lichaam kunnen aangetroffen worden en op mensen worden overgedragen via de beet van een geïnfecteerde mug of vlieg of door de consumptie van onveilig drinkwater, en die zich, afhankelijk van het subtype, kan manifesteren met lymfoedeem, dermatitis, subcutaan oedeem betrokkenheid van het oog. De ziekte is een groot probleem voor de volksgezondheid in vele tropische en subtropische landen. Er werden zes subtypes beschreven in de literatuur: lymfatische filariasis (LF), onchocerciase, loiasis, mansonelliasis, dirofilariase en dracunculiasis, respectievelijk veroorzaakt door <i>Wuchereria bancrofti</i> en filarioidea van het genus <i>Brugia</i>; <i>Onchocerca volvulus</i>; <i>Loa loa</i>; <i>Mansonella</i>; <i>Dirofilaria</i>; en <i>Dracunculus medinensis</i>. Tropische eosinofilie wordt beschouwd als een frequente manifestatie."},"pt":{"name":"Filariose"},"pl":{"name":"Filarioza"},"cs":{"name":"Filarióza"},"uk":{"name":"Філяріоз","definition":"A parasitic disease caused by tissue-invasive, vector-borne nematodes which can be found anywhere in the human body and that are transmitted to humans through the bite of an infected mosquito or fly or by consumption of unsafe drinking water and which, depending on the subtype can manifest with lymphedema, dermatitis, subcutaneous edema and eye involvement. The disorder is a major public health problem in many tropical and subtropical countries. Six subtypes have been described in the literature: lymphatic filariasis, onchocerciasis, loiasis, mansonelliasis, dirofilariasis and dracunculiasis caused by <i>Wuchereria bancrofti</i> and filarioidea of the genus <i>Brugia</i>; <i>Onchocerca volvulus</i>; <i>Loa loa</i>; <i>Mansonella</i>; <i>Dirofilaria</i>; and <i>Dracunculus medinensis</i>, respectively. Tropical eosinophilia is considered a frequent manifestation."},"zh":{"name":"丝虫病"},"tr":{"name":"Filaryaz"}},"xrefs":[{"source":"ICD-10","code":"B74","qualifier":"E","icd_relation":"specific","validated":true},{"source":"ICD-11","code":"1F66","qualifier":"E","icd_relation":"specific","validated":true,"icd11_uri":"1975325075"},{"source":"MONDO","code":"0016075","qualifier":"E","icd_relation":null,"validated":true},{"source":"MONDO","code":"16075","qualifier":"E","icd_relation":null,"validated":true},{"source":"MeSH","code":"D005368","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0016085","qualifier":"E","icd_relation":null,"validated":true},{"source":"MedDRA","code":"10016674","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":68416,"name":"Rare infectious disease"},"parents":[{"orpha":163588,"name":"Rare parasitic disease","classifications":[203]}],"children":[{"orpha":166291,"name":"Dirofilariasis","type":"Disease"},{"orpha":231,"name":"Dracunculiasis","type":"Disease"},{"orpha":2404,"name":"Loiasis","type":"Disease"},{"orpha":2035,"name":"Lymphatic filariasis","type":"Disease"},{"orpha":2459,"name":"Mansonelliasis","type":"Disease"},{"orpha":2737,"name":"Onchocerciasis","type":"Disease"}],"genes":[],"genes_via_subtypes":[],"inheritance":["Not applicable"],"onset":["All ages"],"prevalence":[{"type":"Point prevalence","qualification":"Class only","class":"Unknown","value":0.0,"area":"Europe","status":"Not yet validated","source":"ORPHANET"},{"type":"Point prevalence","qualification":"Class only","class":">1 / 1000","value":0.0,"area":"Specific population","status":"Validated","source":"World Health Organization 2016[OTHER]"}],"phenotypes":null}