{"orpha":1991,"name":"Cleft lip with or without cleft palate","type":"Clinical group","group":"Group of disorders","status":"active","flags":[],"synonyms":["Tessier cleft number 1,2"],"definition":null,"note":"This term does not characterize a disease but a group of diseases. To learn about the diseases included under this term, you can consult the classifications.","url":"https://raremap.alftech.space/d/ORPHA-1991/","orphanet_url":"https://www.orpha.net/en/disease/detail/1991","names":{"fr":{"name":"Fente labiale avec ou sans fente palatine","synonyms":["Fente 1,2 de Tessier"]},"de":{"name":"Lippenspalte mit oder ohne Gaumenspalte"},"es":{"name":"Hendidura labial con o sin paladar hendido","synonyms":["Fisura labial con o sin fisura palatina"]},"it":{"name":"Schisi labiale con o senza schisi palatina"},"nl":{"name":"Gespleten lip met of zonder gespleten verhemelte","synonyms":["Tessier spleet nummer 1,2"]},"pt":{"name":"Fenda labial com ou sem fenda palatina"},"pl":{"name":"Rozszczep wargi z lub bez rozszczepu podniebienia","synonyms":["Rozszczep Tessiera numer 1,2"]},"cs":{"name":"Rozštěp rtu s nebo bez rozštěpu patra","synonyms":["Tessier cleft number 1,2","Rozštěp číslo 1,2 dle Tessiera"]},"uk":{"name":"Розщілина губи з або без розщілини піднебіння","synonyms":["Розщілина Тессьє № 1,2"]},"zh":{"name":"唇裂伴或不伴腭裂","synonyms":["Tessier裂1，2型"]},"tr":{"name":"Yarık damakla birlikte olan veya olmayan yarık dudak","synonyms":["Tessier yarık sayısı 1,2"]}},"xrefs":[{"source":"MONDO","code":"16034","qualifier":"E","icd_relation":null,"validated":true},{"source":"UMLS","code":"C0810364","qualifier":"E","icd_relation":null,"validated":true}],"associations":[],"incoming_associations":[],"preferential_parent":{"orpha":93890,"name":"Rare developmental defect during embryogenesis"},"parents":[{"orpha":155832,"name":"Rare head and neck malformation","classifications":[147]},{"orpha":68329,"name":"Rare maxillo-facial surgical disease","classifications":[209]}],"children":[{"orpha":141291,"name":"Cleft lip and alveolus","type":"Morphological anomaly"},{"orpha":199306,"name":"Cleft lip/palate","type":"Morphological anomaly"},{"orpha":199302,"name":"Isolated cleft lip","type":"Morphological anomaly"}],"genes":[],"genes_via_subtypes":[],"inheritance":[],"onset":[],"prevalence":[{"type":"Prevalence at birth","qualification":"Class only","class":"6-9 / 10 000","value":0.0,"area":"Worldwide","status":"Validated","source":"20507242[PMID]"},{"type":"Prevalence at birth","qualification":"Value and class","class":">1 / 1000","value":190.5,"area":"Japan","status":"Validated","source":"22374000[PMID]"},{"type":"Prevalence at birth","qualification":"Value and class","class":"6-9 / 10 000","value":77.5,"area":"United States","status":"Validated","source":"22374000[PMID]"}],"phenotypes":null}